RESUMO
We report a case of secondary skin tuberculosis due to endogenous secondary infection in a 27-year-old subject affected by ulcerative colitis. The clinical appearance the lesion was atypical and its classification uncertain. The morphology of the lesion and the fact that the primary tubercular complex, at pulmonary level, was masked by a simultaneous candidiasis infection were probably due to cell-mediated immunodeficiency consequent to the ulcerative colitis and on-going therapy (Salazopyrin and prednisone). Rapid remission of cutaneous and pulmonary lesions was achieved following specific therapy (rifampicin, isoniazid, ethambutol).
Assuntos
Colite Ulcerativa/complicações , Tuberculose Cutânea/diagnóstico , Adulto , Colite Ulcerativa/tratamento farmacológico , Colite Ulcerativa/imunologia , Etambutol/uso terapêutico , Humanos , Isoniazida/uso terapêutico , Prednisona/uso terapêutico , Rifampina/uso terapêutico , Sulfassalazina/uso terapêutico , Tuberculose Cutânea/tratamento farmacológico , Tuberculose Cutânea/etiologia , Tuberculose Pulmonar/diagnóstico , Tuberculose Pulmonar/tratamento farmacológicoRESUMO
The Authors describe two cases of Sporotrichoid infection characterized by the onset, above previous skin accidental injuries, of a papulo-pustular lesion, with further development of centripetal satellite lesions similar to the first one. A precise etiological definition was possible only after the cultural,l mycological and bacteriological examination of biopsy material. The very similar clinical features of the two cases were due to different etiological pathogens: Sporothrix schenckii in one case and Mycobacterium marinum in the other case. A complete healing of the skin lesion was obtained with Itraconazole in the first case and Rifampin in the second case.
Assuntos
Infecções por Mycobacterium não Tuberculosas/diagnóstico , Dermatopatias Infecciosas/diagnóstico , Esporotricose/diagnóstico , Idoso , Biópsia , Diagnóstico Diferencial , Feminino , Humanos , Itraconazol , Cetoconazol/análogos & derivados , Cetoconazol/uso terapêutico , Masculino , Pessoa de Meia-Idade , Infecções por Mycobacterium não Tuberculosas/tratamento farmacológico , Micobactérias não Tuberculosas/isolamento & purificação , Rifampina/uso terapêutico , Dermatopatias Infecciosas/microbiologia , Sporothrix/isolamento & purificação , Esporotricose/tratamento farmacológicoRESUMO
The Authors describe two cases of notalgia paresthesica, a disorder with localized pruritus of the back and hypesthesia for touch possibly due to a sensory neuropathy involving the posterior primary rami of thoracic nerve T2 through T6. The condition is not rare, but underdiagnosed for the poor clinical relevance. The possible X-linked hereditary transmission and other pathogenetic hypotheses are discussed.
Assuntos
Dorso , Neuropatias Hereditárias Sensoriais e Autônomas/genética , Hipestesia/genética , Prurido/genética , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Transtornos da Pigmentação/genética , Pigmentação da Pele , Nervos Espinhais/fisiopatologiaRESUMO
Ile-de-France ewes had high plasma progesterone concentrations during early summer-late winter. Gentile-di-Puglia ewes had high progesterone values during the winter-spring-summer period but during autumn progesterone values were very low and oestrous behaviour was not displayed. The comparison with Ile-de-France ewes indicates that a phase shift occurs in the annual ovarian activity in ewes of the Gentile-di-Puglia breed.
Assuntos
Progesterona/sangue , Estações do Ano , Ovinos/sangue , Animais , Feminino , Luz , Ovário/fisiologiaRESUMO
The profiles of estradiol (E2), progesterone (P), and androstenedione (A), have been studied for the first time in cyclic Gentile di Puglia ewes. Estradiol peaks at estrus whereas progesterone levels are high during the luteal phase. Androstenedione does not show meaningful cyclic fluctuation. All hormones examined show also a pulsatile pattern when plasma was collected hourly.
Assuntos
Estro , Hormônios Esteroides Gonadais/sangue , Ovinos/sangue , Androstenodiona/sangue , Animais , Estradiol/sangue , Feminino , Progesterona/sangue , Ovinos/fisiologiaRESUMO
Seasonal plasma testosterone and androstenedione levels were determined by radioimmunoassay in the Gentile di Puglia ram. Androstenedione remains steady throughout the years, while testosterone shows seasonal changes. Testosterone is at high levels in winter, spring and summer and drops to a low concentration in autumn.
