Cultural gems linked open data: Mapping culture and intangible heritage in European cities.

The recovery and resilience of the cultural and creative sectors after the COVID-19 pandemic is a current topic with priority for the European Commission. Cultural gems is a crowdsourced web platform managed by the Joint Research Centre of the European Commission aimed at creating community-led maps as well as a common repository for cultural and creative places across European cities and towns. More than 130,000 physical locations and online cultural activities in more than 300 European cities and towns are currently tracked by the application. The main objective of Cultural gems consists in raising a holistic vision of European culture, reinforcing a sense of belonging to a common European cultural space. This data article describes the ontology developed for Cultural gems, adopted to represent the domain of knowledge of the application by means of FAIR (Findable, Accessible, Interoperable, Reusable) principles and following the paradigms of Linked Open Data (LOD). We provide an overview of this dataset, and describe the ontology model, along with the services used to access and consume the data.

Energy communities in the transition to a low-carbon future: A taxonomical approach and some policy dilemmas.

In calls for transition to a society in which energy production is based on renewable sources, a fundamental role is increasingly assigned to so-called 'energy communities'. The term 'energy communities' is, however, used to denote a range of different circumstances thus risking overly simplifying the phenomenon. The intention of this article is to discuss what these communities really are or could be. The article is structured into five sections. The first section introduces the main topic. The second section clarifies the use of the term community, and propose an energy community taxonomy (we consider two pairs of options which generate a four-cell matrix: a first distinction can be made between "place-based" and "non-place-based" communities on the basis of a potential correspondence between the community and a specific area; a further difference is that between communities which take shape solely for energy purposes and those with a range of objectives including goals encompassing shared management of energy systems - in this sense, we can distinguish between "single-purpose" and "multi-purpose" communities). The third section considers certain examples which test and exemplify this taxonomy. The fourth section discusses the most significant features which have emerged and considers the main implications (e.g. policy implications). The fifth section concludes by encouraging further critical debate.

Platelet microparticles sustain autophagy-associated activation of neutrophils in systemic sclerosis.

Endothelial cell damage and platelet activation contribute to sustained vasculopathy, which is a key clinical characteristic of systemic sclerosis (SSc), also known as scleroderma. Microparticles released from activated platelets in the blood of SSc patients (SSc-microparticles) are abundant and express the damage-associated molecular pattern (DAMP) HMGB1. SSc-microparticles interacted with neutrophils in vitro and in immunocompromised mice and promoted neutrophil autophagy, which was characterized by mobilization of their granule content, enhanced proteolytic activity, prolonged survival, and generation of neutrophil extracellular traps (NETs). Neutrophils migrated within the mouse lung, with collagen accumulation in the interstitial space and the release of soluble E-selectin by the vascular endothelium. Microparticle-neutrophil interaction, neutrophil autophagy and survival, and generation of NETs abated in the presence of BoxA, a competitive inhibitor of HMGB1. Consistent with these results, neutrophils in the blood of SSc patients were autophagic and NET by-products were abundant. Our findings implicate neutrophils in SSc vasculopathy and suggest that platelet-derived, microparticle-associated HMGB1 may be a potential indicator of disease and target for novel therapeutics.