[Effects of coffee consumption on salivary cortisol and alpha amylase in young adults]. / Efectos del consumo de café sobre el cortisol y la alfa-amilasa salival en adultos jóvenes.

Objective: The purpose of this study was to determine the effects of coffee consumption on salivary cortisol (sCort) and alpha amylase (sAA) in young adults. Materials and methods: Sixty healthy university students, habitual coffee consumers, participated in this descriptive observational study. Participants were divided into three groups: G1 low consumption (≤ 2 cups of coffee per day, n = 20), G2 moderate consumption (2-5 cups of coffee per day, n = 20), and G3 high consumption (>5 cups of coffee per day, n = 20). Saliva self-collection was in the morning (6:30-7:30 AM) and at night (08:00-09:00 PM). sCort was analyzed using chemiluminescence and sAA activity by kinetic method. Statistical analysis of the data was performed using Student's t-test and analysis of variance. Results: The sample consisted of 30 women and 30 men, aged between 20 and 35 years. In all groups, sCort values were higher in the morning (AM 0,29 ± 0,19 vs. PM 0,09 ± 0,05 µg/dl, p < 0.0001). In contrast, sAA levels were higher in the night (PM 160,16 ± 60,42 vs. AM 32,79 ± 12,98 U/ml, p < 0.0001). No significant differences were detected, in the contents of Corts and AAs, between the groups. Conclusion: : Coffee consumption, in non-stressful conditions, did not alter levels and patterns of sCort and sAA in young adults.

[Salivary cortisol concentrations according to gender in the different stages of human development. A review of the literature]. / Concentración de cortisol salival con un enfoque de género en las diferentes etapas del desarrollo humano. Una revisión de la literatura.

Salivary cortisol secretion (Corts) is an individual adaptation reflex to internal / external stressors, which involves several biological and social factors. The aim of this study was to perform a review on variations in Corts concentrations in relation to biological differences of sex and gender socialization in the different stages of human development. MEDLINE / PubMed and Google Scholar were used to search for scientific evidence. 20 original English-language articles published from 2010-2020 were selected, including clinical trials and observational studies. The relationship between Corts and gender was historically discussed considering evolutionary and biological aspects. However, it cannot be explained as a cause-effect view and depends on unique sociocultural factors, which in sensitive periods of human development alter the hypothalamic-pituitary-adrenal axis and condition coping with stress.