[The role of sleep apnea in the pathogenesis of cardio-pulmonary insufficiency in patients with chronic obstructive bronchitis]. / O roli nochnogo apnoé v patogeneze legochno-serdechnoi nedosta- tochnosti u bol'nykh khronicheskim obstruktivnym bronkhitom.

Continuous registration of breath, ECG, O2 tension was carried out in sleeping chronic obstructive bronchitis (COB) patients (n-46). Sleep apnea was detected in 19 of them. It was found that signs of pulmonary insufficiency in association of COB and sleep apnea occur significantly earlier. No correlation was observed between the severity of bronchial obstruction and pathological sleep apnea. The discussion covers mechanisms of pulmonary and cardiac insufficiency onset in COB patients with sleep apnea, therapeutic responses to long-term oxygen treatment and introduction of artificial respiratory control.

[Microcirculatory changes in respiratory insufficiency]. / Izmeneniia mikrotsirkuliatornogo krovoobrashcheniia pri dykhatel'noi nedostatochnosti.

The paper describes the results of study of 71 patients with chronic diseases of the lungs. The methods of investigation were directed at eliciting changes in extravascular, vascular and intravascular factors of the microcirculatory system. Considerable disorders of the microcirculation have been found in respiratory insufficiency and their dependence of the stage of insufficiency. Comparison of the degree of microcirculatory shifts with the gaseous composition of the blood and the acid-base balance has been made. The stages of microcirculatory changes run parallel to the severity of respiratory insufficiency, and the causes leading to pathology of microcirculation in respiratory insufficiency are multifactorial in character, the main being changes in the gaseous composition of the blood.