[Laparoscopic subtotal colectomy with mesorectumectomy in case of Hirschsprung's disease in adults].

Hirschsprung's disease in adults is a rare pathology. It was suggested the new method of Hirschsprung's disease surgical treatment in adults: distal subtotal colectomy, mesorectumectomy, appendectomy with ceco-anal anastomosis. The successful experience of laparoscopic subtotal colectomy, mesorectumectomy for this pathology is described in the article.

[The role of double-ballon enteroscopy in diagnosis and treatment of polypoid syndromes of gastrointestinal tract].

It was done 192 double-ballon enteroscopies in 141 patients at the period from March 2009 to March 2012. Epithelial benign tumors were detected in 10 (7.1%) patients with congenital polypoid syndromes. Endoscopic excision of polyps was done in 6 patients including 1 case with laparoscopic-assisted technique. Urgent open surgeries were performed before this in 4 patients with Peutz-Jeghers' syndrome and invaginated small bowel obstruction. The authors consider that double-ballon enteroscopy is highly informative diagnostic and treatment method in case of small bowel diseases. It allows to diagnose and to treat epithelial tumors on the early stage. Also it could help to avoid complications development and disability of patients.

Biological production and eutrophication of Baltic Sea estuarine ecosystems: the Curonian and Vistula Lagoons.

The long-term data on the temporal and spatial changes of chlorophyll and nutrients concentrations, phytoplankton biomass, primary production and mineralization of organic matter in the Curonian and Vistula Lagoons were analyzed using seasonal data to 1994 and monthly data to 2007 at 9-12 stations. A comparison with hydrological (water temperature, salinity, water exchange) and chemical parameters indicate the main abiotic factors which influence the level of biological production and the trophic state of lagoons. Most of the Curonian Lagoon showed the strong summer warming-up of water (higher 20 degrees C) combined with freshwater conditions, slow-flow velocity and high concentrations of phosphorus which creates conditions for hyperblooms of Cyanobacteria. The biological production of the Vistula Lagoon is below the potentially possible level as the hydrodynamic activity (high-flow velocity) and brackish water prevent the intensive development of Cyanobacteria. The Curonian Lagoon may be considered as hypertrophic water body whereas the Vistula Lagoon is a eutrophic water body.

[Morphological aspects of diagnosis of acute opiate poisoning]. / Morfologicheskie aspekty diagnostiki ostrykh otravlenii opiatami.

Clinical anatomical analysis, forensic chemical, morphological, bacteriological, and immunological investigations of material from 62 subjects dead from acute poisoning with opiates before hospitalization (31 cases) and in hospital (31 cases) were carried out. Organ and tissue lesions typical of opiate poisoning were detected. The outcome of acute poisoning with opiates is largely determined by severe dystrophic and inflammatory processes in organs and tissues, typical of narcomaniacs.

[Primary meningeal sarcomatosis of the brain and spinal cord with multiple tumor nodes]. / Pervichnyi meningeal'nyi sarkomatoz golovnogo i spinnogo mozga s mnozhestvennymi opukholevymi uzlami.

One case of this rare tumor diagnosed clinically in a female of 24 is reported. Cell composition was the same in both brain and spinal cord. There was a combination of a diffuse pattern of tumor cell arrangement with a formation of nodules and the spread of tumour cells along the perivascular spaces into the brain and spinal cord, along the endoneurium to the cranial and spinal nerve roots and metastasizing through the liquor system.

[Angiodysgenetic necrotizing myelopathy (the Foix-Alajouanine syndrome)]. / Angiodisgeneticheskaia nekrotiziruiushchaia mielopatiia (sindrom Fua--Alazhuanina).

One observation of a rare disease--angiodysgenetic necrotizing myelopathy--in a 50-year-old patient is described. The diagnosis was established at necropsy and did not confirm suspected spinal cord tumor and myelitis. The disease is angiodysplasia with resulting necrotizing myelopathy. Large dysplastic intra- and extramedullary vessels with a disturbed wall permeability, vascular malformations and necrotic foci in the spinal cord are characteristic for this condition.

[Determination of pyrimidine nucleotide sequences of DNA]. / Opredelenie pirimidinovykh nukleotidnykh posledovatel'nostei DNK

A modification of the Burton method for determination of pyrimidine nucleotide blocks (isopliths) of DNA, providing a higher yield of large-sized nucleotide isopliths, is described. The amount of side products (interisopliths) does not exceed their amount upon DNA hydrolysis according to the Burton method. Another advantage of the technique recommended is a considerable shortening of hudrolysis time (20 min instead of 18 hours). The modification described has been successfully used to determine the pyrimidine nucleotide blocks of some warm-blooded animals DNAs. It has been found that the DNA of animals with higher sensitivity to ionised irradiation contains more oligothymidylic sequences as compared to the DNA of animals, less sensitive to irradiation.