1.
Biull Eksp Biol Med
; 122(7): 40-2, 1996 Jul.
Artigo
em Russo
| MEDLINE
| ID: mdl-9303697
Assuntos
Plaquetas/efeitos dos fármacos , Bloqueadores dos Canais de Cálcio/farmacologia , Cálcio/metabolismo , Calmodulina/antagonistas & inibidores , Cadeias Leves de Miosina/metabolismo , Piperidinas/farmacologia , Inibidores da Agregação Plaquetária/farmacologia , Plaquetas/fisiologia , Humanos , Técnicas In Vitro , Fosforilação/efeitos dos fármacos , Sulfonamidas/farmacologia , Verapamil/farmacologia
2.
Ukr Biokhim Zh (1978)
; 63(6): 20-5, 1991.
Artigo
em Russo
| MEDLINE
| ID: mdl-1816678
RESUMO
Seven cardioactive polypeptides have been identified in the precardiac and auricular regions of the bovine heart. Those polypeptides were studied for their action on the function of isolated preparations of the vessel. It has been found that compounds isolated from the precardiac region induce different (20-55%) relaxation of smooth muscles in a strip of the aorta of rabbit. The possibility of formation of endogenic cardioactive compounds in model experiments imitating processing is studied. The data obtained permit assuming and alternatively explaining existence of multiple forms of the mentioned compounds as a result of partial proteolytic splitting of larger molecules.