Regenerative Potential of Spinal Ganglion Neurons During Topical Administration of Platelet-Enriched Blood Plasma Into the Skin Wound.

We studied the reactions of spinal ganglion neurons accompanying regeneration of the skin wound complicated by S. aureus sp. infection. The appearance of neuron groups with different morphofunctional changes was noted: reversible dystrophic and compensatory reactions and irreversible degenerative changes. The proportion of small B neurons was higher than the proportion of large type A neurons at all terms of the experiment. Application of plateletrich plasma to the wound after preliminary hydroimpulsive treatment considerably reduced cell destruction and stimulated regenerative effects in neurons starting from day 7 of the experiment. Application of platelet-rich plasma without hydroimpulsive treatment decelerated wound regeneration and increased the number of destructively changed neurons even in comparison with spontaneous wound healing. Close correlations between protein synthesis markers and stages of the wound process and its characteristics were revealed.

Regeneration Potential of Lymphoid Tissue of Small Intestine in Mice after Exposure to Low-Intensity Radiation.

Number and size of aggregated lymphoid nodules in the small intestine of mice exposed to radiation using a γ-irradiation unit GOBO-60 with 137Cs source were measured using the methods of visual microscopy and morphometry. Morphological status of the nodules was estimated on days 4, 28, 60, and 90 after the exposure. Significant changes were observed in the lymphoid system of the small intestine after exposure to low-intensity radiation. The size of aggregated lymphoid nodules decreased and the relative number of cells with degenerative changes increased. Regenerative processes were observed as soon as on day 4 of the rehabilitation period. However, the number and sizes of aggregated lymphoid nodules (length, width, and section area), and the ratio of lymphoid nodules with germinal center were still lower than in the control. The number of cells forming lymphoid interstitial plaques was close to the control on days 28-90 of the rehabilitation process.

[Main indicators of physical development and somatotypological features of men in older age groups].

The article presents the anthropometric indicators of 210 old age men (aged 60-74 years), 108 elderly men (aged 75-90 years) and 125 long-liver men (aged 90-98 years) of the Slavic ethnic group, living in Moscow and Moscow region. Significant differences in basic anthropometric parameters have been established in body weight and body mass index between the three age groups. Average values of body height in elderly men were lower by 0.6% (p>0.05), and in long-liver men were significantly lower by 4.6% than in old age men. Diameters did not have statistically significant differences in all age groups. Averages values of all circumferences of available limbs significantly differed in three age groups, averages values of waist and thigh circumference significantly differed only in the group of long-liver men and old age men. Averages values of breast circumference were not statistically different in three age groups. Average values of all eight skin-fat folds were significantly lower in long-liver men compared with old age men, whereas in elderly men only skin-fat folds of shoulder front and back, forearms, chest and lower leg were significantly less than in old age men. Somatotypological analysis revealed a different frequency of somatotype occurrence and the prevalence of 3 main types among men of older age groups (old age men, elderly men, long-liver men) - chest (18.5, 26.2 and 28.4%), abdominal-muscle (20.1, 15.4 and 16.8%) and abdominal (20.8, 22.2 and 19.4% respectively). Also the peculiarities of the component body composition of men of older age groups were revealed. Body composition analysis revealed a decrease in the average indicators of the absolute content of bone, fat and muscular body components from the old age to the period of longevity (long-liver men). Absolute content of bone tissue in elderly men (7.9±0.3 kg) didn't differ and in the period of longevity (6.8±0.2 kg) was less by 1.18 fold (p<0.05) than in old age men (8.0±0.3 kg). Absolute amount of body fat tissue in elderly men (16.1±1.2 kg) was less by 1.09 fold (p<0.05) and in long-liver men (12.5±1.0 kg) was less by 1.41 fold (p<0.05) than in old age men (17.6±1.4 kg). Absolute amount of body muscle tissue in elderly men (18.2±0.3 kg) was less by 1.17 fold (p<0.05) and in the period of longevity (16.3±0.2 kg) was less by 1.31 fold (p<0.05) than in old age men (21.3±0.2 kg). Average relative indicators of the major body components with aging undergo a number of changes, which are reflected in the reduction of quantity of bone and muscle tissue and increasing rates of adipose tissue.

[Characteristics of some indicators of physical development and frequency of occurrence of certain somatotypes of women in older age groups].

The article presents the anthropometric parameters of 251 elderly women (75-90 years) and 125 long-liver women (90-98 years) of the Slavic ethnic group, living in Moscow and Moscow region. Significant differences in basic anthropometric characteristics between two age groups have been demonstrated. Average values of body weight and height, circumferences and quantities of skin-fat folds were significantly lower in long-liver women in compare with representatives of the elderly, whereas diameters had no statistical significant differences. Somatotypological analysis revealed a frequency of occurrence of different somatotypes and prevalence of the three main types among elderly and long-liver women - asthenic (32.2-34.0%), pyknic (29.3-30.0%) and europlastic (20.0-21.2%) somatotype. Some features of body composition characteristics of elderly and long-livers women have been demonstrated as well. Estimated absolute amount of bone compartment did not differ in two women groups, while relative amount of bone compartment in elderly women (15.30±0.21%) was lower by 1.11 fold (p<0.05) than in long-liver women (17.05+±0.17%). The content of fat and muscular body compartment was significantly (p<0.05) lower in long-liver women as compared with the elderly women. The absolute amount of fat body compartment in long-liver women was 9.15±1.22 vs 13.13±0.49 kg in elderly women, the relative amount of fat body compartment - 14.39±0.26 vs 18.04±0.05%; the absolute amount of muscular body compartment - 23.04±0.26 vs 28.06±0.47 kg, the relative amount of fat body compartment - 36.22±0.15 vs 38.54±0.16%.

[Biochemical characteristics of Yersinia enterocolitica strains isolated in the Maritime Territory]. / K biokhimicheskoi kharakteristike shtammov Yersinia enterocolitica, vydelennykh v Primorskom krae.

The detailed study of 179 strains, considered to be typical and atypical representatives of Y. enterocolitica upon their isolation, has been carried out. Of these, 129 strains have been found to belong to Y. enterocolitica with their typical biochemical properties and 50 strains, to new Yersinia species. The ecological sources of all the isolated strains are indicated. The necessity of the thorough epidemiological, clinical and laboratory study of the etiological role of Yersinia in acute intestinal diseases in humans is pointed out.