RESUMO
BACKGROUND: The rapid and widespread of COVID-19 has caused distress and havoc among people in all walks of life. Such impact has been more pronounced among HCWs. We sought to examine how health care workers (HCWs) knowledge about COVID-19 and perceived anxiety can influence preventive practices. MATERIALS AND METHODS: In this cross-sectional study a multiple regression analysis was applied to examine the relationship between knowledge, anxiety, and preventive practices among 267 participants work in different settings in a variety of health care organizations in different regions in Saudi Arabia. To estimate potential associations, a multiple regression analysis was applied. Standardized beta-coefficients and their 95% confidence intervals were estimated to examine the outcome variable and the predictors' associations. RESULTS: Our findings shows that HCWs had high levels of knowledge about COVID-19, perceived anxiety, and preventive practices. In examining the relation between HCWs characteristics and their knowledge about COVID-19, older HCWs have been shown to have higher knowledge compared to younger HCWs. Finally, the model to estimate the impact of knowledge about COVID-19 and perceived anxiety on preventive practice showed that both have a significant impact. CONCLUSIONS: HCWs tendency to adhere to preventive practices is related to their levels of knowledge and perceived anxiety. Such a relationship can inform administrators and policymakers in the health care field to design health promotion campaigns to ensure all HCWs are aware of the nature of communicable diseases and the risk they might entail.
RESUMO
Despite the fact that proton pump inhibitors (PPIs) are one of the most prescribed medications, several epidemiological studies have reported many adverse effects related to their long-term usage. Nevertheless, there were inconsistent findings in the literature with regard to PPI use and bone mineral density (BMD) change. The aim of this systematic review and meta-analysis is to evaluate the association between the use of PPIs and change in BMD. The PubMed/MEDLINE, EMBASE, Cochrane and CINAHL databases were searched up to March 2019. Ten studies fulfilled the eligibility criteria (4761 cases and 30,809 controls), from which the mean difference and mean annualized percent change in BMD were pooled using RevMan 5.3.5 The results showed no statistically significant association between PPI users and non-users in mean annualized percent change in BMD (0.06; 95% CI -0.07, 0.18) with moderate heterogeneity (I2: 63%). There was a statistically significant reduction in the mean BMD difference among PPI users (-0.03; 95% CI -0.04, -0.01) with no substantial heterogeneity (I2: 26%). This meta-analysis reported inconsistent results regarding the use of PPIs and BMD loss. Thus, the effect of PPIs on BMD needs to be elucidated by other studies, and healthcare providers should prescribe PPIs with caution considering their unfavorable consequences on bone health.
RESUMO
BACKGROUND: Amphetamine-type stimulants (ATS) are the most commonly used illicit drugs in Saudi Arabia. Frequency and outcome of ATS-related cardiovascular (CV) complications in the Saudi community have not been previously studied. AIM: We aimed to determine the incidence and the clinical outcomes of CV complications among individuals with amphetamine-positive urine drug screening (APUDS) tests admitted to a tertiary care facility in Riyadh, Saudi Arabia. METHODS: Retrospective review of consecutive cases with APUDS and concurrently positive cardiac biomarkers admitted to King Abdul-Aziz Medical City in Riyadh, Saudi Arabia, between January 2006 and December 2013. The laboratory database was queried to identify patients with positive APUDS and abnormal cardiac biomarkers. Clinical data were extracted from the electronic medical records. RESULTS: A total of 7450 urine drug screening tests were performed during the study period, out of which 720 (9.6%) were positive for ATS (APUDS group). Forty-two cases in the APUDS group were documented to have CV complications. All cases were men with a median age of 39 years (range, 21-60 years). Acute coronary syndrome/myocardial infarction was the most frequent clinical presentation (n = 31, 74%), predominantly in the form of ST-elevation myocardial infarction. Other less frequent complications included myopericarditis, cardiomyopathy, and arrhythmia. Coronary procedures were performed in 30 cases. Median hospital stay was 5 days (range, 1-28 days) and in-hospital mortality was 7.2%. CONCLUSION: APUDS is frequently encountered in young Saudi men presenting to the emergency department of our institution. Individuals with APUDS are at increased risk of CV complications and in-hospital mortality. The most frequent APUDS-related CV complication is acute coronary syndrome.
