[Endovascular papillary angioendothelioma]. / Endovaskuliarnaia papilliarnaia angioéndotelioma.

One case of a rare vascular tumor which occurs mainly in the childhood is presented. The tumor has a tendency to recurrence and metastases into the regional lymph nodes in spite of a relatively mature structure.

[Atypical adenomatous hyperplasia of the lung]. / Atipichnaia adenomatoznaia giperplaziia legkikh.

Clinicomorphological analysis was performed in 12 cases of atypical adenomatous hyperplasia of the lung (AAH). This is the proliferative lesion consisting of atypical epithelial cells along the alveolar septa which are found incidentally during pathologic examination of the lung resected because of cancer. We studied morphological and biological characteristics of AAH cells including cytodifferentiation, proliferative activity, tumor-suppressor genes. Our review of the studies of AAH revealed that AAH is alveolar intraepithelial dysplasia and a precursor of lung adenocarcinoma. AAH is an important lesion corresponding to a step in carcinogenesis for peripheral lung adenocarcinomas.

[Role of induction chemo- and radiotherapy in the treatment of locally advance breast cancer]. / Znachenie induktsionnoi luchevoi i khimioterapii v lechenii mestnorasprostranennogo raka molochnoi zhelezy.

336 patients with locally-advanced breast cancer underwent neoadjuvant chemotherapy or chemoradiotherapy. Increase in T- and N-indices (change of stage after neoadjuvant chemotherapy) proved an important prognostic factor. Survival rates correlated with clinical effect and dropped as it diminished. This tendency was clear in both groups. There was no relationship between stage and overall and disease-free survival rates at early stages but later they declined as T- and N-indices decreased.

[Cystic epithelioma in the epidermal cyst]. / Kistoznaia epitelioma v epidermal'noi kiste.

A case of skin tumor-cystic epithelioma is reported. Differential-diagnostic features of its distinction from squamous-cell carcinoma are given.

[Carcinoid tumors of the lung]. / Kartsinoidnye opukholi legkikh.

Detailed cytological, histological and electron microscopic characteristics of pulmonary carcinoid tumors are listed on the basis of surgical clinic material. Various variants of the carcinoid tumors structure, their differential diagnosis are presented.

[Osteochondroplastic tracheobronchopathy]. / Osteokhondroplasticheskaia trakheobronkhopatiia.

14 cases of osteochondroplastic tracheobronchopathy (OT) are studied histologically. The disease is characterized by formation of cartilage and bone tissue in the submucosa of the trachea and bronchi outside their own cartilagenous carcass. Its histogenesis is not clear and is attributed to chronic bronchitis, specific inflammation, dysembryogenetic alterations, endocrine disorders, environmental and occupational hazards, amyloidosis of the trachea. The process is localized in the trachea and bronchi as an isolated and rarely as a diffuse lesion. Morphologically, normal or atrophic mucous membrane is observed, at some places with a squamous metaplasia. Areas of cartilage with calcium deposits and foci of bone having a trabecular structure with formation of spongious bone tissue, sometimes with bone marrow, were found.

[Carcinoid of the kidney]. / Kartsinoid pochki.

Rare location of carcinoid tumour in the kidney is reported. The diagnosis was established on the basis of histological and ultrastructural investigation.

[The degree of tumor vascularization as a prognostic factor of the efficacy of neoadjuvant polychemotherapy in breast cancer]. / Stepen' vaskuliarizatsii opukholi kak prognosticheskii faktor éffektivnosti neoad''iuvantnoi polikhimioterapii pri rake molochnoi zhelezy.

A procedure for obtaining microcirculation coefficient is described. It is based on the phenomenon of formation of a focus of radionuclide hyperfixation on scintigrams of tumor area due to embolization of its arterioles and precapillaries with radionuclide. The method was used in 26 breast cancer patients before neoadjuvant chemotherapy. A direct correlation between the microcirculation coefficient and degree of tumor-induced pathomorphosis of tumor cells was established. The coefficient values proved more or less predictive of tumor response to chemotherapy.

[The fibroepithelial variant of basal-cell skin cancer (Pincus' "premalignant" fibroepithelioma)]. / Fibroépitelial'nyi variant bazal'nokletochnogo raka kozhi ("predzlokachestvennaia" fibroépitelioma Pinkusa).

12 cases of the basal cell carcinoma fibroepithelial variant are studied morphologically. This variant of basal cell carcinoma is erroneously diagnosed as adenoid variant of seborrheic keratosis, tubular syringoadenoma or the reverse. Main differential-diagnostic criteria allowing to distinguish a fibroepithelial variant of basal cell carcinoma from an adenoid variant of seborrheic keratosis are multicentric foci of superficial basalioma as well as the absence of hyperkeratosis and intraepithelial carcinomatous cysts. The tumour differs from tubular syringoadenoma by the lack of tubular structures with two-layer epithelial lining and cysts with signs of secretory activity.

[Epidermoid thymoma--a variety of thymus gland cancer]. / Epidermoidnaia timoma--raznovidnost' raka vilochkovoi zhelezy.

Epidermoid thymoma was referred to thymal malignancies after an evaluation of the data on its clinical course and microscopic structure. This tumor may be diagnosed preoperatively on the basis of an analysis of clinico-roentgeno-endoscopic data and findings of a cytological, histological and electron-microscopic examinations.

[Pathological anatomy of thymus gland tumors]. / Patologicheskaia anatomiia opukholei vilochkovoi zhelezy.

The paper presents detailed morphological characteristics of 31 thymomas and 25 microscopically similar neoplasias of the anterior mediastinum (carcinoid, seminoma, lymphogranulomatosis, angiofollicular lymphoma, etc). The term "thymoma" is determined as a tumour consisting of two components: mandatory epithelial one and lymphocytes. The diversity of the morphological picture of thymomas is determined mainly by the variability of the epithelial component. The special features of the ultrastructural organization of thymomas (the presence of desmosomes, tonofibrils and basal membrane) were revealed which facilitate the differential diagnosis of the anterior mediastinum tumours.