RESUMO
Mammary carcinoma arising in ectopic breast tissue is an uncommon occurrence. Most reported cases have involved ductal carcinoma, but other types, such as medullary, papillary, and lobular carcinomas, have been described. For pathologists, the diagnosis of mammary carcinoma arising in ectopic breast tissue can be difficult, especially in the axilla, where carcinoma of adnexal origin must be excluded. We describe a 46-year-old woman who developed invasive (juvenile) secretory carcinoma in ectopic right axillary breast tissue and micrometastatic carcinoma in an ipsilateral axillary lymph node. The carcinoma arose in a right axillary mass that had been present for 8 years, from which she had secreted fluid during prior breast-feeding. To our knowledge, this is the first report of secretory carcinoma arising in axillary breast tissue to be documented in the current literature.
Assuntos
Axila , Neoplasias da Mama/patologia , Mama , Carcinoma/patologia , Coristoma/patologia , Complicações Neoplásicas na Gravidez , Biópsia , Neoplasias da Mama/metabolismo , Neoplasias da Mama/cirurgia , Carcinoma/metabolismo , Carcinoma/cirurgia , Quimioterapia Adjuvante , Feminino , Humanos , Excisão de Linfonodo , Metástase Linfática , Pessoa de Meia-Idade , GravidezRESUMO
Diffuse angiomatosis of the extremities is a rare condition characterized by extensive or multifocal benign mass-forming vascular lesions involving multiple tissue planes; histologically, adipose and fibrous tissue are admixed with vascular elements that vary from capillary proliferations to large vessels that are often structurally abnormal. Although diffuse angiomatosis most likely represents a hamartomatous form of arteriovenous malformation, it behaves clinically as a benign but slowly progressive and unresectable neoplasm. We describe a case of diffuse angiomatosis of the lower extremity that presented clinically as a soft-tissue sarcoma.
Assuntos
Angiomatose/diagnóstico , Perna (Membro)/irrigação sanguínea , Sarcoma/diagnóstico , Neoplasias de Tecidos Moles/diagnóstico , Angiomatose/patologia , Diagnóstico Diferencial , Feminino , Humanos , Perna (Membro)/patologia , Masculino , Pessoa de Meia-Idade , Sarcoma/patologia , Neoplasias de Tecidos Moles/patologiaRESUMO
Multiple manifestations of disordered or arrested cardiac muscle development are reported in a 14-year-old boy with clinical evidence of heart disease. These include persistent noncommunicating intramyocardial sinusoids, anomalous right ventricular muscle bands, muscular deficiency of ventricular septum, and papillary muscle underdevelopment. To our knowledge, this complex of findings has not been previously described.
Assuntos
Cardiomiopatias/congênito , Cardiopatias Congênitas/patologia , Miocárdio/patologia , Adolescente , Encéfalo/patologia , Cardiomiopatias/patologia , Endocárdio/anormalidades , Endocárdio/patologia , Comunicação Interventricular/patologia , Ventrículos do Coração/anormalidades , Ventrículos do Coração/patologia , Humanos , Rim/patologia , Masculino , Valva Mitral/anormalidades , Valva Mitral/patologia , Músculos Papilares/anormalidades , Músculos Papilares/patologiaRESUMO
Autopsy findings in a case of widely disseminated lobular breast carcinoma showed an unusual histiocytoid appearance in metastases to the uterus and parathyroid gland. This morphology for breast carcinoma has been previously reported in eyelid metastases. Recognition of this pattern in other metastatic sites has important diagnostic and therapeutic implications. Problems might have arisen if the polypoid uterine mass had been the presenting lesion during life. We also review the occurrence of metastatic breast carcinoma in the uterus and parathyroid gland.
Assuntos
Neoplasias da Mama/patologia , Carcinoma/patologia , Adulto , Neoplasias da Mama/terapia , Carcinoma/terapia , Terapia Combinada , Feminino , Humanos , Neoplasias das Paratireoides/secundário , Neoplasias Uterinas/patologia , Neoplasias Uterinas/secundárioRESUMO
A newborn infant with hydrocephalus was found to have residua of subependymal-intraventricular hemorrhage and associated obliterative arachnoiditis. This process is well known in the postnatal period but not as an in utero event. The present article documents antenatal intraventricular hemorrhage as a cause of hydrocephalus.