RESUMO
Background: Prediabetes is a serious health condition which can be treated with changes to lifestyle behaviour. It is a significant warning sign of being at high risk of developing type 2 diabetes. This study aims to assess knowledge of prediabetes and its associated risk factors in the community of Al-Madinah, Saudi Arabia (SA). Methods: A cross-sectional study was conducted among adult respondents in Al-Madinah in 2022. A sample size of 397 participants completed a validated self-administrated survey and data were analysed using descriptive statistics (numbers, percentages, mean and standard deviation). Results: Of the 397 participants who responded to the survey, 56.7% were aged between 21 and 25 years old, with more than half (51.9%) being male and the majority being more educated (72%). Among the participants, 14.1%, 34.3% and 51.5% had a high, moderate and poor knowledge of prediabetes, respectively. Overall, there was a statistically significant association between age (>25 years old) (p = 0.003), gender difference (p = 0.006), and prediabetes knowledge. Conclusion: Knowledge of prediabetes is important in the prevention of type 2 diabetes. The population of Al-Madinah demonstrated a low level of prediabetes knowledge; therefore, the design and implementation of community-based intervention programmes with an emphasis on raising prediabetes awareness is crucial. Policymakers, organisations and partnerships will be required to develop a well-designed and effective programme.
RESUMO
Millet is a grain high in polyphenols and antioxidants, which are bioactive compounds known to influence blood glucose response. The aim of this study was to compare the effect of finger millet muffin and wheat muffin on glycaemic response (GR), insulin response (IR), gastric emptying (GE) and satiety in healthy individuals and people with prediabetes. In a single-blind randomised controlled crossover trial at Oxford Brookes Centre for Nutrition and Health, fifteen healthy individuals and fourteen individuals with prediabetes were recruited between May and December 2017. The participants' GR (3 h), IR (3 h), GE (4 h) and satiety (4 h) were measured before and after the consumption of muffins. A mixed method ANOVA was used to compare GE and the incremental AUC (iAUC) for GR and IR between the participant groups and muffins. There was a significant interaction between participants and muffins on IR iAUC at 180 min (P = 0·042). A significant effect of muffins was found on the GR peak (P = 0·013). The millet muffin decreased the GR peak and IR iAUC compared with the wheat muffin in participants with prediabetes. A significant interaction between participants and muffins for GE ascension time Tasc (P = 0·017) was observed, with no effect of muffins on satiety AUC in the participant groups. This study suggested that polyphenol and fibre-rich finger millet may have the potential to influence the management of prediabetes.
