Natural products from ethnodirected studies: revisiting the ethnobiology of the zombie poison.

Wade Davis's study of Haitian "zombification" in the 1980s was a landmark in ethnobiological research. His research was an attempt to trace the origins of reports of "undead" Haitians, focusing on the preparation of the zombification poison. Starting with this influential ethnopharmacological research, this study examines advances in the pharmacology of natural products, focusing especially on those of animal-derived products. Ethnopharmacological, pharmacological, and chemical aspects are considered. We also update information on the animal species that reportedly constitute the zombie poison. Several components of the zombie powder are not unique to Haiti and are used as remedies in traditional medicine worldwide. This paper emphasizes the medicinal potential of products from zootherapy. These biological products are promising sources for the development of new drugs.

Intracultural variation in the knowledge of medicinal plants in an urban-rural community in the atlantic forest from northeastern Brazil.

This study assessed the intracultural knowledge of the use of medicinal plants in an urban-rural community in an Atlantic forest fragment in northeastern Brazil. We examined the importance of native and exotic species and the effects of gender and age on that knowledge. We also compared data obtained from different groups of informants (local experts and general community). We conducted 194 interviews between June 2007 and January 2008, using the freelist technique and semistructured forms to collect ethnobotanical data. Information obtained from the community was compared with that from six local experts who participated in a survey in 2003. From a total of 209 ethnospecies, exotic and herbaceous plants presented higher richness. With respect to the number of citations, women and older informants were shown to know a higher number of medicinal plants. Comparing knowledge of local experts with that of the general community, we noted that experts know a similar wealth of plant families and therapeutic indications, but the community knows a greater species richness. These results indicate that local experts may provide useful information for studies that search for a quick diagnosis of the knowledge of a given community.

Insights into the search for new drugs from traditional knowledge: an ethnobotanical and chemical-ecological perspective.

CONTEXT: The variety of pathways for the introduction of a species into the medical collection of traditional communities has led many researchers to question the processes of selection and the use of these resources. A better comprehension of these processes will allow us to understand the cultural dynamics that are related to traditional medical practices, as well as to provide us with new ways in which to facilitate the exploration of natural products. OBJECTIVE: This study aims to test the predictive power of the plant apparency hypothesis as it relates to medicinal plant selection by the rural communities of the Caatinga and the Atlantic Forest in northeast Brazil. MATERIAL AND METHODS: Initially, a survey of the medicinal plants used by these communities was conducted using semistructured interviews. Subsequently, data on the life strategies and the habits of each species were collected. More detailed data on the specific plant parts indicated in interviews were also collected. A phytochemical screening for seven classes of chemical compounds was carried out to test the predictions of the plant apparency hypothesis. RESULTS: The medicinal plants from the Caatinga (especially those that are considered to be trees in habit) have a strong ability to accumulate quantitative compounds, and these species are most likely to be plants with significant biological activity related to these compounds; the medicinal plants from the Atlantic Forest, on the other hand, tend to have a high occurrence of qualitative compounds, especially in herbaceous life forms. DISCUSSION AND CONCLUSION: It was concluded that the plant apparency hypothesis does not adequately explain the selection of medicinal plants in the two environments studied. Our findings highlight some important implications for bioprospecting that need to be further tested experimentally, and through systematic studies, in different regions.

A comparison of knowledge about medicinal plants for three rural communities in the semi-arid region of northeast of Brazil.

AIM: The aim of this research was to understand the importance of native and exotic plants in local medical systems in the Caatinga of the Brazilian northeast, and the influence of socio-economic factors on the acquisition of knowledge about these resources. METHODS: A total of 55 people were interviewed in three rural communities using free list and semi-structured interviewes. RESULTS: A total of 108 ethnospecies were reported, 99 of which were identified; 43 of these were preferred by informants. Most of the plants cited were exotic (51) but the difference in diversity among these plants and native plants (48) was not considered significant (p>0.05). The exotic plants were predominantly herbaceous and used to cure diseases that native plants did not seem to treat. There were no differences between men's and women's knowledge of the plants (p>0.05). However, for some communities, factors such as age and income were correlated with the number of citations and indications for plants, which suggested that older people and those with higher income levels had more knowledge about these properties. CONCLUSION: The data presented in this study showed the importance of exotic species in the region studied and demonstrated that plant knowledge can be perceived as a way to diversify options for medical treatment in the area.