Simulation of motor current waveforms in monitoring aortic valve state during ventricular assist device support.

Monitoring of aortic valve (AV) opening and closure during left ventricular assist device (LVAD) heart pump support is crucial in preventing AV abnormalities and remodeling caused by anomalous resirculation. In this study, simulations of LVAD motor current waveforms were undertaken to investigate AV response to rotary blood pump assistance, as well as to detect AV open and close status under heart failure conditions. A two-dimensional fluid-structure interaction finite-element model is presented to predict AV state during LVAD outflow. The data will be useful in the development of a pump speed controller for optimal management of pump outflow.

Simulation of aortic valve dynamics during ventricular support.

Existing commercially-used left ventricular assist devices (LVADs) make no attempt to automatically detect the aortic valve condition in their control methods to optimize ventricular assistance. An important design goal for LVADs is the ability to reliably and accurately detect aortic valve (AV) states during heart pump support that can cause harmful effects on AV structure and function. In this paper, we have investigated the correlation between AV performance and LVAD motor current as well as speed set points, simulating aortic valve blood flow, pressure, pump flow and LV mechanics using a simplified two-dimensional fluid-structure interaction finite-element model of AV dynamics.

Simulation of motor current waveform as an index for aortic valve open-close condition during ventricular support.

Monitoring of aortic valve (AV) opening and closure during heart pump support by a left ventricular assist device (LVAD) is crucial in preventing adverse events such as thrombus formation near the AV. In preventing adverse events such as thrombus formation near the AV. In this paper, simulations of LVAD motor current waveform were undertaken to evaluate its suitability for ascertaining aortic valve status. A two-dimensional fluid-structure interaction finite-element model is presented to predict AV closure during LVAD outflow, useful in the development of a pump speed controller.

Modeling aortic valve closure under the action of a ventricular assist device.

The support of a failing heart with pump devices has been an essential element in cardiac health care for several decades. It is therefore important to understand the left ventricular response to the pumping action of these devices when connected to the native heart. Furthermore, monitoring of aortic valve opening and closure is important in avoiding valve stenosis and thrombogenesis during pump support. This paper reports the first steps in simulating the effects of outlet pump pressure on aortic valve closure of the heart assisted by an implantable blood pump. A two-dimensional fluid structure interaction aortic valve model is presented with blood flow in left ventricular chamber using the Arbitrary Lagrangian-Eulerian Finite Element Method formulation to predict the AV closure during outflow of blood from the left ventricle into the left ventricular assist device (LVAD).