Buruli ulcers in a Spanish aid worker after a stay in Peru.

Buruli ulcer (BU) is a chronic and destructive infection of the skin and soft tissues caused by Mycobacterium ulcerans. Recently, population flows have triggered the appearance of several sporadic cases of BU in non-endemic countries. This represents a significant diagnostic challenge for clinicians and microbiologists. We describe the first case of BU imported to Spain. The patient was a Spanish woman who had stayed 5 months in the jungle of Peru.

Sarcoid-like reaction in a patient with uveitis and underlying cancer.

PURPOSE: Sarcoidosis is a granulomatous disease of unknown etiology. Occasionally, triggering causes are identified, such as neoplasms, and they are termed sarcoid-like reactions, which may appear in any sarcoidotic target tissue. Choroidal metastases appear as part of widespread metastatic disease or as the first suggestion of neoplastic disease. They can also be a part of the differential diagnosis of a spectrum of inflammatory eye diseases. We present a case in which a lung carcinoma, pulmonary and eye sarcoid-like reactions, and choroidal metastasis take place in the same patient. CASE REPORT: A 60-year-old male with a past history of pulmonary sarcoidosis and associated anterior uveitis was diagnosed with a lung carcinoma with no regional lymph nodes extension, so that the resection surgery was performed without additional systemic treatment. At the same time, he complained of visual acuity loss and pain in his right eye. An intense ocular inflammatory reaction and a choroidal mass compatible with metastasis were identified. A vitrectomy with an accompanied histological exam of the lesion was deemed inconclusive. Ocular symptoms progressively worsened showing mass growth, and as a result, an enucleation was performed and the histological study subsequently revealed metastasis from his lung carcinoma. CONCLUSION: Sarcoid-like reactions may be due to incipient malignancies. Any diagnosis of sarcoidosis requires ruling out other diseases that can produce secondary sarcoid-like reactions. In addition, any choroidal mass suggestive of metastasis requires exclusion of metastatic disease even in the absence of clinical signs indicating tumor extension.

Tendencia de la incidencia de cáncer de pulmón en un Área de Salud / Trends in Lung Cancer Incidence in a Healthcare Area

El presente estudio tiene por objetivo conocer la tendencia de la incidencia del cáncer de pulmón en el Área de Salud de León. Fueron incluidos los casos de cáncer de pulmón del Registro Hospitalario de Tumores del Centro Asistencial Universitario de León (CAULE), entre 1996-2010, con residencia en el Área de Salud de León. Se calcularon las incidencias trienales brutas y ajustadas a población mundial y europea. Se incluyeron 2.491 casos. Las tasas estandarizadas a población europea en varones ascendieron de 40,1 (trienio 1996-1998) a 61,8 (trienio 2005-2007), descendiendo a 54,6 casos nuevos por 100.000 (trienio 2008-2010). En el caso de las mujeres las tasas se triplicaron de 3,0 (trienio 1996-1998) a 9,2 casos nuevos por 100.000 (trienio 2008-2010). El cáncer de pulmón, a pesar de ser evitable, es un problema grave en el área de salud de León, siendo preocupante el incremento de la incidencia en mujeres

The aim of this study was to identify trends in the incidence of lung cancer in the Leon Healthcare Area. All cases of cancer among residents of the Leon healthcare catchment area listed in the hospital-based tumor registry of the Centro Asistencial Universitario de Leon (CAULE) between 1996 and 2010 were included. Gross incidence rates over 3-year intervals were calculated and adjusted for the worldwide and European populations. A total of 2,491 cases were included. In men, incidence adjusted for the European population rose from 40.1 new cases per 100,000 population (1996-1998) to 61.8 (2005-2007), and then fell to 54.6 (2008-2010). In women, incidence tripled from 3.0 (1996-1998) to 9.2 new cases per 100,000 (2008-2010). Although lung cancer is an avoidable disease, it is a serious problem in the Leon Healthcare Area. Of particular concern is the rising incidence among women

Trends in Lung Cancer Incidence in a Healthcare Area.

The aim of this study was to identify trends in the incidence of lung cancer in the Leon Healthcare Area. All cases of cancer among residents of the Leon healthcare catchment area listed in the hospital-based tumor registry of the Centro Asistencial Universitario de Leon (CAULE) between 1996 and 2010 were included. Gross incidence rates over 3-year intervals were calculated and adjusted for the worldwide and European populations. A total of 2,491 cases were included. In men, incidence adjusted for the European population rose from 40.1 new cases per 100,000 population (1996-1998) to 61.8 (2005-2007), and then fell to 54.6 (2008-2010). In women, incidence tripled from 3.0 (1996-1998) to 9.2 new cases per 100,000 (2008-2010). Although lung cancer is an avoidable disease, it is a serious problem in the Leon Healthcare Area. Of particular concern is the rising incidence among women.

Refractory pyoderma gangrenosum of the orbit and the lacrimal sac.

Pyoderma gangrenosum (PG) is a rare, idiopathic, necrotizing, and non-infectious ulcerating skin disease included among the neutrophilic dermatoses. It rarely affects the eye, orbit, and/or ocular adnexa. We describe one case of PG affecting both orbits and the lacrimal sac in a patient with Crohn's disease.

Hamartorna de la nasofaringe. Revisión y aportación de un nuevo caso

En el diagnóstico diferencial de los procesos expansivos localizados en el tracto sinonasal y la nasofaringe debemos tener presente a los hamartomas, aunque estos aparezcan muy raramente. En este artículo presentamos un nuevo caso de hamartoma adenomatoide epitelial respiratorio de la nasofaringe y revisamos la literatura (AU)

Tumor lipomatoso atípico de laringe versus liposarcoma de bajo grado / Larynx atypical lipomatous tumor versus low-grade liposarcoma

El nuevo concepto anatomo-patológico de tumor lipomatoso atípico debería englobar, según algunos autores, el de liposarcoma bien diferenciado, entre otros, creando, por tanto, una nueva clasificación para los tumores grasos. En este artículo, además de presentar un nuevo caso clínico del siempre inusual liposarcoma bien diferenciado de laringe, discutimos acerca de esta nueva terminología (AU)