Association of proximity to polluting industries, deprivation and mortality in small areas of the Basque Country (Spain).

BACKGROUND: The study is aimed at assessing social inequities in the location of polluting industries in the Basque Country, and at exploring if the effect on mortality of living near air polluting industries is modified by economic deprivation. METHODS: This is a cross-sectional ecological study that uses the census sections as analysis units. Mortality from all causes, lung cancer, respiratory diseases and ischaemic heart disease were studied. Ordinal logistic regression models were fitted to assess if proximity of census sections to polluting industries is associated with deprivation. Bayesian Poisson regression models were used to explore if the association between proximity to polluting industries and mortality is modified by socio-economic deprivation. RESULTS: Proximity to a polluting industry and deprivation are positively associated, showing a clear gradient across deprivation quintiles. In women, the risk associated with proximity to metal-processing industries grows as the deprivation of the area increases in the case of total and lung cancer mortality. In men, the interaction terms between proximity and deprivation are positive for total, ischaemic heart disease mortality, with a credibility level approaching 90%. High levels of deprivation are associated with greater risk of mortality, excepting lung cancer in women. CONCLUSION: There is a higher proportion of more deprived census sections around polluting industries in the Basque Country. Risks of mortality associated with proximity to polluting industries tend to be higher in more deprived areas.

[Exposure to lindane, other pesticides and organochlorines in the general population Barakaldo, Spain]. / Plaguicidas y PCBs en suero en población general de Barakaldo posiblemente expuesta al hexaclorociclohexano entre 1947 y 2002.

BACKGROUND: A plant of lindane in Barakaldo produced discharges of hexachlorocyclohexane (HCH). Closed in 1987 leaving inside 4500Tm; the problem was not solved until 2002. A judicial process required an epidemiological assessment of the possible contamination The aim of this study is to measure the degree of impregnation of the POPs in the nearby population. METHODS: Cross-sectional study conducted in 2008, 154 volunteers from three health centres in Barakaldo and 270 controls from Bilbao, Alonsotegi and Balmaseda. We measured serum levels of eight organochlorine pesticides, and seven polychlorinated biphenyls (PCBs). We used the χ² test to study the association between categorical variables and t test of Student to compare geometric means. Confounding factors were adjusted using a linear regression model. RESULTS: There was a detectable compound average of 6.3 per person. PCBs 52 and 101, α -HCH, ß-endosulfan and heptachlor epoxide could not be quantified; PCB 28, γ-HCH and p, p'-DDT were detected in 6.6, 0.9 and 8.05 % of subjects respectively and the ß-HCH, HCB, p, p'-DDE, and PCBs 118, 138, 153 and 180 in the 73.8, 87.3, 98.6, 59.2, 97.6, 98.6 y 98.6 % respectively. After adjusting for age, there were no higher levels of ß-HCH in Barakaldo than in controls, (beta = 0.02, SE = 0.07), or HCB, p, p'-DDE, PCB 118, PCB 138, PCB 153 and PCB 180. CONCLUSION: Six years after having solved the problem near to the factory and storage of HCH, there was no significantly higher levels of HCH, after adjustment for age.

Plaguicidas y PCBs en suero en población general de Barakaldo posiblemente expuesta al hexaclorociclohexano entre 1947 y 2002 / Exposure to lindane, other pesticides and organochlorines in the general population Barakaldo, Spain

Fundamentos: Una fábrica de lindano de Barakaldo generó múltiples vertidos de hexaclorociclohexano (HCH). Cerró en 1987 dejando 4.500Tm en su interior, no solucionándose el problema hasta 2002. Un proceso judicial requirió una evaluación epidemiológica de la posible contaminación. Este trabajo pretende medir la impregnación de COPs en la población cercana a la planta. Métodos: Estudio transversal, realizado en 2008, de 154 personas voluntarias de tres centros de salud de Barakaldo y 270 personas controles de Bilbao, Alonsotegi y Balmaseda. Se cuantificaron en suero ocho plaguicidas organoclorados y siete PCBs. Se utilizó la X² para contrastar la asociación entre variables categóricas y la t de Student para comparar medias geométricas. Se ajustaron factores de confusión mediante regresión lineal. Resultados: Se detectaron 6,3 compuestos de media detectables por persona. No se cuantificaron PCB 52 y 101, alpha-HCH, Beta-Endosulfán y Hep-tacloro-Epóxido; el PCB 28, γ-HCH y p,p’-DDT en un 6,6, 0,9 y 8,05%; y el Beta-HCH , HCB, p,p’-DDE y PCB 118, 138, 153 y 180 en el 73,8, 87,3, 98,6, 59,2, 97,6, 98,6 y 98,6% de los individuos, respectivamente. Ajustando por la edad no se observaron niveles más elevados en Barakaldo que en la población control de Beta-HCH (beta= 0,02; EE= 0,07), ni de HCB, p,p’-DDE, PCB 118, 138, 153 y 180. Conclusiones: Seis años después de resolverse el problema de los residuos en la población cercana a la fábrica de producción y de un almacenamiento masivo de HCH, no se observaron niveles significativamente mayores de HCH, tras su ajuste por edad(AU)

Bakcground: A plant of lindane in Barakaldo produced discharges of hexachlorocyclohexane (HCH). Closed in 1987 leaving inside 4500Tm; the problem was not solved until 2002. A judicial process required an epidemiological assessment of the possible contamination The aim of this study is to measure the degree of impregnation of the POPs in the nearby population. Methods: Cross-sectional study conducted in 2008, 154 volunteers from three health centres in Barakaldo and 270 controls from Bilbao, Alonsotegi and Balmaseda. We measured serum levels of eight organochlorine pesticides, and seven polychlorinated biphenyls (PCBs). We used the X² test to study the association between categorical variables and t test of Student to compare geometric means. Confounding factors were adjusted using a linear regression model. Results: There was a detectable compound average of 6.3 per person. PCBs 52 and 101, alpha-HCH, Beta-endosulfan and heptachlor epoxide could not be quantified; PCB 28, γ-HCH and p, p'-DDT were detected in 6.6, 0.9 and 8.05 % of subjects respectively and the Beta-HCH, HCB, p, p'-DDE, and PCBs 118, 138, 153 and 180 in the 73.8, 87.3, 98.6, 59.2, 97.6, 98.6 y 98.6 % respectively. After adjusting for age, there were no higher levels of BetaHCH in Barakaldo than in controls, (beta = 0.02, SE = 0.07), or HCB, p, p'DDE, PCB 118, PCB 138, PCB 153 and PCB 180. Conclusion: Six years after having solved the problem near to the factory and storage of HCH, there was no significantly higher levels of HCH, after adjustment for age(AU)

[Health impact evaluation of particle air pollution in five Spanish cities. European APHEIS project]. / Evaluación en cinco ciudades españolas del impacto en salud de la contaminación atmosférica por partículas. Proyecto europeo APHEIS.

BACKGROUND: The health effects of air pollution have been analyzed in numerous studies over recent years, thus having made it possible to quantify the relationship between the two. This study is aimed at analyzing the theoretical benefits which would be achieved by meeting the air quality objectives set forth under EC Directive 1999/30/EC with regard to suspended particles. METHODS: The exposure measurement was taken for Black Smoke (Barcelona, Bilbao, Valencia) and suspended particles under 10 microm (PM10) (Bilbao, Madrid y Sevilla). The health indicators calculated were the mortality due to all causes and respiratory and cardiovascular causes, and emergency hospital admissions and mortality due to respiratory and cardiovascular causes. In the case of PM10 the impact has been calculated because its effects to short-term, within a period of up to 40 days following exposure, and to long-term. For Black Smoke the effects only has been calculated to short-term. RESULTS: The daily levels of PM10 from exceeding 50 microg/m3 in Bilbao, Madrid and Sevilla cause the earlier death of 1.4/100,000 individuals per year because its effects. The effect within a period of up to 40 days following exposure is of 2.8 deaths/100,000. The total number of deaths per year which may be later due to long-term exposure if the yearly average is lowered to 20 microg/m3 is 68/100,000. CONCLUSIONS: The health impact of the current air pollution levels is quantifiable and is not insignificant. APHEIS and the impact evaluations may be of aid in healthcare planning and environmental policies.

Evaluación en cinco ciudades españolas del impacto en salud de la contaminación atmosférica por partículas. Proyecto europeo APHEIS / Health impact evaluation of particle air pollution in five spanish cities. European APHEIS project

Fundamento: Los efectos de la contaminación atmosféricasobre la salud han sido objeto en los últimos años de numerosos estudiosque han permitido cuantificar la asociación entre ambas El objetivode este trabajo es llevar a cabo la Evaluación del Impacto enSalud (EIS) calculando los beneficios que se obtendrían al cumplirlos objetivos establecidos por la Directiva 1999/30/CE en relacióncon las partículas en suspensión.Métodos: Se ha valorado el impacto en salud de la contaminación atmosférica por partículas en suspensión, para lo que se han utilizadodos indicadores distintos: Humos Negros (HN) (Barcelona,Bilbao, Valencia) y partículas en suspensión menores de 10 mm(PM10) (Bilbao, Madrid y Sevilla). Los indicadores de salud fueronla mortalidad por todas las causas, por causa respiratoria y por causacardiovascular, e ingresos hospitalarios urgentes por causa respiratoriay cardiovascular. El EIS se ha realizado mediante el cálculo de lafracción atribuible a la contaminación por partículas. En el caso dePM10 se ha calculado el impacto debido a efectos de la contaminación a corto plazo, los acumulados hasta 40 días después, y a largoplazo. Para HN únicamente se han calculado efectos a corto plazo.Resultados: Los niveles diarios de PM10 por encima de 50µg/m3 en Bilbao, Madrid y Sevilla son responsables de 1,4 muertesprematuras por 100.000 habitantes y año debido a sus efectos a cortoplazo y de 2,8 muertes/100.000 en un periodo de hasta 40 días trasla exposición. A largo plazo, el número de muertes prematuras atribuiblesa la contaminación media anual de PM10 por encima de 20µg/m3 es 68/100.000.Conclusiones: El impacto en salud de los niveles actuales decontaminación atmosférica es cuantificable y no despreciable.APHEIS y las evaluaciones de impacto pueden ayudar a la planificación sanitaria y a las políticas medioambientales

Background: The health effects of air pollution have beenanalyzed in numerous studies over recent years, thus having madeit possible to quantify the relationship between the two. This studyis aimed at analyzing the theoretical benefits which would be achievedby meeting the air quality objectives set forth under EC Directive1999/30/EC with regard to suspended particles.Methods: The exposure measurement was taken for Black Smoke(Barcelona, Bilbao, Valencia) and suspended particles under 10mm (PM10) (Bilbao, Madrid y Sevilla). The health indicators calculatedwere the mortality due to all causes and respiratory and cardiovascularcauses, and emergency hospital admissions and mortalitydue to respiratory and cardiovascular causes. In the case of PM10 theimpact has been calculated because its effects to short-term, within aperiod of up to 40 days following exposure, and to long-term. ForBlack Smoke the effects only has been calculated to short-term.Results: The daily levels of PM10 from exceeding 50 µg/m3 inBilbao, Madrid and Sevilla cause the earlier death of 1.4/100,000individuals per year because its effects. The effect within a period ofup to 40 days following exposure is of 2.8 deaths/100,000. The totalnumber of deaths per year which may be later due to long-term exposureif the yearly average is lowered to 20 µg/m3 is 68/100,000.Conclusions: The health impact of the current air pollutionlevels is quantifiable and is not insignificant. APHEIS and theimpact evaluations may be of aid in healthcare planning and environmentalpolicies