The efficacy of subcutaneous local analgesic infusion in the early postoperative period after bilateral total knee arthroplasty.

OBJECTIVES: This study aims to evaluate the analgesic and functional efficacy of subcutaneous local analgesic infusion (ScLAI) in the early postoperative period (especially on the second postoperative day) in patients undergoing simultaneous bilateral total knee arthroplasty with an intraoperative periarticular injection (PAI) of local analgesic cocktail. PATIENTS AND METHODS: Fifteen patients (1 male, 14 females; mean age 62 years; range 52 to 76 years) who underwent simultaneous bilateral total knee arthroplasty (30 knees) and who received the same pre- and intraoperative analgesic protocols were included in this randomized, double-blind, placebo-controlled study. By using a flexible catheter, bupivacaine was administered for ScLAI to either knee (ScLAI group) and placebo infusion was applied to the other one (control group). Postoperative visual analog scale (VAS) pain scores and knee functions were compared between bupivacain and placebo infused knees. RESULTS: In the ScLAI group, VAS pain scores were lower than the control group during knee flexion and straight leg raise activities (SLR) on the second postoperative day. ScLAI also prevented the rebound pain following intraoperative PAI of local analgesic cocktail and prolonged the analgesic efficacy period of the cocktail during both knee flexion and SLR. CONCLUSION: Subcutaneous infusion of bupivacaine in patients undergoing simultaneous bilateral total knee arthroplasty may prevent emergence of the rebound pain arising after application of intraoperative PAI of local analgesic cocktail and prolong the analgesic efficacy of the cocktail during both knee flexion and SLR activities on the second postoperative day.

Diagnostic efficacy of standard knee magnetic resonance imaging and radiography in evaluating integrity of anterior cruciate ligament before unicompartmental knee arthroplasty.

OBJECTIVE: The purpose of this study was to investigate the diagnostic efficacy of standard magnetic resonance imaging (MRI) and plain radiographs in determining the status of anterior cruciate ligament (ACL) for surgical decision-making processes in cases of medial unicompartmental knee arthroplasty (UKA). METHODS: A total of 59 knees of 36 consecutive patients who underwent knee replacement surgery were analyzed retrospectively. MRI scans were assessed independently by 3 observers (radiologists), while the plain radiographs were evaluated by an independent radiologist. Results were compared with the intraoperative ACL status. Cross tabulation was used for descriptive statistics to analyze sensitivity, specificity, and accuracy of MRI and plain radiographs. RESULTS: When the same observer assessed and classified the MRI twice, the reproducibility of the classification system varied from moderate to excellent. However, the interobserver concordance was moderate. The sensitivity of MRI was 73% and the specificity was 81%, while the sensitivity and specificity of plain radiographs was 36% and 79%, respectively. The accuracy of MRI was 80%, while that of the radiographs was 71%. CONCLUSION: Detection of intact ACL may be possible on available plain radiographs without necessity for additional means such as MRI, which may cause increase costs and loss of time. In cases where there is uncertainty regarding ACL integrity in degenerative knees, although standard MRI provides additional information on ACL status, it is not of sufficient diagnostic value.

Biomechanical evaluation of syndesmotic screw design via finite element analysis and Taguchi's method.

BACKGROUND: Screw fixation of syndesmotic injuries facilitates ligament healing and restoration of ankle stability, but failure of the screw might threaten the success of the treatment. Screw design parameters, such as outer diameter, inner diameter, thread pitch, leading edge radius, trailing edge radius, leading edge angle, and trailing edge angle, might have effects on the stresses that occur in the screws. This is the first study, to our knowledge, to investigate which geometric screw parameters play key roles in stresses that occur in screws used for syndesmotic fixation. METHODS: A three-dimensional finite element model of an ankle was reconstructed. Four different types of titanium screws­4.5-mm malleolar, 4-mm cancellous, 4-mm machine, and 3.5-mm cortical­were placed on this model. Physiologic load was applied to evaluate the stress in the screw. Then the contribution of each design factor to stress in the screws was analyzed systematically by Taguchi's robust design method. RESULTS: The maximum equivalent ductile failure (von Mises equivalent stress) value was found in the 4-mm cancellous screw (402 MPa). Taguchi's analysis showed that the descending order of contribution of the design factors to stress emerging on the screw is inner diameter, leading edge angle, thread pitch, outer diameter, and trailing edge angle. CONCLUSIONS: Stress that occurs in syndesmotic screws is closely related to their geometry and dimensions. According to the results, a 3.5-mm cortical screw with the ideal screw design regarding optimal parameters to resist against stresses in the syndesmosis seems more reasonable to choose in syndesmotic fixation.

Suture anchor fixation strength with or without augmentation in osteopenic and severely osteoporotic bones in rotator cuff repair: a biomechanical study on polyurethane foam model.

BACKGROUND: The purpose of the present study was to compare the results of various types of anchor applications with or without augmentation in both osteopenic and severely osteoporotic bone models. METHODS: Two different types of suture anchors were tested in severely osteoporotic (SOP) and osteopenic polyurethane (PU) foam blocks using an established protocol. An Instron machine applied static loading parallel to the axis of insertion until failure, and the mean anchor failure strengths were calculated. The mode of failure (anchor pullout, suture tear) was recorded. The anchors tested included the Corkscrew (CS) (Arthrex Inc., Naples, FL, USA) (without augmentation, polymethylmethacrylate (PMMA)-augmented, and bioabsorbable tricalcium phosphate (TCP) cement-augmented) and Corkscrew FT II (CS FT II) 5.5 mm (without augmentation as used routinely). RESULTS: The mean failure loads for both SOP and osteopenic PU foam blocks, respectively, were as follows: CS, 16.2 and 212.4 N; CS with TCP, 75.2 and 396 N; CS with PMMA, 101.2 and 528.8 N; CS FT II, 13.8 and 339.8 N. CONCLUSIONS: Augmentation of CS with TCP or PMMA would be essential to SOP bones. In the osteopenic bone model, although anchor fixation augmented with PMMA is the best fixation method, CS augmented with TCP cement or CS FT II without any need for augmentation may also be used as an alternative.

An assessment of sleep quality in patients undergoing total knee arthroplasty before and after surgery.

OBJECTIVE: The aim of this study was to compare the sleep quality of patients who underwent total knee arthroplasty before and after the surgery and analyze the effect of total knee arthroplasty on sleep quality. METHODS: The study included 42 patients (32 females, 10 males) who underwent total knee arthroplasty for primary knee osteoarthritis. For each patient the preoperative 1 day and postoperative 3 months results of Pittsburgh Sleep Quality Index (PSQI) and 100-mm visual analogue scale (VAS) were compared. RESULTS: The preoperative mean PSQI was 9. VAS score decreased in 97.6% of the patients, while sleep quality increased in 78.6%. 85.7% of the patients reported to have less episodes of pain related sleep disturbances. While both the PSQI and VAS improved after the surgery, there was no correlation between the parameters (p>0.05). CONCLUSION: Our results suggested that total knee arthroplasty surgery relieves pain and improves sleep quality. The improvement in sleep quality does not appear to be related to pain relief.

Femoral neck stress fracture in children: a case report, up-to-date review, and diagnostic algorithm.

Stress fracture of the femoral neck in skeletally immature individuals is a rare condition and generally seen as compressive type. Because the condition may lead to disastrous complications, femoral neck stress fracture must also be kept in mind in the differential diagnosis of pediatric hip pain. We present a case of compressive-type stress fracture of the femoral neck in a 10-year-old girl with left hip pain that was sustained for 4 weeks and emphasize the difficulty of early diagnosis with only a radiographic evaluation and put forward an algorithm for diagnosis and treatment.

Biomechanical evaluation of syndesmotic screw position: a finite-element analysis.

OBJECTIVES: To evaluate the stresses in syndesmotic screws and widening of syndesmosis under loading after placement of the screws at different levels from the ankle joint line and to determine the optimal level. METHODS: From a set of computed tomographic data of an ankle, a 3-dimensional finite-element model was reconstructed. Six fixation configurations of the syndesmosis with placement of 3.5 or 4.5 mm single tricortical screws at 20-45 mm from the tibiotalar joint were performed on this model. Physiological loads approximating those during both midstance and heel-off states of stance phase of normal walking were applied to evaluate the stress in the screw and widening of the syndesmosis. RESULTS: Among the 6 fixation configurations, the lowest von Mises stress was found in the screws placed 30-40 mm above the joint line (373.31-380.17 MPa for 3.5 mm cortical screw and 284.06-327.31 MPa for 4.5 mm cortical screw in midstance phases), whereas the least syndesmosis widening was determined when the screw was placed 30 mm above the tibial plafond (0.005 mm) for 3.5 mm cortical screw and 20, 25, and 30 mm above the tibial plafond (0.004 mm for each, respectively) for 4.5 mm cortical screw during midstance phases. CONCLUSIONS: This study showed that syndesmosis fixation at the level of 30-40 mm above the tibiotalar joint has advantages with regard to stress in screws in comparison with the other evaluated levels.

Three-dimensional finite element analysis used to compare six different methods of syndesmosis fixation with 3.5- or 4.5-mm titanium screws: a biomechanical study.

BACKGROUND: Use of thicker and longer (four cortices) screws or of multiple screws seems to be more stable and efficient for syndesmosis fixation. METHODS: A three-dimensional finite element model of an ankle was constructed from serial axial sections from an existing two-dimensional computed tomographic image. Constructions of syndesmosis fixation with 3.5-mm single tricortical, 3.5-mm single quadricortical, 3.5-mm double tricortical, 3.5-mm double quadricortical, 4.5-mm single tricortical, and 4.5-mm single quadricortical screws were performed on this model. Physiologic loads approximating those during stance phase normal walking were applied to this ankle system. Stress values on the screws using the six fixation methods were compared. RESULTS: The highest maximum stress was determined over 3.5-mm cortical screws applied as single quadricortical, and the lowest maximum stress was determined over the 4.5-mm cortical screw applied as single quadricortical. Stress on the 3.5-mm single screw with quadricortical application was found to be higher than that with tricortical application and also compared with the 4.5-mm quadricortical screw application. Differences between the 4.5-mm single tricortical and quadricortical screws and between the 3.5-mm single tricortical and 3.5-mm double tricortical screw applications were not significant. CONCLUSIONS: Quadricortical application of 3.5-mm single screws and tricortical application of 3.5-mm double cortical screws are not good choices for syndesmosis fixation. If the plan is tricortical application, a 3.5-mm single cortical screw is adequate. If quadricortical application of syndesmosis fixation is planned, a 4.5-mm cortical screw should be used.

Convex short segment instrumentation and hemi-chevron osteotomies for Putti type 1 thoracic hemivertebrae: a simple treatment option for patients under 5 years old.

STUDY DESIGN: A case series depicting the results of a novel surgical technique. OBJECTIVE: To prove that a minimally invasive surgical technique can effectively control and even correct congenital scoliosis caused by a fully segmented hemivertebra. SUMMARY OF BACKGROUND DATA: Congenital hemivertebrae have been treated by anterior and posterior growth arrest with/without fusion, anterior and posterior hemivertebrectomy, transpedicular hemivertebra excision, and transpedicular hemiepiphysiodesis. These approaches are complex and require experience. There is a need for a simple treatment method to treat these deformities. METHODS: Twelve patients under 5 years of age with Putti type1 hemivertebrae were treated by posterior convex short segment instrumentation, partial chevron osteotomies, and fusion. Scoliosis, segmental scoliosis, kyphosis, segmental kyphosis, trunk shift were measured both preoperatively and postoperatively. RESULTS: The mean correction of the segmental curve was 6 degrees (21%) which was maintained at the latest follow-up. The average final correction of the main curve was 23%. The trunk shift was 1.8 cm (range, 1-3 cm) preoperative and 1.4 cm (range, 0-2.5 cm) at the latest follow-up. The segmental angle of kyphosis averaged 11 degrees (range, -12 to 20 degrees) preoperative, and 14 degrees (range, 0-29 degrees) at the latest follow-up assessment. The values of the total thoracic kyphosis (T2-T12) were 29.5 degrees (range, 10-46 degrees) preoperative, 31 degrees (range, 10-44 degrees) postoperative, and 32 degrees (range, 16-45 degrees) at the last follow-up resulting in a mean improvement of 2 degrees. This improvement continued at the latest follow-up with a mean increase of 3 degrees. CONCLUSIONS: Transpedicular instrumentation is ideal for early correction in young children. The new posterior approach is much less invasive than the combined approaches or other posterior vertebrectomies and is well tolerated even in very young patients. The fusion segment is kept short. The deformities seem to stop progressing and this can avoid development of severe local deformities and secondary curves.

The comparison of the effects of intraoperative bleeding control and postoperative drain clamping methods on the postoperative blood loss and the need for transfusion following total knee arthroplasty.

OBJECTIVE: We aimed to determine and compare the effects of intraoperative bleeding control and two hours postoperative drain clamping method on postoperative wound drainage and the need for donor blood transfusion following total knee arthroplasty (TKA). METHODS: Seventy-one patients who underwent TKA were randomly assigned into two groups. Fourty-four knees of 32 patients comprised Group A and 51 knees of 39 patients comprised Group B. In Group A, no bleeding control was done and postoperatively, the drain was clamped for 2 hours. Then it was unclamped to begin aspiration after the 2nd hour. In Group B, the bleeding was controlled intraoperatively, and the drain was not clamped after the surgery. Drains were removed 48 hours after the surgery in both groups. Bilateral and unilateral arthroplasty patients were evaluated separately. The groups were compared for their preoperative and postoperative 3-day haemoglobin (Hb) levels, total drainage amount and total number of blood transfusions. RESULTS: The haemoglobin levels were similar in both groups preoperatively and at the 1st, 2nd and 3rd postoperative days. In Group A, the wound drainage was 696.1±235.4 ml in unilateral TKA patients and was 1010.8±535.5 ml in bilateral arthroplasty patients. In Group B, the wound drainage was 710.1±380.1 ml in unilateral TKA patients and was 878.3±489.6 ml in bilateral arthroplasty patients. The mean number of transfusions was 1.41 units with no significant differences between the groups. CONCLUSION: The two hour drain clamping method without intraoperative bleeding control does not seem to affect the amount of blood loss and the need for transfusion when compared to intraoperative bleeding control in total knee arthroplasty patients. Hovewer, it is a simple and feasible method and can be used to decrease the operation time.

[Healing of osteochondral defects in canine knee with avocado/soybean unsaponifiables: a morphometric comparative analysis]. / Avokado/soya fasülyesinin sabunlasmayan ekstresi verilen köpeklerin dizlerinde osteokondral defekt iyilesmesi: Bir karsilastirmali morfometrik analiz.

OBJECTIVES: This study aims to determine the effects of avocado/soybean unsaponifiables (ASU) on healing in a canine osteochondral defect model. MATERIALS AND METHODS: Fourteen dogs were included in the study and randomly divided into two groups. Two osteochondral defects were produced in the lateral aspect of the trochlear groove of the knee joint. The treatment group (group 1; n=7) was given 300 mg ASU capsules every three days whereas the control group (group 2; n=7) was given a normal diet. Animals were then allowed to ambulate normally until euthanasia at 15 weeks. The knees were dissected and the trochlear grooves with defects were removed for pathological examination. The amount of regenerated tissue was determined quantitatively using image analysis and the tissue content was evaluated semi-quantitatively using Safranin-O and Masson trichrome histochemical stains. Transforming growth factor beta (TGF-beta) increase was evaluated semi-quantitatively with immunohistochemical staining methods. RESULTS: Morphometric analysis revealed a significantly more immature repair tissue in group 1 (p<0.002). Both collagen and chondral tissue content of the regenerated tissue were significantly increased in group 1 (p<0.002). Compared to that in group 2, cartilage tissue in group 1 showed a much more marked immunostaining reaction of TGF-beta. CONCLUSION: Avocado/soybean unsaponifiables treatment stimulates the healing of the osteochondral defects in canine knee possibly by increasing TGF-beta in the tissues.

Easy retrieval of polyaxial tulip-head pedicle screws by "U" rod technique.

The number of fusion surgeries increase each year which also increase the need for implant removal. In some cases, it can be extremely hard to remove a pedicle screw especially when there is a mismatch of the screw and the screwdriver. Also the screwdrivers can be contaminated during the operation, and this will cause a delay till the instruments are re-sterilized. There is a need for the removal of screws without special instruments. We describe a method for removing tulip-head polyaxial pedicle screws without special instruments. The screws are removed using an Allen key, a rod bender and a "U" shaped rod. We successfully removed 76 screws in 11 recent cases without any complications. The "U" rod technique is a simple and useful technique for the removal of tulip-head polyaxial screws.

Bilateral post-injection fibrosis of the gluteal region mimicking lumbar disc herniation: a case report.

Tissue fibrosis is a known complication of intramuscular injections, which is especially seen in children due to vaccinations and injections. Herein we report a case of post injection gluteal fibrosis that had undergone two unsuccessful lumbar discectomies to treat the symptoms of this disease.A 45 years old male patient was consulted to our clinic from the department of neurochirurgy with complaints of bilateral hip pain. The patient was operated on for lumbar disc herniation in L4-5 level twice but his complaints had not resolved. A third operation including L4-5 instrumentation and fusion was planned. His examination revealed nodules in his both hips. His x-rays, MRI and blood tests were normal. He underwent bilateral gluteal fascia excision and his complaints resolved totally.The clinical diagnosis of post-injection fibrosis is problematic, due to the difficulty of determining the etiology. In many patients the diagnosis comes from a history of injection. Pain in the gluteal region is not a frequently described clinical feature of this condition. Many reports in the literature emphasize a contracture rather than pain.Post-injection fibrosis in the gluteal region may mimic lumbar disc herniation and a detailed physical examination is the key for correct differential diagnosis. In refractory cases not responding to conservative treatment, surgical excision of the nodules may lead to a complete clinical recovery of the patient.

Talonavicular joint approach to the talar body: a cadaver study.

BACKGROUND: Lesions of the talar dome or tumors within the talar body may require an open approach with medial or lateral malleolar osteotomies. The aim of this study was to evaluate the possibility and feasibility of a new minimally invasive approach without osteotomy, using the talonavicular joint (TJ) as the entry portal for lesions of the talar body. MATERIALS AND METHODS: Nine cadaveric feet were used for this study. Using the TJ and a 5-mm skin incision we aimed to reach the superolateral, superomedial, inferolateral and inferomedial corners of the talar body under fluoroscopy. A 2-mm Kirshner wire and a 4-mm cannulated drill bit were used to reach the desired target area and an angled curette was used for curettage after reaching the target. The proximity of vascular structures to the entry portal was noted. The talar and navicular joint surfaces were checked for any damage. The articular areas of the talar heads and the defect areas were measured. RESULTS: All 4 targets and even the posterior talus could be reached by this approach. The nearest neurovascular structures were the saphenous vein and the saphenous nerve. The navicular cartilage was not damaged in any specimen. The talar defect area corresponded to only 3.3% of the talar head cartilaginous area. CONCLUSION: The TJ approach can be used to reach lesions in all regions of the talar body without the need for an osteotomy. A mini-incision may be used to retract the saphenous nerve and vein. Damage to the talar head cartilage is minimal with this approach which requires no special equipments. CLINICAL RELEVANCE: This study shows that talar dome lesions can be reached with a minimally invasive method.

[The prevalence of low back pain and risk factors among adult population in Afyon region, Turkey]. / Afyonkarahisar ilinde eriskinlerde bel agrisi sikligi ve etkileyen faktörler.

OBJECTIVES: This study was designed to determine the prevalence of and risk factors for low back pain (LBP) in a sample of Turkish population among adults living in the Afyon region, Turkey. METHODS: A field screening investigation was performed in a total of 75 areas including the city center, 18 districts, and 57 associated small municipalities. Adequate sample size was determined as 1,990 and a total of 2,035 individuals (1,194 females, 841 males) were enrolled. Participants were inquired about age, occupation, sex, height, weight, history of LBP, hypertension, diabetes, and smoking. Depression symptoms were evaluated using the Symptom Checklist-90-Revised. RESULTS: The prevalence of lifetime LBP was 51%, and the prevalence of chronic LBP was 13.1%. Overall, 63.2% of women and 33.8% of men had LBP at least once in their lives (p=0.001). With regard to occupation, the highest incidence of LBP was seen in housewives (64.2%; p=0.0001), whose age and body mass index (BMI) were also higher compared to employed women. Depression (p=0.016) and increased BMI (p=0.000) were found to increase the risk for LBP, whereas smoking, hypertension, or diabetes were not correlated with the prevalence of LBP. Poverty was found to be the leading cause (39.7%) for not presenting to a physician. CONCLUSION: Among risk factors reported for LBP, many are also effective in Turkish population. Special attention should be given to the education of housewives in terms of low back protection, healthy nutrition, and family planning. Poverty seems to be a significant barrier to patient presentation to physicians, requiring extended social security coverage.