Development and validation of three brief versions of the humor styles questionnaire.

The Humor Styles Questionnaire (HSQ) is a frequently applied measure of individual differences in humor usage. However, previous research found several of its items to be unreliable and to provide insufficient information. Its 32-item length may also hinder its application in contexts in which short measures are required to maintain participant motivation, for instance large-scale assessments. In the present paper, we present three brief versions with five, four, and three items per subscale respectively, avoiding the questionable items. The results showed that the factor structure, internal consistency, and test-retest reliability of the original HSQ and the developed brief versions were as expected. Relations between the brief versions and psychological constructs (e.g., self-esteem, well-being, aggression, Big Five) were similar to the original HSQ. The findings support the psychometrical soundness and validity of three brief versions of the HSQ comparable to the original long version. General challenges in the assessment of humor are discussed.

Analyzing the Factor Structure of the Toronto Empathy Questionnaire: Dimensionality, Reliability, Validity, Measurement Invariance and One-Year Stability of the German Version.

In the face of heterogeneity in the measurement of empathy, the Toronto Empathy Questionnaire (TEQ; Spreng et al., Journal of Personality Assessment, 91(1), 62-71 (2009)) was developed as a brief unidimensional tool by statistically forming a consensus from existing measures of the construct. The present study aimed to (1) validate a German version of the TEQ, and (2) contribute empirical evidence to the ongoing debate regarding a singular versus multidimensional factor structure of the TEQ. One cross-sectional and two longitudinal studies were performed, with a total of 1,075 participants. Our initial exploratory factor analyses suggested either a one- or a two-factor structure (with the two-factors clustering straight and reverse-scored items); the two-factor model outperformed the one-factor model using confirmatory factor analyses. However, after negated items were replaced by positively reworded alternatives, both models fit the data equally well. A comparison of the correlation patterns with numerous external measures indicated that a second factor of the TEQ is a methodological artifact of item wording. Finally, a unidimensional TEQ scale showed sufficient internal consistency, two-week test-retest reliability, one-year stability, as well as convergent and discriminant validity with measures of empathy, emotion recognition, emotion regulation, altruism, social desirability, and the Big Five personality traits.

Cognitive dependencies and psychological health correlates of coherence in autobiographical reasoning.

Autobiographical reasoning is a process by which an individual creates a coherent life account. The degree of coherence in autobiographical reasoning has been related to psychological health correlates such as depression and self-esteem in previous studies, but with inconsistent findings. Similarly, the basic psychological processes required to achieve coherence have been previously studied with regard to intelligence, but infrequently, and also with mixed findings. In the present study, we first developed and evaluated a German version of the Awareness of Narrative Identity Questionnaire (ANIQ) as an established measure of self-reported coherence. Second, we tested for cognitive dependencies on intelligence and memory indices. Third, we analysed its associations with psychological health correlates. We assessed a sample of 272 participants and thereof 189 participants again two-weeks later. Results supported the assumptions of the German ANIQ's psychometric qualities (factor structure, test-retest reliability, invariance) and validity (with regard to self-consciousness, self-concept clarity, and written accounts of personal turning points). We found coherence to be independent of intelligence and verbal memory, but partially dependent on figural memory. Coherence was related to depression, positivity, self-esteem, and self-esteem stability, but not to anxiety, substantiating its salutogenic effects.

Testing the social mindfulness paradigm: Longitudinal evidence of its unidimensionality, reliability, validity, and replicability in a sample of health care providers.

OBJECTIVES: Social mindfulness is a relatively new concept in psychological research and is attracting increasing attention. Recent studies have provided evidence of its relevance with regard to prosocial behavior and empathy, but also concerning individual well-being and psychological health. In such studies, social mindfulness has been assessed using the social mindfulness paradigm by Van Doesum and colleagues, which is the standard measure of social mindfulness to date. However, evidence is scarce or lacking with regard to whether this measurement approach is unidimensional, whether it produces (test-retest) reliable and valid measurements, and whether its associations with personality and empathy are replicable. METHODS: To test these assumptions, we assessed a sample of 265 participants currently working in health care professions on social mindfulness, several concepts of empathy, and the HEXACO personality dimensions longitudinally at two measurement occasions. RESULTS: The results supported the assumption of unidimensionality of the measure. Partial support was found for its reliability, validity, and replicability. Test-retest reliability was acceptable, but the associations with personality and empathy turned out weaker than expected. CONCLUSIONS: The social mindfulness paradigm is an interesting approach toward understanding social mindfulness, meaning mindfulness of other people's needs. Potential directions for the further development of the social mindfulness paradigm and its network of relations, especially to empathy, are discussed.

The interplay of acceptance and effectiveness in intervention studies: the example of the empCARE training to reduce burnout and distress symptoms in health care providers.

OBJECTIVE: Although almost every study evaluating psychological interventions includes the two components of acceptability and effectivity, their relationship is rarely examined. The current study closes this gap by performing secondary analyses of the intervention program 'empCARE'. The goal was to analyze the relationship between these two evaluation components. DESIGN: The sample consists of 309 nurses (intervention group n = 172; control group n = 137). Data were collected before the training and longitudinally three times after the training. MAIN OUTCOME MEASURES: Psychological distress was assessed using the Symptom Checklist (SCL-90-R), and the Copenhagen Burnout Inventory. Personality traits were assessed using the HEXACO-60 and the Toronto Empathy Questionnaire. Acceptability was assessed using statements concerning participants' subjective evaluation of the training. RESULTS: The results show that the intervention program was effective. Acceptability, measured only in the intervention group, was quite high. However, no connection was found between effectivity and acceptability. On the contrary, the results show that acceptability assessments depend more on personality factors than on intervention success. CONCLUSIONS: Researchers should examine the relationship between acceptability and effectivity in their data. It does not seem appropriate to rely on acceptability measurements as the sole evaluation criterion capturing the success of an intervention.

The influence of emotional salience on gaze behavior in low and high trait empathy: an exploratory eye-tracking study.

Previous studies have shown that situational factors like emotional salience are associated with higher subjective levels of state empathy. The present eye-tracking study explored whether gaze behavior varies as a function of emotional salience between individuals with low and high self-reported trait empathy. In a between-subjects design, we presented three social scene images in the context of different emotion conditions (Scene 1: neutral versus positive; Scene 2: neutral versus negative; Scene 3: positive versus negative) and assessed the dwell times of individuals with low versus high self-reported empathy (measured with the Toronto Empathy Questionnaire; TEQ). Analyses revealed that whereas low- and high-TEQ participants differed in their gaze behavior after receiving neutral information, they did not differ after receiving positive or negative information. Our preliminary results suggest that gaze behavior may be more indicative of self-reported trait empathy in situations with low emotional salience than in situations with high emotional salience.

The risk of empathy: longitudinal associations between empathy and burnout.

OBJECTIVE: Prior research on the relation between empathy and burnout in social professions appears to be inconsistent. Whereas some studies have claimed that empathy functions as a buffer against burnout, others have argued that empathy contributes to the development of burnout. One explanation for this disparity may be methodological as most studies have relied on cross-sectional single-measure designs. To examine their cross-sectional and longitudinal associations, the present study analyzed cross-lagged data of several measures of empathy and burnout. DESIGN: Data from two longitudinal studies with three to twelve months between measurements were analyzed. The samples contained 172 nursing students and 186 nurses, respectively. MAIN OUTCOME MEASURES: Empathy was assessed using the Interpersonal Reactivity Index, the Toronto Empathy Questionnaire, the Geneva Emotion Recognition Test, and the Social Mindfulness Test Paradigm. Burnout was assessed using the Maslach Burnout Inventory, the Irritation Scale, and the Copenhagen Burnout Inventory. RESULTS: Results showed significant cross-sectional correlations between the questionnaire measures of empathy and burnout. However, there was insufficient support for the cross-lagged associations. CONCLUSIONS: Associations between empathy and burnout may be attributed to the methodological limitations of cross-sectional designs. However, the influence of potential moderators is discussed as a promising direction of future research.

A Comparison of the Predictive Validity of Self-Esteem Level and Directly Measured Self-Esteem Stability in the Temporal Prediction of Psychological Distress.

In contrast to the widely used assessment approach in which self-esteem stability is measured as the standard deviation of repeated measurements, direct measurements of self-esteem stability have hardly ever been implemented in longitudinal studies. The primary goal of the present study was to examine the temporal stability and predictive validity of a direct assessment of self-esteem stability compared with the trait level of self-esteem with respect to the prediction of psychological distress (PD). We examined a sample of 136 employees who completed self-report measures of both self-esteem level [Rosenberg Self-Esteem Scale (RSES)] and self-esteem stability [Self-Esteem Stability Scale (SESS)] along with a measure of PD (SCL-90) at two time points across an interval of 1 year. The results underline the relevance of perceived self-esteem stability in the temporal prediction of PD: After controlling for initial PD, we found that self-esteem stability predicted PD better than self-esteem level did. Therefore, we recommend that the RSES be expanded by adding the three SESS items that directly measure the stability of self-esteem.

Automated closed-system manufacturing of human monocyte-derived dendritic cells for cancer immunotherapy.

Dendritic cell (DC)-based vaccines have been successfully used for immunotherapy of cancer and infections. A major obstacle is the need for high-level class A cleanroom cGMP facilities for DC generation. The CliniMACS Prodigy® (Prodigy) represents a new platform integrating all GMP-compliant manufacturing steps in a closed system for automated production of various cellular products, notably T cells, NK cells and CD34+ cells. We now systematically tested its suitability for producing human mature monocyte-derived DCs (Mo-DCs), and optimized it by directly comparing the Prodigy approach to our established standard production of Mo-DCs from elutriated monocytes in dishes or bags. Upon step-by-step identification of an optimal cell concentration for the Prodigy's CentriCult culture chamber, the total yield (% of input CD14+ monocytes), phenotype, and functionality of mature Mo-DCs were equivalent to those generated by the standard protocol. Technician's labor time was comparable for both methods, but the Prodigy approach significantly reduced hands-on time and high-level clean room resources. In summary, using our optimized conditions for the CliniMACS Prodigy, human Mo-DCs for clinical application can be generated almost automatically in a fully closed system. A significant drawback of the Prodigy approach was, however, that due to the limited size of the CentriCult culture chamber, in contrast to our standard semi-closed elutriation approach, only one fourth of an apheresis could be processed at once.

The Self-esteem Stability Scale (SESS) for Cross-Sectional Direct Assessment of Self-esteem Stability.

Self-esteem stability describes fluctuations in the level of self-esteem experienced by individuals over a brief period of time. In recent decades, self-esteem stability has repeatedly been shown to be an important variable affecting psychological functioning. However, measures of self-esteem stability are few and lacking in validity. In this paper, we present the Self-Esteem Stability Scale (SESS), a unidimensional and very brief scale to directly assess self-esteem stability. In four studies (total N = 826), we describe the development of the SESS and present evidence for its validity with respect to individual outcomes (life satisfaction, neuroticism, and vulnerable narcissism) and dyadic outcomes (relationship satisfaction in self- and partner ratings) through direct comparisons with existing measures. The new SESS proved to be a stronger predictor than the existing scales and had incremental validity over and above self-esteem level. The results also showed that all cross-sectional measures of self-esteem stability were only moderately associated with variability in self-esteem levels assessed longitudinally with multiple administrations of the Rosenberg Self-Esteem Scale. We discuss this validity issue, arguing that direct and indirect assessment approaches measure relevant, yet different aspects of self-esteem stability.