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Int J Dev Neurosci ; 80(3): 189-196, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-32065434

RESUMO

OBJECTIVE: To characterize the spectrum of brain damages presented in children affected by Congenital Zika Syndrome (CZS), verify the existence of a co-occurrence pattern of these damages and discuss possible implications for the neuropsychological development. METHODS: Descriptive, quantitative, individualized, and cross-sectional study using secondary sources. We selected 136 children with CZS from the database of the Center of Strategic Information on Health Vigilance of the Municipal Office of Salvador, Brazil. We conducted descriptive and multiple correspondence analyses. RESULTS: Among the set of analyzed variables, microcephaly (51.5%), ventriculomegaly (57.4%), and brain calcifications (77.2%) were identified as the most frequent. The multiple correspondence analysis showed that the combination of these three variables (32.4%) was what better represented the spectrum of brain damages in the Central Nervous System. INTERPRETATION: Damage in the sensory-motor, cognitive and language development, as well as neurodevelopmental disorders, are described in the literature as impairments associated, either isolated or combined, with these damages, and it is worth highlighting that, in combined brain damages, impairments tend to be more severe. The findings of this study may contribute to understanding the repercussions of CZS on the neuropsychological development of children affected by the epidemic.


Assuntos
Encefalopatias/etiologia , Encéfalo/diagnóstico por imagem , Calcinose/etiologia , Desenvolvimento Infantil/fisiologia , Microcefalia/etiologia , Transtornos do Neurodesenvolvimento/etiologia , Infecção por Zika virus/complicações , Encefalopatias/diagnóstico por imagem , Brasil , Calcinose/diagnóstico por imagem , Estudos Transversais , Feminino , Humanos , Lactente , Masculino , Microcefalia/diagnóstico por imagem , Transtornos do Neurodesenvolvimento/diagnóstico por imagem , Neuroimagem
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