1.
J Org Chem
; 61(20): 7139-7146, 1996 Oct 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-11667617
RESUMO
The palladium-catalyzed desilylation-arylation of substituted vinylsilanes by p-iodoanisole in the presence of bidentate phosphine ligands is described. Apart from enhancing the rate of the reaction considerably, heteroatom-based functional groups in the vinylsilane moiety have a profound influence on the regiochemistry. A catalytic cycle for the chelation-controlled desilylation-arylation reaction involving five- and six-membered chelate rings is proposed.