Locally advanced hypopharyngeal squamous cell carcinoma: single-institution outcomes in a cohort of patients curatively treated either with or without larynx preservation.

OBJECTIVE: The present study was aimed at describing a single-institution experience in the curative treatment of patients diagnosed with locally advanced hypopharyngeal squamous cell carcinoma. MATERIALS AND METHODS: Data concerning all patients treated for locally advanced hypopharyngeal squamous cell carcinoma between January 2006 and June 2012 were reviewed. RESULTS: A total of 144 patients were included in the present study. The median follow-up period was 36.6 months. Median survival was 26 months, and 2-year and 5-year overall survival rates were, 51% and 30.5%, respectively. Median recurrence-free survival was 18 months and 2-year and 5-year recurrence-free survival rates were 42.8% and 28.5%, respectively. CONCLUSION: The outcomes in the present series are in line with the literature.

Locally advanced hypopharyngeal squamous cell carcinoma: single-institution outcomes in a cohort of patients curatively treated either with or without larynx preservation / Carcinoma espinocelular da hipofaringe: resultados de uma instituição numa coorte de doentes tratados com intenção curativa com ou sem preservação da laringe

Abstract Objective: The present study was aimed at describing a single-institution experience in the curative treatment of patients diagnosed with locally advanced hypopharyngeal squamous cell carcinoma. Materials and Methods: Data concerning all patients treated for locally advanced hypopharyngeal squamous cell carcinoma between January 2006 and June 2012 were reviewed. Results: A total of 144 patients were included in the present study. The median follow-up period was 36.6 months. Median survival was 26 months, and 2-year and 5-year overall survival rates were, 51% and 30.5%, respectively. Median recurrence-free survival was 18 months and 2-year and 5-year recurrence-free survival rates were 42.8% and 28.5%, respectively. Conclusion: The outcomes in the present series are in line with the literature.

Resumo Objetivo: O objetivo deste estudo é descrever a experiência de uma instituição no tratamento com intenção curativa de doentes diagnosticados com carcinoma espinocelular da hipofaringe localmente avançado. Materiais e Métodos: Os dados relativos aos doentes portadores de carcinoma espinocelular da hipofaringe localmente avançado tratados entre janeiro de 2006 e junho de 2012 foram revistos. Resultados: Foram incluídos 144 doentes. O tempo mediano de seguimento foi 36,6 meses. A sobrevivência mediana, aos 2 anos e aos 5 anos foi 26 meses, 51% e 30,5%, respectivamente. A sobrevivência livre de recorrência mediana, aos 2 anos e aos 5 anos foi 18 meses, 42,8% e 28,5%, respectivamente. Conclusão: Os resultados encontrados na nossa série estão em acordo com a literatura.