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1.
Sci Rep ; 14(1): 12211, 2024 05 28.
Artigo em Inglês | MEDLINE | ID: mdl-38806568

RESUMO

This paper deals with the mathematical analysis of Tuberculosis by using fractal fractional operator. Mycobacterium TB is the bacteria that causes tuberculosis. This airborne illness mostly impacts the lungs but may extend to other body organs. When the infected individual coughs, sneezes or speaks, the bacterium gets released into the air and travels from one person to another. Five classes have been formulated to study the dynamics of this disease: susceptible class, infected of DS, infected of MDR, isolated class, and recovered class. To study the suggested fractal fractional model's wellposedness associated with existence results, and boundedness of solutions. Further, the invariant region of the considered model, positive solutions, equilibrium point, and reproduction number. One would typically employ a fractional calculus approach to obtain numerical solutions for the fractional order Tuberculosis model using the Adams-Bashforth-Moulton method. The fractional order derivatives in the model can be approximated using appropriate numerical schemes designed for fractional order differential equations.


Assuntos
Fractais , Mycobacterium tuberculosis , Tuberculose , Humanos , Tuberculose/microbiologia , Mycobacterium tuberculosis/patogenicidade , Modelos Teóricos , Modelos Biológicos , Algoritmos
2.
Sci Rep ; 14(1): 12238, 2024 05 28.
Artigo em Inglês | MEDLINE | ID: mdl-38806539

RESUMO

This research conducts a detailed analysis of a nonlinear mathematical model representing COVID-19, incorporating both environmental factors and social distancing measures. It thoroughly analyzes the model's equilibrium points, computes the basic reproductive rate, and evaluates the stability of the model at disease-free and endemic equilibrium states, both locally and globally. Additionally, sensitivity analysis is carried out. The study develops a sophisticated stability theory, primarily focusing on the characteristics of the Volterra-Lyapunov (V-L) matrices method. To understand the dynamic behavior of COVID-19, numerical simulations are essential. For this purpose, the study employs a robust numerical technique known as the non-standard finite difference (NSFD) method, introduced by Mickens. Various results are visually presented through graphical representations across different parameter values to illustrate the impact of environmental factors and social distancing measures.


Assuntos
COVID-19 , Dinâmica não Linear , Distanciamento Físico , SARS-CoV-2 , COVID-19/epidemiologia , COVID-19/prevenção & controle , Humanos , SARS-CoV-2/isolamento & purificação , Modelos Teóricos , Meio Ambiente
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