Uterine smooth muscle tumor of uncertain malignant potential (STUMP) ABOUT a CASE.

INTRODUCTION AND IMPORTANCE: Uterine smooth muscle tumor of uncertain malignant potential (STUMP) is rare tumor, and regarded as sub-classification in uterine smooth muscle tumors between benign and malignant criteria. They represent a heterogeneous group of rare tumors. PRESENTATION OF CASE: We report a case of a STUMP tumor in a fifty-three-year-old patient who underwent surgery for a hysterectomy. DISCUSSION: STUMP often presents with nonspecific clinical manifestation the only confirmatory examination is anatomopathological and may be supported by immunohistochemistry, hysterectomy is currently considered the gold standard of treatment. CONCLUSION: Uterine STUMP tumor represents a therapeutic dilemma. A multidisciplinary approach is mandatory.

Occult primary breast cancer: Two cases report and literature review.

INTRODUCTION AND IMPORTANCE: Occult breast cancer (OBC) is defined as a clinically recognizable metastatic carcinoma arising from an undetectable primary breast tumor. PRESENTATION OF CASE: We report in this work 2 cases of occult breast cancer treated at the Mohammed VI center of onco-gynecology of the CHU of Casablanca. CLINICAL DISCUSSION: Significant advances in breast imaging have occurred since its description, decreasing its incidence. However current management is based upon old studies, with variable clinical, radiological and pathological definitions of OBC. CONCLUSION: The introduction of better diagnostic techniques and more detailed pathology continue to impact the true incidence of OBC. SUMMARY: Carcinoma of unknown primary is an intriguing clinical phenomenon that is defined as biopsy-proven metastasis of a malignant tumor in the absence of an identifiable primary site after a complete clinical workup. Carcinoma of unknown primary accounts for approximately 3 to 5% of all cancer diagnoses, and consists of a heterogeneous group of tumors that have acquired the ability to metastasize before the development of a clinically evident primary lesion. Clinical and radiological examinations represent the first steps in the diagnostic algorithm for Carcinoma of unknown primary syndrome. However, histological and immunohistochemical analyses, together with evaluation by a multidisciplinary team and adequate therapy are essential for the diagnosis and treatment of Carcinoma of unknown primary syndrome of OBC. We report in this work 2 cases of occult breast cancer treated at the Mohammed VI center of onco-gynecology of the CHU of Casablanca; A multidisciplinary approach including surgery, radiotherapy, hormonal and biological therapy was implemented. Currently, 10 month after the first presentation, the two patient received ipsilateral breast radiotherapy and sequential adjuvant chemotherapy followed by hormone therapy. Evolution was marked by good control.

Unilateral ovarian metastasis from renal clear cell carcinoma.

INTRODUCTION AND IMPORTANCE: Ovarian metastases of renal origin are rarely reported in the literature and pose a diagnostic problem because they are usually diagnosed at a distance from the primary cancer. PRESENTATION OF CASE: We report a case of unilateral ovarian metastasis from clear cell renal cell carcinoma fifteen years after nephrectomy in a fifty-six-year-old patient who underwent surgery for an abdominopelvic mass. CLINICAL DISCUSSION: The diagnosis of ovarian metastases can be made at the same time as the diagnosis of the primary cancer or at a distance from it, with an interval ranging from a few months to years later. In the case of our patient, the ovarian metastasis was diagnosed fifteen years after the nephrectomy. CONCLUSION: Ovarian metastases are exceptional secondary localizations of renal cancer, they can be unilateral or bilateral, and are usually discovered several years after the renal tumor.