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Indian J Pathol Microbiol ; 67(2): 411-414, 2024 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-38391382

RESUMO

ABSTRACT: Plasmablastic transformation of follicular lymphoma is very rare and has been reported in only 5 cases till date. We report a case of simultaneous identification of extranodal, soft tissue plasmablastic lymphoma in the ankle and bone marrow involvement by follicular lymphoma. This unusual case presentation is a challenge for the treating physician with the patient becoming resistant to chemotherapy and succumbing to the disease within a few months of diagnosis. These cases are known to have an aggressive clinical course with very poor prognosis and survival rate of less than 6 months. This report broadens the spectrum of morphological transformation of follicular lymphoma and it may represent a new category of high-grade transformation of follicular lymphoma.


Assuntos
Linfoma Folicular , Linfoma Plasmablástico , Humanos , Linfoma Folicular/patologia , Linfoma Folicular/diagnóstico , Linfoma Folicular/tratamento farmacológico , Linfoma Plasmablástico/patologia , Linfoma Plasmablástico/diagnóstico , Linfoma Plasmablástico/tratamento farmacológico , Medula Óssea/patologia , Masculino , Evolução Fatal , Pessoa de Meia-Idade , Imuno-Histoquímica , Transformação Celular Neoplásica/patologia
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