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1.
Anticancer Res ; 41(4): 2123-2132, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-33813423

RESUMO

BACKGROUND/AIM: Surgical stress has been correlated with higher rate of postoperative complications. Breast implants' surfaces (textured or smooth) represent an immunological stimulus. Our prospective study (BIAL2.20) evaluated post-operative leukocytes response at baseline and postoperative day (POD) 1 and 2 after implant-based breast reconstruction. PATIENTS AND METHODS: Between January and July 2020, 41 patients underwent reconstruction with textured (n=23) or smooth (n=18) implants. A full blood count and lymphocyte subsets were collected before surgery, on POD1 and POD2. Data were evaluated as difference and relative difference from baseline by two-way analysis of variance test (2-way-ANOVA). Mann-Whitney U-test was performed at each POD, whenever between-group 2-way-ANOVA reached statistical significance. RESULTS: Within-group-analysis showed statistically significant total leukocytosis in both groups. Within-group-analysis of lymphocytes subsets demonstrated statistically significant lymphopenia in the textured group for T-lymphocytes, and T-helper cells. Between-group-analysis showed statistically significant lymphopenia in T-helper subsets in the textured group at POD1 and POD2, when compared with the smooth group. CONCLUSION: Textured implants demonstrated a statistically significant impairment of T-helper trend during POD1 and POD2 when compared to smooth implants by between-group 2-way-ANOVA.


Assuntos
Implante Mamário , Implantes de Mama/efeitos adversos , Linfopenia/etiologia , Mamoplastia , Complicações Pós-Operatórias/imunologia , Linfócitos T Auxiliares-Indutores/patologia , Adulto , Idoso , Implante Mamário/efeitos adversos , Implante Mamário/instrumentação , Implante Mamário/métodos , Neoplasias da Mama/patologia , Neoplasias da Mama/cirurgia , Desenho de Equipamento/efeitos adversos , Feminino , Humanos , Linfopenia/diagnóstico , Linfopenia/imunologia , Mamoplastia/efeitos adversos , Mamoplastia/instrumentação , Mamoplastia/métodos , Mastectomia/métodos , Pessoa de Meia-Idade , Complicações Pós-Operatórias/diagnóstico , Complicações Pós-Operatórias/patologia , Período Pós-Operatório , Estudos Prospectivos , Fatores de Tempo
2.
Artigo em Inglês | WPRIM (Pacífico Ocidental) | ID: wpr-830760

RESUMO

This article portrays the authors’ clinical experience of a complex case of lower extremity reconstruction using a recycled pedicle from 10 years old free latissimus dorsi musculocutaneous flap to supply a new free anterolateral thigh flap for proximal tibia wound defect reconstruction. It provides clinical evidence that muscle neovascularization occurs and supports the dogma peripheral tissue neovascularization. This case stipulates that recycling of pedicle is feasible, when used with appropriate strategy and safety and also provides evidence for the long-term survival of greater saphenous vein grafts in lower extremity reconstruction.

3.
Artigo em Inglês | WPRIM (Pacífico Ocidental) | ID: wpr-762815

RESUMO

Mobile computing devices (MCDs), such as smartphones and tablets, are revolutionizing medical practice. These devices are almost universally available and offer a multitude of capabilities, including online features, streaming capabilities, high-quality cameras, and numerous applications. Within the surgical field, MCDs are increasingly being used for simulations. Microsurgery is an expanding field of surgery that presents unique challenges to both trainees and trainers. Simulation-based training and assessment in microsurgery currently play an integral role in the preparation of trainee surgeons in a safe and informative environment. MCDs address these challenges in a novel way by providing valuable adjuncts to microsurgical training, assessment, and clinical practice through low-cost, effective, and widely accessible solutions. Herein, we present a review of the capabilities, accessibility, and relevance of MCDs for technical skills acquisition, training, and clinical microsurgery practice, and consider the possibility of their wider use in the future of microsurgical training and education.


Assuntos
Educação , Educação Médica Continuada , Microcirurgia , Rios , Smartphone , Cirurgiões , Comprimidos
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