Correlation of human papillomavirus 16 and 18 with cervical cancer and their diagnosis methods in Iranian women: A systematic review and meta-analysis.

BACKGROUND: Human papillomavirus (HPV) is a sexually transmitted virus and related to the development of cervical cancer (CC). To determine the association between high-risk HPV types and CC, we undertook a systematic review and meta-analysis of recently reported prevalence of HPV16 and 18 in Iranian women identified with cervical infections. MATERIALS AND METHODS: Prevalence studies were identified between 2002 and 2018 using several databases including Medline, Web of Science, Embase, Google Scholar, Iranmedex, and Scientific Information Database. RESULTS: For patients with CC, 57% (95% confidence interval [95% CI] = 43.7%-70.4%) were HPV positive, 48.5% (95% CI = 31.8%-65.2%) were HPV16 and 12.5% (95% CI = 8.8%-16.2%) were HPV18 positive. CONCLUSION: The results from meta-analysis indicate a relatively high prevalence of high-risk HPV among women infected with CC.

Early detection of cervical cancer based on high-risk HPV DNA-based genosensors: A systematic review.

Human papillomavirus type (HPV) is a common cause of sexually transmitted disease (STD) in humans. HPV types 16 and 18 as the highest risk types are related with gynecologic malignancy and cervical cancer (CC) among women worldwide. Recently, considerable development of genosensors, which allows dynamic monitoring of hybridization events for HPV-16 and 18, has been a topic of focus by many researchers. In this systematic review, we highlight the route of development of DNA-based genosensory detection methods for diagnosis of high risk of HPV precancer. Biosensor detection methods of HPV-16 and 18 was investigated from 1994 to 2018 using several databases including PubMed, Cochrane Library, Scopus, Google Scholar, SID, and Scientific Information Database. Manual search of references of retrieved articles were also performed. A total of 50 studies were reviewed. By analyzing the most recent developed electrochemical biosensors for the identification of HPV, we observed that the sensor platform fabricated by Wang et al. holds the lowest detection limit reported in the literature for the DNA of HPV-16. Up to this date, optical, electrochemical, and piezoelectric systems are the main transducers used in the development of biosensors. Among the most sensitive techniques available to study the biorecognition activity of the sensors, we highlight the biosensors based fluorescent, EIS, and QCM. The current systematic review focuses on the sensory diagnostic methods that are being used to detect HPV-16 and 18 worldwide. Special emphasis is given on the sensory techniques that can diagnosis the individuals with CC. © 2018 BioFactors, 45(2):101-117, 2019.

All-optical wireless wavelength multiplexing and demultiplexing using resonant cavity.

The potential capability of wireless wavelength multiplexing and demultiplexing can enable the next development of smaller photonic counterparts for network architectures. This paper numerically represents a new design of a wireless transmission in C-band infrared wavelengths within two identical resonant cavities between photonic chips. This system consists of an H1 rod-type two-dimensional photonic crystal (PhC) microcavity, which can be operated as both a transmitter and a receiver without interfering with the signal in each PhC waveguide. By using the point-to-point oscillatory light-field exchange between resonant cavities, two independent photonic circuits are linked with each other. The obtained results show that the multi-resonance wavelengths in one chip can be transferred to another chip located far away by ten times the highest resonance wavelength. Such a device can be useful for integrated optical circuit interconnect and small-scale sensors between photonic chips.