Survival rate of patients with bladder cancer and its related factors in Kurdistan Province (2013-2018): a population-based study.

BACKGROUND: Bladder cancer is one of the most common urinary tract cancers. This study aims to estimate the survival rate of patients with bladder cancer according to the Cox proportional hazards model based on some key relevant variables. METHODS: In this retrospective population-based cohort study that explores the survival of patients with bladder cancer and its related factors, we first collected demographic information and medical records of 321 patients with bladder cancer through in-person and telephone interviews. Then, in the analysis phase, Kaplan-Meier method and log-rank test were used to draw the survival curve, compare the groups, and explore the effect of risk factors on the patient survival rate using Cox proportional hazards model. RESULTS: The median survival rate of patients was 63.2 (54.7-72) months and one, three and five-year survival rates were 87%, 68% and 54%, respectively. The results of multiple analyses using Cox's proportional hazards model revealed that variables of sex (male gender) (HR = 11.8, 95% CI: 0.4-100.7), more than 65 year of age (HR = 4.1, 95% CI: 0.4-11), occupation, income level, (HR = 0.4, 95% CI: 0.2-0.8), well differentiated tumor grade (HR = 3.2, 95% CI: 1.7-6) and disease stage influenced the survival rate of patients (p < 0.05). CONCLUSION: The survival rate of patients with bladder cancer in Kurdistan province is relatively low. Given the impact of the disease stage on the survival rate, adequate access to appropriate diagnostic and treatment services as well as planning for screening and early diagnosis, especially in men, can increase the survival rate of patients.

The association between insomnia and cardiovascular risk factors in bus drivers in Iran.

BACKGROUND: Road accidents are one of the most important issues in Iran which more than eighteen thousand persons are died annually because of this problem. Among the major reasons for this issue, sleepiness and cardiovascular disorder can be mentioned. OBJECTIVE: To investigate the association between insomnia and cardiovascular risk factors among professional drivers who are at high risk during driving. METHODS: A total of 1232 male bus drivers were included in the study and two different kinds of data sets were collected: (1) Sleep disorder information using Athens Insomnia Scale (AIS) and (2) Cardiovascular parameters such as systematic measurement of blood pressure, electrocardiography (ECG), total cholesterol, and triglyceride. RESULTS: Our study demonstrated that the prevalence of insomnia in professional bus drivers was 8 percent. The study showed significant association between age, diastolic hypertension and work experience with final awakening earlier than desired (P < 0.05), the rate of the triglyceride level and total sleep duration (p = 0.02), and BMI and sleepiness during the day (P < 0.05). CONCLUSIONS: Our study suggested that elevated serum triglyceride levels and increased diastolic blood pressure may be associated with some sleep complaints in drivers.