[The effect of disorders of thrombocyte functional activity on the microcirculatory status in the lungs and on external respiratory function in patients with aspirin-induced asthma]. / Vliianie narushenii funktsional'noi aktivnosti trombotsitov na sostoianie mikrotsirkuliatsii v legkikh i funktsiiu vneshnego dykhaniia u bol'nykh aspirinovoi astmoi.

Platelet aggregation, pulmonary microcirculation and external respiration were studied against clinical appearance of the disease in 20 patients with aspirin-sensitive asthma (ASA) and 10 asthmatics without aspirin intolerance. All ASA patients were found to exhibit higher intensity and rate of platelet aggregation induced by ATP and heparin. Capillary pulmonary circulation in them was decreased 2-fold compared to nonaspirin asthma patients. All ASA cases had obstructive impairment of pulmonary ventilation in peripheral bronchi. The more serious were defects in platelet function, the more significant were microcirculatory and external respiratory alterations in ASA. Thus, it is evident that changes in platelet function play an important role in the genesis of pulmonary microcirculation and external respiration affections in ASA patients.

[Radiodiagnosis in the evaluation of lung dysfunction in bronchial asthma]. / Luchevaia diagnostika v otsenke disfunktsii lëgkikh pri pronkhialnoi astme.

A combined method of x-ray and radiologic examinations of the lungs revealed in asthmatics general disorders of the ventilation and perfusion with fine functional changes, presenting as local areas of asthmatic hyperinflation, anatomically involving separate segments or lobes of the lungs. Capillary circulation disorders develop here as well. Local swelling sites are characterized by a certain mobility: they may disappear and reappear in different lung segments. The functional potentialities of the diaphragm are virtually always reduced.