Assuntos
Neoplasias de Cabeça e Pescoço/diagnóstico , Neoplasias de Cabeça e Pescoço/secundário , Melanoma/diagnóstico , Melanoma/secundário , Complicações Neoplásicas na Gravidez/diagnóstico , Couro Cabeludo , Neoplasias Cutâneas/diagnóstico , Adolescente , Diagnóstico Tardio , Feminino , Neoplasias de Cabeça e Pescoço/patologia , Doença de Hodgkin/diagnóstico , Humanos , Melanoma/patologia , Gravidez , Complicações Neoplásicas na Gravidez/patologia , Couro Cabeludo/patologia , Neoplasias Cutâneas/patologia , Ultrassonografia Pré-NatalRESUMO
Studies have shown that triggering receptor expressed on myeloid cells-1 (TREM-1) is the mediator and activator of neutrophils and monocytes after stimulation with lipopolysaccharide (LPS), heat-inactivated Gram (-) bacteria, Gram (+) bacteria or fungi. Different studies have measured the expression of TREM-1 in patients with bacterial infections and critical states. The purpose of this study was to evaluate the expression of TREM-1 in circulating maternal leukocytes in premature rupture of the membranes (PRM). Two groups of patients were included in this case control study: pregnant women with PRM and healthy controls. All patients were free of any infection, including cervix and urinary tract. Although all patients expressed TREM-1 to some extent, there was no statistically significant difference in the expression of different cellularities in both groups; except for the mononuclear leukocytes (p < 0.05). In this study, TREM-1 was not altered in PRM.
