Assuntos
Dermatite Alérgica de Contato/etiologia , Irritantes/efeitos adversos , Borracha/efeitos adversos , Hipoclorito de Sódio/química , Ziram/análogos & derivados , Tornozelo , Vestuário , Dermatite Alérgica de Contato/patologia , Feminino , Humanos , Irritantes/química , Pessoa de Meia-Idade , Testes do Emplastro , Borracha/química , Hipoclorito de Sódio/efeitos adversos , Ziram/químicaRESUMO
Se informan 12 casos de leucodermia en bajadores dedicados a la sintesis de paraterbutilfenol. Se estudian macroscopicamente y ultramicroscopicamente las lesiones dermicas y se investigan, en detalle, las posibles repercusiones generales. Se comparan con hallazgos similares en otros paises y se proponen algunas hipotesis sobre el mecanismo patogenico para basar las medidas terapeuticas y profilacticas idoneas
Assuntos
Humanos , Vitiligo , Doenças Profissionais , Fenóis , MelaninasRESUMO
La dermatitis de contacto alergica por colorantes en calcetines, constituye un problema cronico e incapacitante, su diagnostico no siempre es sencillo y a menudo se confunde con otras dermatosis que afectan los pies.Los agentes etiologicos principales son los colorantes azoicos derivados del aminoazobenceno y otros colorantes de tipo antraquinonico que pueden jugar tambien un papel importante. El diagnostico preciso puede efectuarse unicamente por medio de pruebas epicutaneas con los colorantes utilizados en la tincion de acetato, nylon y poliester, asi como con fragmentos de las prendas sospechosas, lo cual permite identificarlas, facilitando las alternativas adecuadas para el uso de calcetines que pueden ser tolerados por el paciente. Es importante completar el estudio inmunologico con otras substancias que pueden originar dermatitis de contacto en los pies como son materiales del calzado y medicamentos topicos
Assuntos
Dermatite de Contato , Coloração e RotulagemRESUMO
Hyper-pigmentation as a manifestation of contact sensitivity to optical brighteners has previously been reported. In 1973 we observed an epidemic of pigmented contact dermatitis occurring in a textile mill in connection with the manufacture of drill fabrics impregnated with a recently introduced azo dye coupling component Naphthol AS. Of the 53 workers included in the study, 12 presented a spotted pattern of hyperpigmentation mainly affecting the exposed areas, but without pruritus, 18 were pigmented to a lesser degree, and in 21 it was not possible to discern any well-defined discoloration; some of the patients in the last group, however, complained of slight pruritus. The last two patients who were fair-skinned showed a reddish-brown pigmentation and a well pronounced pruritus. Hyper-pigmentation was most pronounced in individuals with dark complexions, whereas fair-skinned patient also showed "classical" eczematous symptoms including pruritus. A field study demonstrated direct exposure to the chemical. All 53 patients were patch-tested with Naphthol AS 5% in water, and 24 were found to be positive. Histological features were melanocyte proliferation, incontinence of pigment, and various degrees of damage to the basal layer.
Assuntos
Anilidas/efeitos adversos , Dermatite de Contato/etiologia , Dermatite Ocupacional/induzido quimicamente , Naftóis/efeitos adversos , Transtornos da Pigmentação/induzido quimicamente , Dermatite Ocupacional/diagnóstico , Dermatite Ocupacional/patologia , Humanos , Testes do Emplastro , Transtornos da Pigmentação/diagnóstico , Transtornos da Pigmentação/patologiaRESUMO
Occupational koilonychia of the finger-nails among cabinet makers is reported. Six cases occurred in workers in close contact with a mixture of organic solvents (thinners). The deformity involved particularly the thumb, index and middle finger-nails, due to a particular way of cleaning metal accessories in finished furniture. The possible mechanism is discussed.