RESUMO
Angiotensin-converting enzyme inhibitors (ACEI) are one of the most frequently used drugs in the therapy of cardiovascular diseases. Beneficial therapeutic effects may be accompanied by different adverse reactions including angioedema. Recently published data suggest that ACEI-induced angioedema can be life-threatening without emergent intervention, for example due to the respiratory arrest. Monitoring this adverse Jreaction may be especially important for elderly patients who probably receive many different medicines and supplements and thus might be particularly at risk of adverse drug reactions. In the paper we describe two cases of ACEI-induced angioedema in older patients.
Assuntos
Inibidores da Enzima Conversora de Angiotensina/efeitos adversos , Anti-Hipertensivos/efeitos adversos , Edema/induzido quimicamente , Lábio/efeitos dos fármacos , Perindopril/efeitos adversos , Idoso , Substituição de Medicamentos , Edema/diagnóstico , Edema/tratamento farmacológico , Feminino , Humanos , Lábio/patologia , Masculino , Pessoa de Meia-Idade , Resultado do TratamentoRESUMO
The article prescribes short review of adverse effects of glucocorticoids on the basis of clinical case of exacerbation of iatrogenic adrenal failure in the course of acute coronary syndrome with ST elevation (ACS STEMI) in a patient with chronic obstructive pulmonary disease (COPD).