RESUMO
It was found that alcohol caused pathological and irreversible decrements of the redox-state potential (redosis) in the pancreas and the liver. On giving reducing agents, a compensatory oxidosis developed, and this could prevent the cell damaging effect of alcohol. This effect was most marked in the reversible phase, while it could be effective also in the irreversible phase. By measuring the redox buffer capacity in the tissues it is possible to determine the measure of reversibility of the injury caused by alcohol.
Assuntos
Etanol/toxicidade , Fígado/efeitos dos fármacos , Pâncreas/efeitos dos fármacos , Animais , Cisteína/farmacologia , Feminino , Fígado/ultraestrutura , Masculino , Microscopia Eletrônica , Oxirredução/efeitos dos fármacos , Pâncreas/ultraestrutura , Ratos , Tiamina/farmacologia , Ácido Tióctico/farmacologia , Vitamina E/farmacologiaRESUMO
Ninety-eight (39.6%) out of 247 Listeria monocytogenes strains isolated from a variety of sources were typable by 27 phases. Of the 31 human strains only 3 belonged to phage types occurring in cattle, sheep and surface waters. A close correlation existed between serotype and phage type of the strains. Serotype 1/2 and 4 strains isolated in Hungary were less frequently typable than cultures originating from France. Phage typing is a useful tool for epidemiological tracing but, for a more effective differentiation, the number of phages should be increased and the method should be standardized.
