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1.
Rev Sci Instrum ; 87(1): 015115, 2016 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-26827361

RESUMO

A comparative study of electrical breakdown properties of deionized water (H2O) and heavy water (D2O) is presented with two different electrode materials (stainless steel (SS) and brass) and polarity (positive and negative) combinations. The pulsed (∼a few tens of nanoseconds) discharges are conducted by applying high voltage (∼a few hundred kV) pulse between two hemisphere electrodes of the same material, spaced 3 mm apart, at room temperature (∼26-28 °C) with the help of Tesla based pulse generator. It is observed that breakdown occurred in heavy water at lesser voltage and in short duration compared to deionized water irrespective of the electrode material and applied voltage polarity chosen. SS electrodes are seen to perform better in terms of the voltage withstanding capacity of the liquid dielectric as compared to brass electrodes. Further, discharges with negative polarity are found to give slightly enhanced discharge breakdown voltage when compared with those with positive polarity. The observations corroborate well with conductivity measurements carried out on original and post-treated liquid samples. An interpretation of the observations is attempted using Fourier transform infrared measurements on original and post-treated liquids as well as in situ emission spectra studies. A yet another important observation from the emission spectra has been that even short (nanosecond) duration discharges result in the formation of a considerable amount of ions injected into the liquid from the electrodes in a similar manner as reported for long (microseconds) discharges. The experimental observations show that deionised water is better suited for high voltage applications and also offer a comparison of the discharge behaviour with different electrodes and polarities.

2.
Rev Sci Instrum ; 85(6): 063503, 2014 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-24985815

RESUMO

A Guillemin type E pulse forming network (PFN) has been designed, developed, and tested for its application in generating high density (~1 × 10(18) m(-3)) plasmas. In the present study, plasma thus generated is utilized to investigate the interaction of high power microwaves (HPMs) with plasma in an experimental architecture known as SYMPLE (System for Microwave PLasma Experiment). Plasma discharges of ~100 µs (max) duration are to be produced, by delivering energy of 5 kJ stored in a PFN to the plasma source, a washer gun. The output of the PFN, in terms of its rise time, flat top and amplitude, needs to be tailored, depending on the experimental requirements. An ignitron (NL8900) trigger generator (ITG) is developed in-house to control the PFN discharge through the gun. This ITG is also to be used in a circuit that synchronizes the HPM and plasma shots, to ensure that HPM-plasma interaction takes place during a temporal regime where appropriate parametric conditions are satisfied. Hence it is necessary to retain the jitter within ±2.5 µs. Further, requirement on plasma quiescence (~10%) necessitates maintaining the ripple within 5%. The developmental work of the PFN, keeping in view the above criteria and the test results, is presented in this paper. The parameters of the PFN have been analytically approximated and verified with PSPICE simulation. The test results presented include rise time ~5-8 µs, flat top variable in the range 20-100 µs, ripple within ~1.5%, and jitter within ±2.5 µs, producing quiescent (<10%) plasma discharge meeting the experimental requirements.

3.
Indian J Crit Care Med ; 17(2): 82-6, 2013 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-23983412

RESUMO

AIMS: Aggressive therapy aimed at desired end-points of Early Goal Directed Therapy (EGDT) is the cornerstone of septic shock management. A key endpoint that improves outcomes is achieving central venous saturation (ScvO2) >70%. The gold standard to measure ScvO2 is by a co-oximeter (co-ox). SETTINGS AND DESIGN: This prospective, observational study from a multidisciplinary pediatric intensive care unit (PICU) was conducted to assess the validity of ScvO2 levels by standard ABG (stand ABG) machine in comparison with co-ox in conditions that shifted the oxygen dissociation curve (ODC) to the right or left in sick children and controls. MATERIALS AND METHODS: Data from paired samples was tested for correlation coefficient for pH, paCO2, paO2, and ScvO2. Tests for correlation (Pearson's coefficient) and agreement (Bland-Altman analysis) were performed on ScvO2 values obtained in various subgroups. Sensitivity and specificity for ScvO2 values determined by standard ABG machine versus co-ox were calculated in reference to EGDT endpoints. RESULTS: A total of 141 paired samples were collected from 82 children. Despite a statistically significant difference in the pH and ScvO2, there was good linear correlation between these parameters. Limits of agreement between ScvO2 measured by standard ABG machine and co-ox by Bland-Altman gave 2.3% bias with 95% CI of -24.2% to 19.5%. Sensitivity and specificity of standard ABG machine in detecting low ScvO2 in shock was 84.21% and 93.18% respectively, while it was false positive in 4 samples. CONCLUSIONS: The less expensive standard ABG machine showed satisfactory correlation with gold standard co-ox over a range of patient conditions; however, the wide range for agreement was of concern and it performed particularly poorly in anemic patients.

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