1.
J Biol Regul Homeost Agents
; 33(2): 457-460, 2019.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30916512
RESUMO
Keratoconus (KC) is a multifactorial, progressive, degenerative corneal disorder with an incidence of approximately 1 in 2,000 subjects.
Assuntos
Ceratocone/enzimologia , Superóxido Dismutase-1/metabolismo , Fatores de Transcrição/metabolismo , Humanos , Ceratocone/genética , Superóxido Dismutase-1/genética , Fatores de Transcrição/genética
2.
J Biol Regul Homeost Agents
; 33(6): 1879-1884, 2019.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31970969
3.
J Biol Regul Homeost Agents
; 32(6): 1515-1518, 2018.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30574758
RESUMO
Keratoconus (KC) is a complex, genetically heterogeneous, multifactorial degenerative corneal disorder, with incidence of approximately 1 per 2000 of the population. KC follows an autosomal recessive or dominant pattern of inheritance and is, apparently, associated with genes which interact with environmental, genetic and/or other factors. The present report focuses on the VSX1 gene, for which there is general agreement that it is involved in KC and other corneal pathologies, and critically details the evidence for its involvement in KC.
