RESUMO
BACKGROUND: Phenolformaldehyde resins, especially the para-tertiary-butylphenolformaldehyde resin (PTBP-FR), are widely used in industry and in numerous materials of everyday use, such as glues, adhesives, or inks. They can cause many occupational and nonoccupational cases of dermatitis. PATIENTS AND METHODS: Forty-one patients with positive patch test results to PTBP-FR were selected for this study. They were patch-tested with a series of chemically related compounds and cross-reactions were noted. RESULTS: Phenolformaldehyde resin (PF-R) was frequently positive (65.8%), whereas other compounds gave a much smaller number of positive results. Cases of occupational exposure (24.4%), location of the dermatitis (hands were involved in 46.3% of cases), and possible sources of exposure (shoes were the responsible agent in 12.2% of cases) were evaluated. CONCLUSIONS: Phenolformaldehyde resins are an important cause of contact dermatitis and must be studied chemically and clinically to improve the prognosis of sensitized patients.
Assuntos
Alérgenos/imunologia , Dermatite Alérgica de Contato , Resinas Sintéticas/efeitos adversos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Reações Cruzadas/imunologia , Dermatite Alérgica de Contato/diagnóstico , Dermatite Alérgica de Contato/imunologia , Dermatite Ocupacional/diagnóstico , Dermatite Ocupacional/imunologia , Feminino , Seguimentos , Formaldeído/efeitos adversos , Humanos , Hipersensibilidade/imunologia , Masculino , Pessoa de Meia-Idade , Testes do EmplastroAssuntos
Dermatite Alérgica de Contato/etiologia , Hipersensibilidade a Drogas/etiologia , Dermatoses Faciais/diagnóstico , Resorcinóis/efeitos adversos , Idoso , Blefarite/tratamento farmacológico , Dermatite Alérgica de Contato/diagnóstico , Hipersensibilidade a Drogas/diagnóstico , Pálpebras , Feminino , Humanos , Pomadas/efeitos adversos , Testes do EmplastroRESUMO
In 1988, 633 patients attending our Allergology Center underwent patch testing with the standard series recommended by the Gruppo Italiano Ricerca Dermatiti da Contatto e Ambientali. Of these, 576 patients completed the test correctly and their results were evaluated statistically. Nickel, cobalt, and potassium dichromate were the three most common sensitizers; concomitant positive reactions were present at significant levels. The authors discuss environmental and occupational exposure to contact allergens and correlate the major sites of dermatitis with the sensitivity to each metal in patients of both sexes.
Assuntos
Cobalto/efeitos adversos , Dermatite de Contato/etiologia , Níquel/efeitos adversos , Testes do Emplastro , Dicromato de Potássio/efeitos adversos , Dermatite de Contato/diagnóstico , Feminino , Humanos , MasculinoRESUMO
In January 1989, the Center for Sexually Transmitted Diseases (STD) of Galliera Hospital-Genoa was equipped with a network of 5 Personal Computers connected by a Token Ring to another Personal Computer which is the "server" unit. The Authors report their experiences in the use of the computer system and examine the advantages of networking in the management of a Center for Sexually Transmitted Disease.
Assuntos
Hospitais Especializados , Microcomputadores , Infecções Sexualmente Transmissíveis , ItáliaRESUMO
Thirty-nine HIV-negative men, without apparent genital warts, were evaluated for evidence of subclinical genital condylomata by visual examination of the genitalia with colposcopy after the application of 5% acetic acid. 24 patients (group I) had a history of recurrent genital condylomata; 8 (group II) were sexual partners of women with HPV-related lesions and 7 (group III) presented another sexually transmitted disease. Under colposcopic magnification, acetowhite areas were biopsied for conventional histology and in situ hybridization using 6/11, 16/18 and 31/35/51 HPV-DNA probes. Colposcopy and histologic features were positive for condylomata acuminata in 16 patients of group III (14%). HPV 16/18 - whose oncogenic potentiality is well known - was detected in 3 patients: of these, one patient of group I presented a histologic picture suggestive of bowenoid papulosis.
Assuntos
Colposcopia , Condiloma Acuminado/diagnóstico , Neoplasias dos Genitais Masculinos/diagnóstico , Adolescente , Adulto , Condiloma Acuminado/patologia , Sondas de DNA de HPV , Diagnóstico Diferencial , Neoplasias dos Genitais Masculinos/patologia , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
The causes of death of 50 patients who had had lichen planus have been investigated and compared with those of 50 patients with psoriasis and with those of the general population. Patients with lichen planus were as old as those with psoriasis and in the general population at the time of death, but the diseases causing death differed. Malignant tumors, particularly those of the gut and the bladder, and malignant hemopathies exceeded the expected prevalence. In addition, autoimmune diseases were more common than in patients with psoriasis and in the general population. Multiple sclerosis and primitive pulmonary fibrosis have never been described before in patients with lichen planus.
