[Clinical and electroencephalographic characteristics of specific language impairment in children and an evaluation of the efficacy of cerebrolysin].

UNLABELLED: To study different forms of specific language impairment in children and to evaluate the efficacy of cerebrolysin in clinical and electroencephalographic aspects. MATERIAL AND METHODS: Authors examined 60 children, aged 5-7 years, with a specific language impairment (SLI). RESULTS AND CONCLUSION: The study showed the significantly higher severity of speech disorders, a higher degree of asthenia and dyspraxia/dysgnosia in a group of children with a disorder of receptive language (SLI-R) compared to children with a disorder of expressive speech (SLI-E). A comparative analysis of the EEG power spectra showed large values of slow theta-band EEG in children with SLI compared with healthy children. Children with SLI-R were characterized by the increase in theta rhythm power in the occipital region compared with children with SLI-E. The high efficacy of cerebrolysin in the treatment of this disease (an improvement was obtained in 73.3% of cases) was demonstrated, with the best effect in children with SLI-E (80.0% of cases).

[A role of neuroprotective therapy in the rehabilitation of children with sensorineural hearing loss, IV degrees, after cochlear implanta-tion]. / Rol' neiroprotektivnoi terapii v abilitatsii detei s sensonevral'noi tugoukhost'yu IV stepeni posle provedeniya kokhlearnoi implantatsii.

OBJECTIVE: To study clinical/psychological characteristics in children with sensorineural hearing loss, IV degrees, before and after the cochlear implantation (CI) and to assess the dynamics of speech development during the rehabilitation using the neuroprotective drug cerebrolysin. MATERIAL AND METHODS: Authors examined 93 patients, aged from 5 to 8 years. The main group (n=46) received cerebrolysin, the control group was not treated with this drug. A diagnostic study included patient's history, neurological and neuropsychological examinations, auditory perception and sound reproduction. RESULTS AND CONCLUSION: According to the Meaningful Use of Speech Scale, 23% of children of the main group demonstrated the best results due to the better speech communication strategies. No significant between-group differences were found in the level of auditory perception 6 months after CI. The level of articulation was higher in the main group. Cognitive functioning was improved in children treated with cerebrolysin.