Assuntos
Maus-Tratos Infantis/diagnóstico , Hematoma Subdural/diagnóstico por imagem , Fratura do Crânio com Afundamento/diagnóstico por imagem , Derrame Subdural/diagnóstico por imagem , Autopsia/métodos , Diagnóstico Diferencial , Evolução Fatal , Feminino , Humanos , Lactente , Radiografia , Fratura do Crânio com Afundamento/etiologia , Derrame Subdural/etiologiaRESUMO
Death from hypoxic cerebral damage 1 week after manual strangulation is described, with a discussion of the competing pathophysiological mechanisms responsible for the fatal outcome in this case, and in manual strangulation in general.
Assuntos
Hipóxia Encefálica/etiologia , Lesões do Pescoço , Adulto , Evolução Fatal , Feminino , Humanos , Hipóxia Encefálica/complicações , Pescoço/patologia , Fatores de TempoRESUMO
Seventy-six cases of primary thyroid lymphoma have been reviewed employing the Kiel classification. These lymphomas are almost entirely of follicle centre cell origin, occur predominantly in elderly females, and are frequently associated with lymphocytic thyroiditis or Hashimoto's disease. The overall prognosis is variable, with long-term survival in a substantial number of cases following thyroidectomy and radiotherapy. Results of histological examination including immunoperoxidase studies are described. It is proposed that thyroid lymphoma represents a neoplasm of mucosa-associated lymphoid tissue (MALT), and the implications of this are discussed.
Assuntos
Tecido Linfoide/patologia , Linfoma Folicular/patologia , Linfoma/patologia , Glândula Tireoide/patologia , Neoplasias da Glândula Tireoide/patologia , Adulto , Idoso , Feminino , Seguimentos , Humanos , Técnicas Imunoenzimáticas , Linfoma/mortalidade , Linfoma Folicular/mortalidade , Masculino , Pessoa de Meia-Idade , Mucosa/patologia , Plasmócitos/patologia , Neoplasias da Glândula Tireoide/mortalidade , Fatores de TempoRESUMO
The role of the secretory immunoglobulin system in urinary tract neoplasia has been investigated by staining formalin-fixed, paraffin-wax embedded sections of normal and abnormal urinary tract epithelium for secretory component (SC), IgA and J (joining) chain. Normal mucosa contains IgA with J chain and SC as a thin superficial layer on surface umbrella cells and in small amounts in the cytoplasm of intermediate cells. Inflamed mucosa is infiltrated by many IgA and J chain positive plasma cells in the lamina propria and there is IgA, SC and J chain in the cytoplasm of the second layer of the epithelium as much as in surface umbrella cells. Epithelium with moderate to severe dysplasia and invasive transitional cell carcinoma is almost always negative, containing only occasional cells with cytoplasmic IgA, J chain and SC, whilst surface staining is entirely absent.
