[Relationship of the value of excess body weight to the blood concentration of cholesterol and triglycerides and the level of the basic hormones regulating lipid metabolism in healthy men 30 to 50 years old]. / Vzaimosviaz' velichiny izbytochnoi massy tela s kontsentratsiei kholesterina, triglitseridov krovi i urovnem osnovnykh gormonov, reguliruiushchikh lipidnyi obmen u zdorovykh muzhchin 30--50 let.

The basal levels of cholesterol (CS), triglycerides (TG), sugar, immunoreactive insulin (IRI), cortisol, testosterone, triiodothyronine (T3) and thyroxine (T4) were compared in 116 healthy males with risk factors of developing coronary heart disease (CHD), aged 45, engaged in administrative activities associated with stress and hypokinesia, with relation to normo-, hyperlipoproteinemia (NLP and HLP) and percentage of excessive body mass (IBM). In NLP as well as in HLP with an increase in IBM a tendency to elevated levels of CS, TG, sugar, IRI was noted, however there was no direct parallelism. In both cases the IBM value within the limits of obesity, I degree, did not influence the concentration of blood cortisol and testosterone. T3 and T4 levels were significantly decreased in males with IBM exceeding the normal one by 25%. They demonstrated the highest content of blood CS, TG and sugar on an empty stomach.

[Role of excessive body weight and hormonal changes in the development of the main types of hyperlipoproteinemia]. / RoL' izbytochnoi masy tela i gormonal'nykh sdvigov v razvitii osnovnykh tipov giperlipoproteidemii.

Hyperlipoproteinemia (HLP) was detected in 67.3% of 118 males without CHD (with the mean age of 44.7 years) engaged in intellectual occupations. The excessive body weight in this group was twice higher, and blood insulin 1.5 times higher, while the STH levels twice lower as compared to patients with normolipoproteinemia (NLP). The mean concentrations of ACTH, cortisol, T3, T4 in both groups were equal and did not exceed normal. In males with the II A type of HLP versus those with the II B and IV types, the excessive body weight and blood cortisol content were 1.5 times as low but testosterone levels were 1.5 times as high and approached those in individuals with NLP.