[Water-electrolyte balance in patients with cerebral arachnoiditis]. / Osobennosti vodno-élektrolitnogo obmena u bol'nykh tserebral'nym arakhnoiditom.

The paper discusses the results of studying the water-electrolyte exchange in patients with cerebral arachnoiditis. Basically new evidence has been obtained for the mechanisms of interaction of the liquor-circulating and osmoregulating systems of the body. There is a more intensive excretion of sodium and H2O during load sodium and water tests and a decrease in antidiuretic effects on hyperosmotic exposures in patients than in healthy individuals. It is suggested that these changes are compensatory and caused by the lowered sensitivity of neurons in the supraoptic and paraventricular nuclei, the decreased secretion of vasopressin and the functional rearrangement of mechanisms responsible for natriuretic regulation.