Toward a memory perspective on eating psychopathology: An investigation of the types of childhood and adolescence memories that are associated with eating disorder symptoms.

The cognitive mechanisms through which specific life events affect the development and maintenance of eating disorders (ED) have received limited attention in the scientific literature. The present research aims to address this gap by adopting a memory perspective to explore the type of life events associated with eating psychopathology and how these events are encoded and reconstructed as memories. Two studies (n = 208 and n = 193) were conducted to investigate the relationship between specific memories and eating disorder psychopathology. Study 1 focused on parent-related memories, while Study 2 examined childhood/adolescence memories. Results from both studies revealed that need thwarting and shame in memories were associated with eating disorder symptoms, but only when individuals drew symbolic connections between these memories and food or eating behavior. Moreover, need thwarting and shame in such memories were associated with other eating and body image outcomes, including uncontrolled eating and body esteem. These results also held after controlling for a host of known predictors of eating disorder psychopathology, such as BMI, perfectionism, or thin ideal internalization. Overall, the present findings suggest that the reprocessing of memories symbolically and idiosyncratically linked to food and eating behavior might be a fruitful clinical intervention.

Reflux After Sleeve Gastrectomy: Safety and Effectiveness of Laparoscopic Ligamentum Teres Cardiopexy, a Single-Center Experience.

BACKGROUND: Obesity is a well-known risk factor for gastroesophageal reflux disease (GERD). Even though symptoms may be mitigated or resolved with the weight loss caused by sleeve gastrectomy (SG), it may be associated with higher incidences of postoperative GERD. Ligamentum teres cardiopexy (LTC) is an alternative to Roux-en-Y gastric bypass, the gold standard treatment for GERD. METHODS: This study was a retrospective single-center chart review, all patients in this cohort underwent LTC to treat refractory GERD at our institution. The option for LTC was presented after patients' refusal to undergo RYGB conversion. We collected baseline characteristics, standard demographics, pre-operative tests and imaging, and SG information, as well as intraoperative and perioperative data regarding LTC, and postoperative complications. RESULTS: Our cohort included 29 patients; most were Caucasian (44.8%) females (86.2%). The mean weight and BMI before LTC were 216.5 ± 39.3 lb and 36.1 ± 5.4 kg/m2, respectively. Mean total body-weight loss (TBWL) at 12 and 24 months were 28.7% ± 9.5% and 28.4% ± 12.4%, respectively. The mean interval between the index bariatric surgery and LTC was 59.9 ± 34.9 months, mean operative time was 67 ± 18.2 min, and median length of stay (LOS) was 1 day (IQR = 1-2 days). Twelve patients (57.1%) were able to discontinue antisecretory medications, while 9 (42.9%) still required them to remain asymptomatic. Mortality and reoperation rates were 0% and the incidence of complication was 19.4% (n = 6). CONCLUSIONS: LTC is a safe and effective surgical alternative to treat refractory GERD symptoms after SG.

Terapia Ocupacional com crianças e jovens em pandemia: análise de processos de trabalho e reflexões para uma prática emancipatória / Occupational Therapy with children and young people during pandemic: analysis of work processes and reflections for an emancipatory practice / Terapia Ocupacional con niños y jóvenes en pandemia: análisis de procesos de trabajo y reflexiones para una práctica emancipativa

Contextualização: A partir de práticas de terapeutas ocupacionais na cidade de São Paulo, durante a pandemia do coronavírus, este artigo apresenta dois processos de trabalhos de terapeutas ocupacionais com crianças e jovens. Síntese dos elementos do estudo: análise dos processos de trabalho das profissionais no âmbito do SUS. Ferramentas específicas fundadas emuma abordagem crítica foram identificadas e descritas: análise do cotidiano com desenvolvimento de recursos adaptativos; análise de elementos da reprodução social; mapeamento, análise, proposição e legitimação de atividades significativas; articulação de recursos materiais para engajamento nestas atividades. Conclusão: Enfatizaram-se as contradições do modo de produção capitalista e das estruturas sociais ao produzir reflexões sobre uma prática situada e contextualizada.(AU) Palavras-chave: Terapia Ocupacional. COVID-19. Infância. Juventude. Saúde Coletiva

Contextualization: Based on the practices of occupational therapists in the city of São Paulo, during the coronavirus pandemic, this article presented two work processes of occupational therapists with children and young people. Synthesis of the study's elements: analysis of the processes of professionals in the work within the scope of SUS. Specific tools based on a critical approach were identified and described: daily analysis and the development of adaptive resources; analysis of elements of social reproduction; mapping, analysis, proposition and legitimization of meaningful activities; articulation of material resources to engage in these activities. Conclusion: The contradictions of the mode of production and social structures were emphasized while producing reflections on a situated and contextualized practice.(AU) Keywords: Occupational Therapy. COVID-19. Childhood youth. Collective Health

Objetivo: A partir de las prácticas de los terapeutas ocupacionales en la ciudad de São Paulo, durante la pandemia del coronavirus, este artículo presentado dos procesos de trabajo de terapeutas ocupacionales con niños y jóvenes. Síntesis de los elementos del estudio: análisis de los procesos de trabajo de los profesionales, en el ámbito del SUS. Se identificaron y describieron herramientas específicas basadas en un enfoque crítico: análisis diario con el desarrollo de recursos adaptativos; análisis de elementos de reproducción social; mapeo, análisis, propuesta y legitimación de actividades significativas; articulación de recursos materiales para participación en estas actividades. ConclusiónLas contradicciones del modo de producción y las estructuras sociales se enfatizaron al producir reflexiones sobre una práctica situada y contextualizada.(AU) Palabras clave: Niñez. Colaboración intersectorial. Terapia ocupacional. Participación comunitaria

A saúde mental dos adolescentes brasileiros: pesquisa nacional de saúde do escolar de 2019 / La salud mental de los adolescentes brasileños: encuesta nacional de salud escolar 2019 / Brazilian adolescents' mental health: 2019 national school health survey

RESUMO Objetivo: descrever as prevalências dos indicadores de saúde mental entre os escolares brasileiros. Método: estudo transversal com dados da Pesquisa Nacional de Saúde do Escolar (PeNSE) de 2019. Estimou-se as prevalências e intervalos de confiança de 95% (IC95%) dos indicadores de saúde mental dos adolescentes brasileiros de 13 a 17 anos, segundo idade, sexo, dependência administrativa da escola e Unidade da Federação. Resultados: dos 125.123 escolares de 13 a 17 anos investigados, 4,0% (IC95% 3,7-4,3) mencionaram que não tinham amigos próximos; 50,6% (IC95% 49,8-51,4) sentiram-se preocupados com as coisas comuns do dia a dia; 31,4% sentiram-se tristes na maioria das vezes ou sempre; 30,0% (IC95% 29,4 - 30,6) achavam que ninguém se preocupava com eles; 40,9% (IC95% 40,2 - 41,5) ficaram irritados, nervosos ou mal-humorados; 21,4% (IC95% 20,9-22,0) sentiam que a vida não vale a pena ser vivida; e 17,7% (IC95% 17,2-18,2) apresentaram autoavaliação em saúde mental negativa. A maioria desses indicadores foram mais frequentes em escolares de 16 e 17 anos, no sexo feminino e em escolas públicas. Conclusão: evidenciou-se o aumento do sofrimento mental entre os adolescentes brasileiros pelos indicadores de saúde mental da PeNSE edição 2019. Os resultados revelaram relações de desigualdades estruturais de gênero e classe social. É necessário maior investimento em políticas públicas a fim de diminuir as consequências do sofrimento mental entre os adolescentes brasileiros.

RESUMEN Objetivo: describir la prevalencia de los indicadores de salud mental entre los escolares brasileños. Método: estudio transversal con datos de la Encuesta Nacional de Salud Escolar 2019 (PeNSE). Se estimó la prevalencia y los intervalos de confianza del 95% (IC95%) de los indicadores de salud mental de los adolescentes brasileños de 13 a 17 años, según la edad, el género, la dependencia administrativa de la escuela y la Unidad de la Federación. Resultados: de los 125. 123 escolares de 13 a 17 años investigados, el 4,0% (IC95%: 3,7-4,3) mencionaron que no tenían amigos íntimos; el 50,6% (IC95%: 49,8-51,4) se sentían preocupados por las cosas comunes de la vida diaria; el 31,4% se sentían tristes la mayor parte del tiempo o siempre; el 30,0% (IC95% 29,4 - 30,6) sentía que nadie se preocupaba por ellos; el 40,9% (IC95% 40,2 - 41,5) estaba irritable, nervioso o de mal humor; el 21,4% (IC95% 20,9 - 22,0) sentía que no valía la pena vivir; y el 17,7% (IC95% 17,2 - 18,2) tenía una autoevaluación negativa de su salud mental. La mayoría de estos indicadores eran más frecuentes en los escolares de 16 y 17 años, en las mujeres y en los colegios públicos. Conclusión: se evidenció un aumento de la angustia mental entre los adolescentes brasileños a través de los indicadores de salud mental de la edición PeNSE 2019. Los resultados revelan relaciones de desigualdades estructurales de género y clase social. Es necesario invertir más en políticas públicas para reducir las consecuencias del malestar mental entre los adolescentes brasileños.

ABSTRACT Objective: to describe the prevalence values of the mental health indicators among in-school Brazilian adolescents. Method: a cross-sectional and descriptive study conducted with data from the 2019 National School Health Survey (Pesquisa Nacional de Saúde do Escolar, PeNSE). The prevalence and 95% confidence intervals (95% CI) of the mental health indicators of Brazilian adolescents aged from 13 to 17 years old were estimated according to age, gender, school's administrative system and Federation Unit. Results: of the 125,123 students aged from 13 to 17 years old that were investigated, 4.0% (95% CI: 3.7-4.3) mentioned that they did not have close friends; 50.6% (95% CI: 49.8-51.4) felt worried about common everyday issues; 31.4% felt sad most of the times or always; 30.0% (95% CI: 29.4-30.6) thought that no one cared about them; 40.9% (95% CI: 40.2-41.5) were irritated, nervous or in a bad mood; 21.4% (95% CI: 20.9-22.0) felt that life was not worth living; and 17.7% (95% CI: 17.2-18.2) presented negative mental health self-assessments. Most of these indicators were more frequent in female adolescents aged 16 and 17 years attending public schools. Conclusion: an increase in mental distress was identified among Brazilian adolescents according to the mental health indicators of PeNSE 2019. The results revealed relationships marked by gender and social class structural inequalities. More investment is necessary in public policies in order to reduce the consequences of mental distress among Brazilian adolescents.

Loneliness and associated factors among Brazilian adolescents: results of national adolescent school-based health survey 2015

Abstract Objective: To identify the associated factors to loneliness among Brazilian adolescents, considering this is a knowledge gap and given its severity. The United Nations estimates that mental health problems affect approximately 20% of adolescents worldwide. Methods: This is a cross-sectional study with data from the National Adolescent School-based Health Survey 2015, conducted with students aged 13-17 in Brazil. The statistical analysis was performed with the calculation of the prevalence of feeling loneliness reported. Poisson regression with the adjusted Prevalence Ratio was used to evaluate the association between sociodemographic characteristics, family context, mental health and lifestyles, and feelings of loneliness. Results: 15,5% of Brazilian students reported loneliness in the last 12 months. Female gender, higher maternal education, insomnia and be bullying victims rarely or sometimes and most of the time or always had a higher prevalence rate of loneliness. Having friends, having a meal with parents or guardians 5 days or more a week and having understanding parents showed a lower prevalence ratio for loneliness. Conclusion: Loneliness feeling is frequent among adolescents and is associated with female gender, less social and family support, intra-family violence and risk behaviors such as alcohol consumption and bullying. Policies to promote physical and mental well-being in this age group, stimulating friendship and family participation in the lives of adolescents should be made.

Loneliness and associated factors among Brazilian adolescents: results of national adolescent school-based health survey 2015.

OBJECTIVE: To identify the associated factors to loneliness among Brazilian adolescents, considering this is a knowledge gap and given its severity. The United Nations estimates that mental health problems affect approximately 20% of adolescents worldwide. METHODS: This is a cross-sectional study with data from the National Adolescent School-based Health Survey 2015, conducted with students aged 13-17 in Brazil. The statistical analysis was performed with the calculation of the prevalence of feeling loneliness reported. Poisson regression with the adjusted Prevalence Ratio was used to evaluate the association between sociodemographic characteristics, family context, mental health and lifestyles, and feelings of loneliness. RESULTS: 15,5% of Brazilian students reported loneliness in the last 12 months. Female gender, higher maternal education, insomnia and be bullying victims rarely or sometimes and most of the time or always had a higher prevalence rate of loneliness. Having friends, having a meal with parents or guardians 5 days or more a week and having understanding parents showed a lower prevalence ratio for loneliness. CONCLUSION: Loneliness feeling is frequent among adolescents and is associated with female gender, less social and family support, intra-family violence and risk behaviors such as alcohol consumption and bullying. Policies to promote physical and mental well-being in this age group, stimulating friendship and family participation in the lives of adolescents should be made .

Risk and protective factors related to domestic violence against Brazilian adolescents. / Fatores de risco e proteção relacionados à violência intrafamiliar contra os adolescentes brasileiros.

OBJECTIVE: To describe the factors associated with domestic violence against Brazilian adolescents. METHODOLOGY: Descriptive analysis of the variables and calculation of the prevalence of intrafamily violence reported by the students was performed, followed by multinomial regression with calculation of the adjusted odds ratio to analyze the association between the variables and the outcome investigated. RESULTS: Black skin color (ORa = 1.9; 95%CI 1.4 - 2.7) and brown (ORa = 1.4; 95%CI 1.0 - 1.9), insomnia (ORa = 1.8; 95%CI 1.4 - 2.4), bullying (ORa = 2.5; 95%CI 1.7 - 3.7) and alcohol consumption (ORa = 1.5; 95%CI 1.1 - 1.9) increased the chances of adolescents suffering an episode of intrafamily violence. Bullying (ORa = 3.9; 95%CI 2.8 - 5.3) and alcohol consumption (ORa = 2.2; 95%CI 1.7 - 2.7) contributed up to 4 times more not to suffer more than one episode of domestic violence. Habits such as eating with family (ORa = 0.7; 95%CI 0.5 - 1.0) and having parents who understand their problems (ORa = 0.6; 95%CI 0.5 - 0,7) proved to be protective factors for intrafamily violence. CONCLUSION: Intrafamily violence against adolescents is related to family interactions, psychoactive substance use and violence in the school environment. Thus, it reveals the importance of the participation of parents and guardians in the prevention of violence and risk behaviors in the lives of Brazilian adolescents.

Fatores de risco e proteção relacionados à violência intrafamiliar contra os adolescentes brasileiros / Risk and protective factors related to domestic violence against Brazilian adolescents

RESUMO: Objetivo: Descrever os fatores associados à violência intrafamiliar contra os adolescentes brasileiros. Métodos: Realizaram-se a análise descritiva das variáveis e o cálculo da prevalência da violência intrafamiliar relatada pelos estudantes, seguidos da regressão multinominal com cálculo da razão de chances ajustada para análise da associação entre as variáveis e o desfecho investigado. Resultados: A cor de pele preta (ORa = 1,9; IC95% 1,4 - 2,7) e parda (ORa = 1,4; IC95% 1,0 - 1,9), a insônia (ORa = 1,8; IC95% 1,4 - 2,4), o bullying (ORa = 2,5; IC95% 1,7 - 3,7) e o consumo de bebida alcoólica (ORa = 1,5; IC95% 1,1 - 1,9) aumentaram as chances dos adolescentes sofrerem um episódio de violência intrafamiliar. O bullying (ORa = 3,9; IC95% 2,8 - 5,3) e o consumo de bebida alcoólica (ORa = 2,2; IC95% 1,7 - 2,7) contribuíram com até quatro vezes mais no sofrer em mais de um episódio de violência intrafamiliar. Hábitos como fazer refeição com a família (ORa = 0,7; IC95% 0,5 - 1,0) e ter pais que entendem seus problemas (ORa = 0,6; IC95% 0,5 - 0,7) mostraram-se como fatores protetores para a violência intrafamiliar. Conclusão: A violência intrafamiliar contra o adolescente está relacionada às interações familiares, uso de substâncias psicoativas e à violência no ambiente escolar. Assim, revela a importância da participação de pais e responsáveis na prevenção da violência e dos comportamentos de risco na vida dos adolescentes brasileiros.

ABSTRACT: Objective: To describe the factors associated with domestic violence against Brazilian adolescents. Methodology: Descriptive analysis of the variables and calculation of the prevalence of intrafamily violence reported by the students was performed, followed by multinomial regression with calculation of the adjusted odds ratio to analyze the association between the variables and the outcome investigated. Results: Black skin color (ORa = 1.9; 95%CI 1.4 - 2.7) and brown (ORa = 1.4; 95%CI 1.0 - 1.9), insomnia (ORa = 1.8; 95%CI 1.4 - 2.4), bullying (ORa = 2.5; 95%CI 1.7 - 3.7) and alcohol consumption (ORa = 1.5; 95%CI 1.1 - 1.9) increased the chances of adolescents suffering an episode of intrafamily violence. Bullying (ORa = 3.9; 95%CI 2.8 - 5.3) and alcohol consumption (ORa = 2.2; 95%CI 1.7 - 2.7) contributed up to 4 times more not to suffer more than one episode of domestic violence. Habits such as eating with family (ORa = 0.7; 95%CI 0.5 - 1.0) and having parents who understand their problems (ORa = 0.6; 95%CI 0.5 - 0,7) proved to be protective factors for intrafamily violence. Conclusion: Intrafamily violence against adolescents is related to family interactions, psychoactive substance use and violence in the school environment. Thus, it reveals the importance of the participation of parents and guardians in the prevention of violence and risk behaviors in the lives of Brazilian adolescents.

Factors associated with family violence against adolescents based on the results of the National School Health Survey (PeNSE). / Fatores associados aos episódios de agressão familiar entre adolescentes, resultados da Pesquisa Nacional de Saúde do Escolar (PeNSE).

The study analyzes factors associated with family aggression against adolescents. Data from the National School Health Survey for 2015 were analyzed, and the prevalence of physical aggression per family was calculated according to four blocks. The bivariate analysis was performed, calculating the unadjusted Odds Ratio (OR) within each block and the multivariate regression. Familial aggression was reported by 14.5%. The variables associated with the model were: female, black, yellow, brown, mothers with no higher educational level, adolescent workers (OR 2.10 CI 95% 1.78-2.47). In the family context, they remained associated with aggression, lack of parents "understanding" (OR 1.71 CI95% 1.63 -1.80) and their intrusion into adolescent's privacy (OR 1.80 CI95% 1.70 -1, 91). Report of missing school (OR1.43 CI95% 1.36-1.50). Among the behaviors: smoking (OR 1.23 CI95% 1.12-1.34), alcohol (OR 1.49 CI95% 1.41-1.57), drug experience (OR 1.24 CI95% 1, 15-1,33), early sexual intercourse (OR 1.40 CI95% 1.33 -1.48), reports of loneliness, insomnia and bullying (ORa 2.14 CI95% 2.00-2.30). It is concluded by the association between violence and gender, greater victimization of girls, living in unfavorable social and family contexts.

O estudo analisa fatores associados à agressão familiar contra adolescentes. Foram utilizados dados da Pesquisa Nacional de Saúde dos Escolares 2015 e calculada a prevalência de sofrer agressão física por familiar, segundo quatro blocos de investigação. Procedeu-se a análise bivariada, calculando-se os Odds Ratios (ORs) não ajustados e, por fim, foi realizada a regressão multivariada. A agressão familiar foi referida por 14,5%. Variáveis associadas no modelo mutivariado no bloco sociodemográfico foram: sexo feminino, raça cor preta, amarela, parda, mães sem nível superior de escolaridade, adolescente que trabalham (OR 2,10 IC95% 1,78-2,47). No contexto familiar: a falta de compreensão dos pais (OR 1,71 IC95% 1,63 -1,80) e a intromissão na privacidade dos adolescentes (OR 1,80 IC95% 1,70 -1,91). Relato de faltar às aulas (OR 1,43 IC95% 1,36-1,50). Dentre os comportamentos: tabagismo (OR 1,23 IC95% 1,12-1,34), álcool (OR 1,49 IC95% 1,41-1,57), experiência com drogas (OR 1,24 IC95% 1,15-1,33), relação sexual precoce (OR 1,40 IC95% 1,33 -1,48), relato de solidão, insônia e bullying (ORa 2,14 IC95% 2,00-2,30). Conclui-se pela associação entre violência e gênero, maior vitimização das meninas e adolescentes mais jovens, que vivem em contextos sociais e familiares desfavoráveis.

Fatores associados aos episódios de agressão familiar entre adolescentes, resultados da Pesquisa Nacional de Saúde do Escolar (PeNSE) / Factors associated with family violence against adolescents based on the results of the National School Health Survey (PeNSE)

Resumo O estudo analisa fatores associados à agressão familiar contra adolescentes. Foram utilizados dados da Pesquisa Nacional de Saúde dos Escolares 2015 e calculada a prevalência de sofrer agressão física por familiar, segundo quatro blocos de investigação. Procedeu-se a análise bivariada, calculando-se os Odds Ratios (ORs) não ajustados e, por fim, foi realizada a regressão multivariada. A agressão familiar foi referida por 14,5%. Variáveis associadas no modelo mutivariado no bloco sociodemográfico foram: sexo feminino, raça cor preta, amarela, parda, mães sem nível superior de escolaridade, adolescente que trabalham (OR 2,10 IC95% 1,78-2,47). No contexto familiar: a falta de compreensão dos pais (OR 1,71 IC95% 1,63 -1,80) e a intromissão na privacidade dos adolescentes (OR 1,80 IC95% 1,70 -1,91). Relato de faltar às aulas (OR 1,43 IC95% 1,36-1,50). Dentre os comportamentos: tabagismo (OR 1,23 IC95% 1,12-1,34), álcool (OR 1,49 IC95% 1,41-1,57), experiência com drogas (OR 1,24 IC95% 1,15-1,33), relação sexual precoce (OR 1,40 IC95% 1,33 -1,48), relato de solidão, insônia e bullying (ORa 2,14 IC95% 2,00-2,30). Conclui-se pela associação entre violência e gênero, maior vitimização das meninas e adolescentes mais jovens, que vivem em contextos sociais e familiares desfavoráveis.

Abstract The study analyzes factors associated with family aggression against adolescents. Data from the National School Health Survey for 2015 were analyzed, and the prevalence of physical aggression per family was calculated according to four blocks. The bivariate analysis was performed, calculating the unadjusted Odds Ratio (OR) within each block and the multivariate regression. Familial aggression was reported by 14.5%. The variables associated with the model were: female, black, yellow, brown, mothers with no higher educational level, adolescent workers (OR 2.10 CI 95% 1.78-2.47). In the family context, they remained associated with aggression, lack of parents "understanding" (OR 1.71 CI95% 1.63 -1.80) and their intrusion into adolescent's privacy (OR 1.80 CI95% 1.70 -1, 91). Report of missing school (OR1.43 CI95% 1.36-1.50). Among the behaviors: smoking (OR 1.23 CI95% 1.12-1.34), alcohol (OR 1.49 CI95% 1.41-1.57), drug experience (OR 1.24 CI95% 1, 15-1,33), early sexual intercourse (OR 1.40 CI95% 1.33 -1.48), reports of loneliness, insomnia and bullying (ORa 2.14 CI95% 2.00-2.30). It is concluded by the association between violence and gender, greater victimization of girls, living in unfavorable social and family contexts.

Fatores associados à violência intrafamiliar e solidão entre adolescentes brasileiros / Factors associated with intrafamily violence and loneliness among Brazilian adolescents

Nas últimas décadas observa-se um aumento dos problemas de violência e saúde mental entre os adolescentes, tornando-se as principais causas dos agravos à saúde dessa população. Objetivo: Identificar os fatores associados à violência intrafamiliar e ao sentimento de solidão vivenciados por adolescentes brasileiros. Métodos: Trata-se de um estudo transversal com análise de dados secundários da Pesquisa Nacional de Saúde do Escolar (PeNSE 2015), conduzida pelo IBGE, entre escolares de 13 a 17 anos das escolas públicas e privadas do Brasil. Foi realizada análise descritiva com cálculo da prevalência e intervalos de confiança a 95% da violência intrafamiliar contra o adolescente e do sentimento de solidão relatados pelos estudantes segundo as características sociodemográficas, contexto familiar, estilos de vida e saúde mental. Posteriormente, procedeu-se a regressão logística multinomial, calculando-se a Odds Ratio para a investigação do desfecho de sofrer violência intrafamiliar e a regressão de Poisson com cálculo da Razão de Prevalência para a investigação do desfecho de sentir solidão entre os adolescentes com as variáveis que apresentaram valor de associação p< 0,20 nas análises bivariadas. O nível de significância adotado foi de 5%. Resultados: 5,7% (IC 95%: 5,1 ­ 6,4) dos adolescentes entrevistados relataram terem sofrido violência intrafamiliar uma vez e 7,6% (IC 95%: 6,7 ­ 8,5) relataram sofrer violência intrafamiliar mais de uma vez nos últimos 30 dias. Maior chance de sofrer violência intrafamiliar mais de uma vez foi encontrada entre aqueles com as características: cor da pele preta (ORa = 1,5; IC 95%: 1,1 ­ 2,0), ter insônia (ORa = 1,7; IC 95%: 1,3 ­ 2,1), sofrer bullying raramente ou às vezes (ORa = 1,5; IC 95%: 1,2 ­ 1,8), sofrer bullying na maior parte do tempo (ORa = 3,9; IC 95%: 2,8 ­ 5,3), fazer uso de cigarro (ORa = 2,2; IC 95%: 1,6 ­ 3,0) e consumir bebida alcoólica (ORa = 2,2; IC 95%: 1,7 ­ 2,7). Mostraram-se com menor chance de sofrer mais de uma vez a violência intrafamiliar adolescentes com idade entre 16 a 17 anos (ORa = 0,6; IC 95%: 0,5 ­ 0,8), do sexo feminino (ORa = 0,8; IC 95%: 0,6 ­ 1,0), cujas mães tinham ensino superior completo (ORa = 0,6; IC 95%: 0,5 ­ 0,9), que tinham pais compreensivos (ORa = 0,6; IC 95%: 0,5 ­ 0,7) e eram supervisionados por familiar (ORa = 0,5; IC 95%: 0,4 ­ 0,7). Em relação à solidão,15,5% (IC 95%: 14,5 ­ 16,6) dos estudantes brasileiros relataram esta condição nos últimos 12 meses. Ser do sexo feminino (RPa = 1,6; IC 95%: 1,4 ­ 1,9), a escolaridade materna de nível superior completo (RPa = 1,2; IC 95%: 1,1 ­ 1,4), ter insônia (RPa = 2,8; IC 95%: 2,5 ­ 3,2) e ser vítimas de bullying raramente ou às vezes (RPa = 1,5; IC 95%: 1,3 ­ 1,7) e na maior parte do tempo ou sempre (RPa = 1,9; IC 95%: 1,7 - 2,3) apresentaram maior razão de prevalência de sentir-se só nos doze meses anteriores à 7 pesquisa.Ter amigos (RPa = 0,6; IC 95%: 0,5 - 0,7), fazer refeição com pais ou responsáveis 5 dias ou mais na semana (RPa = 0,7; IC 95%: 0,6 ­ 0,8) e ter pais compreensivos(RPa = 0,5; IC 95%: 0,4 - 0,5) apresentaram menor razão de prevalência no relato de solidão entre os adolescentes. Conclusão: A violência intrafamiliar contra o adolescente está relacionada às condições de desigualdades sociais, uso de substâncias psicoativas, vivência de situações de violência no ambiente escolar e no contexto familiar. Já a solidão entre os adolescentes se associa ao sexo, ao apoio social e familiar, a violência intrafamiliar e a comportamentos de risco como o consumo de bebida alcoólica e bullying, tornando-se frequente nos relatos dos adolescentes. Deve-se investir em políticas voltadas para a promoção do bem estar físico e mental nessa faixa etária, como promover a relação de amizade e participação da família na vida dos adolescentes.(AU)

INTRODUCTION: In the last decades, there has been an increase in the problems of violence and mental health among adolescents, becoming the main causes of the health problems of this population. OBJECTIVE: To identify the factors associated with intrafamily violence and the feeling of loneliness experienced by Brazilian adolescents. METHODS: This is a crosssectional study with secondary data analysis from the National Adolescent School-based Health Survey (PeNSE 2015), conducted by IBGE, among students aged 13 to 17 years of public and private schools in Brazil. Descriptive analysis was carried out with a calculation of the prevalence and 95% confidence intervals of intrafamily violence against adolescents and feelings of loneliness reported by students according to sociodemographic characteristics, family context, life styles and mental health. Subsequently, multinomial logistic regression was performed, calculating the Odds Ratio for the investigation of the outcome of suffering intrafamily violence and the Poisson regression with calculation of the Prevalence Ratio for the investigation of the outcome of feeling loneliness among adolescents with the variables which presented association value p <0.20 in the bivariate analyzes. The level of significance was 5%. RESULTS: 5.7% (CI 95%: 5.1 - 6.4) of adolescents interviewed had suffered intrafamily violence at one time and 7.6% (95% CI: 6.7 - 8.5) related to violence more than once in the last 30 days. The highest chance of suffering intrafamily violence was more than once among those with characteristics: black skin color (ORa = 1,5, 95% CI: 1.1 - 2.0), having insomnia (ORa = 1.7; 95% CI: 1.3 - 2.1), suffer from bullying rarely or sometimes (ORa = 1,5, 95% CI: 1.2 - 1.8), suffer from bullying (ORa = 3,9, 95% CI: 2,8-5,3), make use of cigarettes (ORa = 2,2, 95% CI: 1,6-3,0) and consume alcoholic beverage (ORa = 2.2 95% CI: 1, 7-2.7). Compared with adolescents aged 16 to 17 years (ORa = 0.6, 95% CI 0.5-0.8), the female sex (ORa = 0.8, 95% CI: 0.6 - 1.0), whose mothers had completed tertiary education (ORa = 0.6, 95% CI: 0.5-0.9), who were comprehensive parents (ORa = 0.6, 95% CI: 0.5-0.7) and were supervised by relatives (ORa = 0.5; 95% CI: 0.4-0.7). Regarding solitude, 15.5% (95% CI: 14.5 - 16.6) of Brazilian students reported this condition in the last 12 months. Being female (RP = 1.6, 95% CI 1.4-1.9), the highest maternal level of education (RP = 1.2, 95% CI 1.1 - 1.4), having insomnia (RPa = 2.8, 95% CI: 2.5-3.2), and to be victims of bullying rarely or sometimes (RPa = 1.5; 95% CI: 1.3 - 1.7) and most of the time or always (RPa = 1.9, 95% CI: 1.7 - 2.3) had a higher prevalence rate of feeling only in the 12 months prior to the survey. Having friends (RPa = 0.6, 95% CI 0.5-0.7), having a meal with parents or guardians 5 days or more in the week (RPa = 0.7, 95% CI: 0.6-0 , 8) and having 9 comprehensive parents (RPa = 0.5, 95% CI: 0.4 - 0.5) had a lower prevalence ratio in the report of solitude among adolescents. CONCLUSION: Intrafamily violence against adolescents is related to the conditions of social inequalities, the use of psychoactive substances, the experience of situations of violence in the school environment and in the family context. Already the solitude among adolescents is associated with sex, social and family support, intrafamily violence and risk behaviors such as alcohol consumption and bullying, becoming frequent in adolescents' reports. It is necessary to invest in policies aimed at promoting physical and mental well-being of adolescents, such as promoting the relationship of friendship and family participation in adolescents' lives.(AU) I

Crioterapia em modelo de compressão do nervo isquiático: análise funcional e morfológica / Cryotherapy in sciatic nerve compression model: functional and morphological analysis / Crioterapia en modelo de compresión del nervio ciático: análisis funcional y morfológico

RESUMO Introdução: A crioterapia é uma modalidade terapêutica que visa reduzir processos álgicos e inflamatórios, sendo que a imersão é considerada a forma mais eficaz; no entanto, a literatura apresenta possíveis efeitos deletérios com relação à aplicação da crioterapia em nervos superficiais. Objetivo: Avaliar o efeito da crioterapia em modelo experimental de compressão do nervo isquiático em ratos Wistar, por meio de análise funcional e morfológica. Métodos: Foram utilizados 42 ratos, sendo seis animais por grupo: G1 - controle, submetido à eutanásia no 15º dia de pós-operatório (PO); G2, G3 e G4 - submetidos à compressão do nervo isquiático, submetidos à eutanásia no 3º, 8º e 15º dias de PO, respectivamente; G5, G6 e G7 - submetidos à compressão do nervo isquiático e tratados com crioterapia, submetidos à eutanásia no 3º, 8º e 15º dias de PO, respectivamente. As avaliações do índice funcional do isquiático (IFC) e do teste de incapacidade funcional aconteceram nos momentos pré-lesão, no 2º de PO e no dia da eutanásia em cada grupo com lesão. Após o período de intervenção, os animais foram devidamente anestesiados e o nervo isquiático distal ao procedimento de compressão foi dissecado e coletado para análise morfológica. A análise estatística foi realizada pelo teste de ANOVA mista, com nível de significância de 5%. Resultados: Houve diminuição do IFC após a lesão e o teste de incapacidade funcional mostrou aumento do tempo de elevação da pata. Com relação à análise morfológica, o G1 apresentou fibras nervosas com aspecto normal e nos grupos com lesão houve degeneração nervosa, sendo que o G6 teve uma discreta recuperação das fibras nervosas, além de leve regeneração no G4 e G7. Conclusão: A crioterapia não foi eficaz para recuperar os parâmetros funcionais analisados, entretanto, houve discreta melhora dos aspectos morfológicos do grupo submetido à eutanásia no 8º dia de PO. Nível de Evidência II; Estudos terapêuticos - Investigação dos resultados do tratamento.

ABSTRACT Introduction: Cryotherapy is a therapeutic modality that aims to reduce inflammatory and painful processes, with immersion being considered the most effective form; however, the literature has possible deleterious effects related to the application of cryotherapy to superficial nerves. Objective: To evaluate the effect of cryotherapy in experimental model of sciatic nerve compression in Wistar rats, through morphologic and functional analysis. Methods: Forty-two rats were used, six animals per group: G1 - control euthanized on the 15th postoperative day (PO); G2, G3 and G4 - submitted to sciatic nerve compression, euthanized at 3rd, 8th and 15th PO days, respectively; G5, G6 and G7 - submitted to sciatic nerve compression and treated with cryotherapy, euthanized at 3rd, 8th and 15th PO days, respectively. The assessments of sciatic functional index (SFI) and the functional disability test took place at the pre-injury, 2nd PO and on the day of euthanasia in each group with injury. After the intervention period, the animals were anesthetized properly and the sciatic nerve distal to the compression procedure was dissected and collected for morphological analysis. Statistical analysis was by the mixed ANOVA test with a significance level of 5%. Results: There was a decrease of SFI after injury and the functional disability test showed an increase in paw elevation time. Regarding the morphological analysis, the G1 showed normal nerve fibers and in the groups with lesion, there was nerve degeneration, G6 had a slight recovery of the nerve fibers, besides mild regeneration in G4 and G7. Conclusion: Cryotherapy was not effective to recover the functional parameters analyzed; however, there was a slight improvement in the morphological aspects of the group euthanized on the 8th PO day. Level of Evidence II; Therapeutic studies - Investigating the results of treatment.

RESUMEN Introducción: La crioterapia es una modalidad terapéutica que busca reducir procesos de dolor e inflamatorios, siendo que la inmersión es considerada la forma más eficaz; sin embargo, la literatura presenta posibles efectos deletéreos con relación a la aplicación de la crioterapia en nervios superficiales. Objetivo: Evaluar el efecto de la crioterapia en modelo experimental de compresión del nervio ciático en ratas Wistar, por medio de análisis funcional y morfológico. Métodos: Se utilizaron 42 ratas, siendo seis animales por grupo: G1 - control, sometido a la eutanasia en el 15º día de postoperatorio (PO); G2, G3 y G4 - sometidos a la compresión del nervio ciático, sometidos a la eutanasia en los 3º, 8º y 15º días de PO, respectivamente; G5, G6 y G7 - sometidos a la compresión del nervio ciático y tratados con crioterapia, sometidos a la eutanasia en los 3º, 8º y 15º días de PO, respectivamente. Las evaluaciones del índice funcional del ciático (IFC) y la prueba de incapacidad funcional ocurrieron en los momentos pre-lesión, en el 2º día de PO y el día de la eutanasia en cada grupo con lesión. Después del período de intervención, los animales fueron debidamente anestesiados y el nervio ciático distal al procedimiento de compresión fue disecado y recogido para análisis morfológico. El análisis estadístico fue realizado por la prueba de ANOVA mixta, con un nivel de significancia del 5%. Resultados: Hubo disminución del IFC después de la lesión y la prueba de incapacidad funcional mostró aumento del tiempo de elevación de la pata. En cuanto al análisis morfológico, el G1 presentó fibras nerviosas con aspecto normal y en los grupos lesionados hubo degeneración nerviosa, siendo que el G6 tuvo una discreta recuperación de las fibras nerviosas, además de ligera regeneración en el G4 y G7. Conclusión: La crioterapia no fue eficaz para recuperar los parámetros funcionales analizados, sin embargo, hubo discreta mejora de los aspectos morfológicos del grupo sometido a la eutanasia en el 8º día de PO. Nivel de Evidencia II; Estudios terapéuticos - Investigación de los resultados del tratamento.

Action of vanillin (Vanilla planifolia) on the morphology of tibialis anterior and soleus muscles after nerve injury.

OBJECTIVE: To evaluate the action of vanillin (Vanilla planifolia) on the morphology of tibialis anterior and soleus muscles after peripheral nerve injury. METHODS: Wistar rats were divided into four groups, with seven animals each: Control Group, Vanillin Group, Injury Group, and Injury + Vanillin Group. The Injury Group and the Injury + Vanillin Group animals were submitted to nerve injury by compression of the sciatic nerve; the Vanillin Group and Injury + Vanillin Group, were treated daily with oral doses of vanillin (150mg/kg) from the 3rd to the 21st day after induction of nerve injury. At the end of the experiment, the tibialis anterior and soleus muscles were dissected and processed for light microscopy and submitted to morphological analysis. RESULTS: The nerve compression promoted morphological changes, typical of denervation, and the treatment with vanillin was responsible for different responses in the studied muscles. For the tibialis anterior, there was an increase in the number of satellite cells, central nuclei and fiber atrophy, as well as fascicular disorganization. In the soleus, only increased vascularization was observed, with no exacerbation of the morphological alterations in the fibers. CONCLUSION: The treatment with vanillin promoted increase in intramuscular vascularization for the muscles studied, with pro-inflammatory potential for tibialis anterior, but not for soleus muscle. OBJETIVO: Avaliar a ação da vanilina (Vanilla planifolia) sobre a morfologia dos músculos tibial anterior e sóleo após lesão nervosa periférica. MÉTODOS: Ratos Wistar foram divididos em quatro grupos, com sete animais cada, sendo Grupo Controle, Grupo Vanilina, Grupo Lesão e Grupo Lesão + Vanilina. Os animais dos Grupos Lesão e Grupo Lesão + Vanilina foram submetidos à lesão nervosa por meio da compressão do nervo isquiático, e os Grupos Vanilina e Grupo Lesão + Vanilina foram tratados diariamente com doses orais de vanilina (150mg/kg) do 3o ao 21o dia após a indução da lesão nervosa. Ao término do experimento, os músculos tibial anterior e sóleo foram dissecados e seguiram o processamento de rotina em microscopia de luz, para posterior análise morfológica. RESULTADOS: A compressão nervosa promoveu alterações morfológicas características de denervação, sendo que o tratamento com vanilina foi responsável por respostas distintas nos músculos estudados. Para o tibial anterior, houve aumento do número de células satélites, núcleos centrais e atrofia das fibras, bem como desorganização fascicular. Já no sóleo, houve apenas aumento da vascularização, sem exacerbação das alterações morfológicas nas fibras. CONCLUSÃO: O tratamento com vanilina promoveu o aumento da vascularização intramuscular para os músculos estudados, com potencial pró-inflamatório para o tibial anterior, o que não ocorreu no músculo sóleo.

A Readiness Ruler for Assessing Motivation to Change in People with Eating Disorders.

OBJECTIVE: We examined the psychometric properties of the Eating Disorder Readiness Ruler a simple self-report instrument designed to enable rapid assessment of readiness to change problematic eating behaviours in people with clinical eating disorders. METHOD: We administered the ED-RR, the Eating Disorders Examination Questionnaire and a measure of autonomous and controlled motivation for change to 206 individuals receiving outpatient treatment for an eating disorder. RESULTS: A principal axis factoring analysis of the ED-RR yielded a significant two-factor solution (explaining 59% of variance)-one factor pertaining to restriction and body image preoccupation (four items), the other to binge-eating and vomiting symptoms (two items). The ED-RR showed good internal consistency (alpha coefficients for the two factors being .77 and .84 respectively). Furthermore, individuals reporting higher readiness showed higher scores on independent measures of autonomous motivation and greater symptom reductions over time. DISCUSSION: Results suggest that the ED-RR is a psychometrically sound tool with potential clinical utility. Copyright © 2017 John Wiley & Sons, Ltd and Eating Disorders Association.

Action of vanillin (Vanilla planifolia) on the morphology of tibialis anterior and soleus muscles after nerve injury / Ação da vanilina (Vanilla planifolia) sobre a morfologia dos músculos tibial anterior e sóleo após lesão nervosa

ABSTRACT Objective To evaluate the action of vanillin (Vanilla planifolia) on the morphology of tibialis anterior and soleus muscles after peripheral nerve injury. Methods Wistar rats were divided into four groups, with seven animals each: Control Group, Vanillin Group, Injury Group, and Injury + Vanillin Group. The Injury Group and the Injury + Vanillin Group animals were submitted to nerve injury by compression of the sciatic nerve; the Vanillin Group and Injury + Vanillin Group, were treated daily with oral doses of vanillin (150mg/kg) from the 3rd to the 21st day after induction of nerve injury. At the end of the experiment, the tibialis anterior and soleus muscles were dissected and processed for light microscopy and submitted to morphological analysis. Results The nerve compression promoted morphological changes, typical of denervation, and the treatment with vanillin was responsible for different responses in the studied muscles. For the tibialis anterior, there was an increase in the number of satellite cells, central nuclei and fiber atrophy, as well as fascicular disorganization. In the soleus, only increased vascularization was observed, with no exacerbation of the morphological alterations in the fibers. Conclusion The treatment with vanillin promoted increase in intramuscular vascularization for the muscles studied, with pro-inflammatory potential for tibialis anterior, but not for soleus muscle.

RESUMO Objetivo Avaliar a ação da vanilina (Vanilla planifolia) sobre a morfologia dos músculos tibial anterior e sóleo após lesão nervosa periférica. Métodos Ratos Wistar foram divididos em quatro grupos, com sete animais cada, sendo Grupo Controle, Grupo Vanilina, Grupo Lesão e Grupo Lesão + Vanilina. Os animais dos Grupos Lesão e Grupo Lesão + Vanilina foram submetidos à lesão nervosa por meio da compressão do nervo isquiático, e os Grupos Vanilina e Grupo Lesão + Vanilina foram tratados diariamente com doses orais de vanilina (150mg/kg) do 3o ao 21o dia após a indução da lesão nervosa. Ao término do experimento, os músculos tibial anterior e sóleo foram dissecados e seguiram o processamento de rotina em microscopia de luz, para posterior análise morfológica. Resultados A compressão nervosa promoveu alterações morfológicas características de denervação, sendo que o tratamento com vanilina foi responsável por respostas distintas nos músculos estudados. Para o tibial anterior, houve aumento do número de células satélites, núcleos centrais e atrofia das fibras, bem como desorganização fascicular. Já no sóleo, houve apenas aumento da vascularização, sem exacerbação das alterações morfológicas nas fibras. Conclusão O tratamento com vanilina promoveu o aumento da vascularização intramuscular para os músculos estudados, com potencial pró-inflamatório para o tibial anterior, o que não ocorreu no músculo sóleo.

Ação do exercício de subida em escada com sobrecarga na morfologia do músculo tibial anterior de ratos Wistars após axonotmese / Action of the climbing ladder exercise with overload in the morphology of the anterior tibial muscle of wistars rats after axonotmesis

Objetivo: avaliar histomorfometrica e morfologicamente o músculo tibial anterior de ratos submetidos à axonotmese e tratados com exercício. Métodos: foram randomizados 28 ratos Wistar nos grupos controle (GC), exercício (GE), lesão (GL) e lesão+exercício (GLE). No terceiro dia após compressão, GE e GLE realizaram exercício de subida em escada, com duas séries de dez repetições. Após 21 dias, o músculo tibial anterior foi processado para microscopia de luz. Resultados: Na análise morfológica GC apresentou morfologia com aspecto característico, GE hipertrofia muscular, GL alterações morfológicas, como fibras polimórficas e núcleos centrais, e GLE aspecto semelhante ao controle, porém com algumas alterações. Na área de secção transversa e menor diâmetro das fibras GC e GE apresentaram valores maiores, o inverso da análise de vasos sanguíneos. Para o tecido conjuntivo, GE apresentou-se menor que o GL. Conclusão: O protocolo de exercício promoveu melhora nos aspectos histomorfológicos, mas não reverteu totalmente os efeitos deletérios. (AU)

Objective: to evaluate morphologically the tibialis anterior muscle of rats submitted to axonotmosis and treated with exercise. Methods: 28 Wistar rats were used in groups control (CG), exercise (GE), injury (GL) and injury + exercise (GLE). On the third day after compression, GE and GLE performed climb exercise staircase, with two sets of ten repetitions. After 21 days, the muscle was processed for light microscopy. Results: In the morphological analysis GC presented with morphology characteristic appearance, GE muscle hypertrophy, GL morphological changes like polymorphic fibers and central nucleo, and GLE look similar to the control, but with some changes morphological. In the cross-sectional area and smaller diameter of the GC and GE fiber showed higher values, inversed analysis of blood vessels. For the connective tissue, GE was lower than the GL. Conclusion: Summing up, the exercise promoted improvement in morphological aspects, but not totally reversed the deleterious effects of denervation. (AU)

Resistance exercise recovers the structure of cartilage and synovial membrane of the ankle joint of rats after sciatic compression

Aim: to determine the effects of sciatic compression and treatment with resistance exercise on the morphology of the ankle joint of Wistar rats. Methods: 32 male rats, aged 10 ± 1 week, weighing 376±22 grams were divided into the following four groups (n=8/group): CG (control), LG (lesion), EG (exercise) and LEG (lesion and exercise). Three days after sciatic compression, the animals in the EG and LEG were submitted to resistance exercise by climbing stairs (five days/week) for three weeks and a load of 100 grams was added. The exercise was carried out in two sets of ten consecutive ascents of the steps. The ankle joint tissues were analyzed for their morphometry and morphology using light microscopy. Results: Regarding the number of chondrocytes, the LG and EG had more cells in the anterior articular cartilage in the tibia (62 and 43%) and in the talus (57 and 45%) when compared to the CG. In the LEG there was a 25% and 26% reduction of chondrocytes in the anterior cartilage in the tibia and talus when compared to the LG. Changes were observed in the tibia and talus in the LG, with the presence of flocculation, invagination of the subchondral bone, discontinuity of tidemark and pannus covering the subchondral bone in the talus, as well as changes in the synovial membrane. These alterations were minimized in the articular cartilage and synovial membrane in the LEG. Conclusions exercise restores the tissue morphology of ankle joint in Wistar rats after sciatic compression.(AU)

Nociceptive and Neuronal Evaluation of the Sciatic Nerve of Wistar Rats Subjected to Compression Injury and Treated with Resistive Exercise.

Background. To investigate the climb stairs resistance exercise on nociception and axonal regeneration in the sciatic nerve of rats. Methods. 24 Wistar rats were divided: control group (CG-no injury), exercise group (EG-no injury with physical exercise), lesion group (LG-injury, but without exercise), and treated group (LEG-injury and physical exercise). LG and LEG were subjected to sciatic nerve compression with hemostat. From the 3rd day after injury began treatment with exercise, and after 22 days occurs the removal of a nerve fragment for morphological analysis. Results. Regarding allodynia, CG obtained values less than EG (p = 0.012) and larger than LG and LEG (p < 0.001). Histological results showed that CG and EG had normal appearance, as LG and LEG showed up with large amounts of inflammatory infiltration, degeneration and disruption of nerve fibers, and reduction of the myelin sheath; however LEG presented some regenerated fibers. From the morphometric data there were significant differences, for nerve fiber diameter, comparing CG with LG and LEG and comparing axon diameter and the thickness of the myelin of the CG to others. Conclusion. Climb stairs resistance exercise was not effective to speed up the regenerative process of axons.

Evaluation of nociception and edema in experimental sciatic nerve compression model in Wistar rats treated with cryotherapy / Avaliação da nocicepção e edema em modelo experimental de compressão do nervo isquiático em ratos Wistar tratados com crioterapia

ABSTRACT BACKGROUND AND OBJECTIVES: Considering the scarcity of studies addressing cryotherapy to treat peripheral nervous injuries, this study aimed at evaluating nociception and edema in an experimental sciatic nerve compression model with Wistar rats treated with cryotherapy. METHODS: Forty-two rats were randomly distributed in groups: G1 - control, euthanized in the 15th postoperative day; G2, G3 and G4 - submitted to sciatic nerve compression and euthanized in the 3rd, 8th and 15th postoperative day, respectively; G5, G6 and G7 - submitted to sciatic nerve compression and treated with cryotherapy, euthanized in the 3rd, 8th and 15th postoperative day, respectively. Nociception evaluation at injury site and plantar region, and observation of edema were performed before injury, in the 2nd postoperative day and in the day corresponding to euthanasia of each injured group. Mixed ANOVA was used for statistical analysis, considering significant 5%. RESULTS: There has been decreased pain threshold at injury site in injured groups, however there has been increase in the same groups with regard to evaluations in the 8th and 15th postoperative days. Nociception in the plantar region was similar to previous one, however threshold has not increased. With regard to edema, there has been significant difference in evaluations in the 3rd and 2nd postoperative days corresponding to G1, G4 and G7, which had higher values as compared to pre-injury. CONCLUSION: Cryotherapy has not increased nociceptive threshold or decreased the edema.

RESUMO JUSTIFICATIVA E OBJETIVOS: Considerando a carência de estudos a respeito da crioterapia como tratamento de lesão nervosa periférica, este estudo teve como objetivo avaliar a nocicepção e o edema em modelo experimental de compressão do nervo isquiático em ratos Wistar, tratados com crioterapia. MÉTODOS: Foram utilizados 42 ratos separados aleatoriamente nos grupos: G1 - controle, eutanasiado no 15º de pós-operatório; G2, G3 e G4 - submetidos à compressão do nervo isquiático, eutanasiados no 3º, 8º e 15º de pós-operatório, respectivamente; G5, G6 e G7 - submetidos à compressão do nervo isquiático e tratados com crioterapia, eutanasiados no 3º, 8º e 15º de pós-operatório, respectivamente. As avaliações da nocicepção no local da lesão e na região plantar, e a verificação do edema aconteceram nos momentos pré-lesão, 2º dia de pós-operatório e no dia correspondente a eutanásia de cada grupo lesionado. A análise estatística foi pela ANOVA mista, com nível de significância de 5%. RESULTADOS: No local da lesão houve diminuição do limiar doloroso nos grupos lesionados, entretanto, apresentou aumento do mesmo nos grupos relacionados às avaliações do 8º e 15º de pós-operatório. Já a nocicepção realizada na região plantar foi semelhante à anterior, porém o limar não aumentou. Com relação ao edema, houve diferença significativa na avaliação realizada no 3º e no 2º dias de pós-operatório correspondentes ao G1, G4 e G7, que apresentaram valores maiores comparadas com a pré-lesão. CONCLUSÃO: A crioterapia não auxiliou no aumento do limiar nociceptivo e redução de edema.

Efeito do exercício resistido na redução do edema, nocicepção e regeneração nervosa em um modelo de compressão do nervo isquiático / Effect of resistance training on the reduction of edema, nociception, and nerve regeneration in a sciatic nerve compression model

OBJETIVOS: Analisar os efeitos do exercício físico resistido de subida em escada, sobre o edema, nocicepção e regeneração nervosa de ratos Wistar, submetidos à compressão do nervo isquiático. MÉTODOS: Foram estudados 24 ratos Wistar, divididos igualmente entre quatro grupos: Grupo Controle, Grupo Exercício, Grupo Lesão e Grupo Tratado ­ Lesão e Exercício. O Grupo Lesão e o Grupo Tratado foram submetidos à compressão do nervo isquiático com pinça hemostática por 30 segundos. A partir do terceiro dia após a lesão, iniciou-se o tratamento com exercício resistido de subida em escada para o Grupo Exercício e o Grupo Tratado. O tratamento consistiu em realizar duas séries de 10 subidas na escada, com sobrecarga de 100 gramas e intervalo de um minuto entre uma série e outra. O estudo foi conduzido por 22 dias e nesse tempo os animais foram avaliados quanto ao edema e à nocicepção. No 22º dia de pós-operatório, os animais foram anestesiados para retirada de um fragmento do nervo isquiático para análise do número de axônios e da densidade de fibras. Em seguida, ainda sob efeito da anestesia, os animais foram eutanasiados. Os nervos coletados seguiram protocolo de processamento histológico de rotina. As expressões do Fator de Crescimento Neural e do Fator de Crescimento Derivado do Cérebro foram avaliadas por Western blotting. RESULTADOS: Não houve diferença significativa entre os grupos no tamanho do edema. O Grupo Controle apresentou maior limiar nociceptivo comparado aos demais grupos. A análise morfométrica não revelou diferença significativa entre os grupos, quanto à quantidade de axônios e à densidade de fibras. A expressão do Fator de Crescimento Derivado do Cérebro foi maior no Grupo Lesão e no Grupo Tratado quando comparados ao Grupo Controle. CONCLUSÕES: O exercício físico resistido de subida em escada, nos parâmetros propostos, não foi eficaz para reduzir o edema, a nocicepção ou aumentar o número de axônios e a densidade de fibras nervosas após lesão do nervo isquiático.

AIMS: To analyze the effects of ladder-climbing resistance training exercise on edema, nociception, and regeneration of the sciatic nerve in Wistar rats subjected to sciatic nerve compression. METHODS: Twenty-four Wistar rats were divided into four groups: Control Group, Exercise Group, Injury Group, and Treated Group (injury and exercise). Injury Group and Treated Group were subjected to sciatic nerve compression with a hemostat for 30 seconds. On the third day after injury, Exercise Group and Treated Group began treatment with ladder-climbing resistance exercise. The treatment consisted in performing two series of 10 ladder climbs with a 100-gram overload and a one-minute interval between the series. The study was conducted for 22 days, during which time the animals were evaluated for edema and nociception. Twenty-two days after surgery, the animals were anesthetized for removal of a sciatic nerve fragment and analysis of the number of axons and fiber density. Thereafter, still under anesthesia, the animals were euthanized. Nerve sampling followed the routine histological processing protocol. Expressions of Neural Growth Factor and Brain-derived Neurotrophic Factor were evaluated by Western blotting. RESULTS: There was no significant difference in edema size between groups. Control Group showed the highest nociceptive threshold compared to the other groups. The morphometric analysis showed no significant difference in number of axons and fiber density between groups. The expression of Brain-derived Neurotrophic Factor was greater in the Injury Group and the Treated Group compared to the Control Group. CONCLUSIONS: The proposed ladder-climbing resistance training was not effective in reducing edema and nociception or in increasing the number of axons and fiber density after sciatic nerve injury.