[The organizational aspects of health care of students of institutions of higher professional education].

In recent decades, both in the Russian Federation and in the Sverdlovsk oblast decreasing of population size of adolescents and deterioration of their physical development and health status were established. In Russia, the organization of medical care of college students is insufficiently organized and requires additional improvements. The selective assessment of activities of medical offices in six colleges in Yekaterinburg was implemented. The sociological surveys were organized on the basis of the international HBSC questionnaire to study opinions of the minors about organization of medical care in colleges (653 students interviewed) and prevalence of health risk factors among students (1142 students were interviewed). In the Sverdlovsk region in 2018, only 53.6% of colleges were licensed for carrying out medical activities. According to the study, medical care in colleges was provided by medical assistant of medical office. This condition resulted in that not all the students underwent preventive examinations or underwent them not in required fullness. The medical personnel of colleges provided no analysis of health status of adolescents and health education is insufficient. The analysis of the data of sociological surveys established high prevalence of behavioral risk factors among underage students. Almost half of respondents noted the presence of harmful habits and only quarter of respondents paid attention to healthy diet. The percentage of respondents claimed that they tasted and consumed "spices" and "surfactants" was high against the background of low awareness of dangers of these habits. To amend this situation, it is necessary to organize auditing of quality of medical care of students in colleges, to analyze quality of preventive examinations, to develop a set of preventive measures of promoting health of students of colleges, based on their motivation and psychological characteristics, involving students themselves in the process, applying interactive forms.

[Structural-dynamic and functional properties of native and modified streptokinase]. / Strukturno-dinamicheskie i funktsional'nye svoistva nativnoi i modifitsirovannoi streptokinazy.

The process of streptokinase modification by a polymer and the dynamics of protein molecules and the polymer in a protein-polymer (dialdehyde dextran, DAD) conjugate were studied with the aid of luminescent methods. Conclusions were drawn on the structure of the protein-DAD conjugate and the selection of optimum conditions for the preparation of modified streptokinase. It is shown that modified streptokinase is more stable to the action of denaturating agents. The interaction between streptokinase and plasminogen activated by it and changes in the streptokinase-plasminogen complex for modified streptokinase were detected.