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Fetal Diagn Ther ; 25(1): 3-7, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19077423

RESUMO

OBJECTIVE: To verify the correlation between fetal splenic artery Doppler velocimetry and fetal hemoglobin (Hb) levels in Rh alloimmunization. METHODS: Splenic artery Doppler peak systolic velocity (PSV) and pulsatility index (PI) were obtained before cordocentesis in rhesus-alloimmunized fetuses. Doppler was performed before 80 cordocentesis in 36 patients between 20 and 35 weeks of gestation. Mild, moderate and severe anemia were defined as a Hb deficit of >or=2, >or=5 and >or=7 g/dl respectively. RESULTS: Anemia was noted in 64% of the fetuses and moderate and severe anemia in 18 and 21%. Splenic artery PSV was higher in groups with moderate (p = 0.001) and severe (p < 0.000) anemia but not in the group with mild anemia (p = 0.189) when compared to non-anemic fetuses. Splenic artery PI was higher only in the severely anemic group (p = 0.001). CONCLUSIONS: The splenic artery PI and PSV are higher in fetuses with severe anemia.


Assuntos
Anemia/embriologia , Doenças Fetais/fisiopatologia , Isoimunização Rh/complicações , Artéria Esplênica/fisiopatologia , Adulto , Anemia/diagnóstico por imagem , Anemia/fisiopatologia , Velocidade do Fluxo Sanguíneo , Cordocentese , Feminino , Doenças Fetais/diagnóstico por imagem , Doenças Fetais/etiologia , Humanos , Fluxometria por Laser-Doppler , Gravidez , Artéria Esplênica/diagnóstico por imagem , Ultrassonografia
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