Tongue Metastasis of Mucinous Colorectal Adenocarcinoma: Report of a Rare Case.

Metastases in the oral and maxillofacial region, particularly in soft tissues, are exceedingly rare. Such metastases can present as swelling in older individuals, especially in the tongue and gingiva. Furthermore, colorectal metastases at this site are commonly found in the mandible and gingiva and usually share the same morphology as the primary tumor. Herein, we report the case of a 61-year-old woman with a metastatic nodule in the tongue covered by normal mucosa. The clinical, histopathological, and immunohistochemical findings were essential for the final diagnosis of colorectal metastasis, consistent with adenocarcinoma with mucinous differentiation and intestinal phenotype. Metastases of colorectal adenocarcinoma to the tongue are rare but should be included in the differential diagnosis of nodular lesions at this site. The diagnosis can therefore be made based on meticulous clinical and histopathological examination complemented by immunohistochemistry.

Efeito da clorexidina e do laser de baixa potência na prevenção e no tratamento da mucosite oral / Effect of chlorhexidine and low power laser in the prevention and treatment of oral mucositis

Introdução: A mucosite oral é um dos efeitos colaterais mais frequentes do tratamento oncológico, sendo responsável pelo maior declínio na qualidade de vida dos pacientes e causando importante morbidade. Objetivo: Este estudo tem como objetivo avaliar o efeito preventivo da clorexidina e o efeito terapêutico do laser de baixa potência em pacientes sob terapia antineoplásica, nos centros de oncologia da cidade de Feira de Santana, Estado da Bahia. Material e método: Foram avaliados 74 pacientes em tratamento quimio e/ou radioterápico, divididos em quatro grupos: grupo experimental I (n = 37), pacientes submetidos a bochechos com digluconato de clorexidina; grupo experimental II (n = 07), pacientes com mucosite oral submetidos a bochechos com digluconato de clorexidina e ao laser de baixa potência; grupo controle I (n = 37), pacientes submetidos ao protocolo dos centros de oncologia, e grupo controle II (n  =  15), pacientes com mucosite submetidos ao protocolo dos centros de oncologia. Cada paciente foi avaliado ao final do tratamento, por meio de exame local, para detecção de mucosite. Resultado: Dos 74 pacientes, 22 desenvolveram mucosite, sendo 07 dos grupos controles (I e II) e 15 dos grupos experimentais (I e II). Dos pacientes que desenvolveram mucosite, 07 foram tratados com o laser. Conclusão: A solução de clorexidina não preveniu a instalação da mucosite oral, apesar de ter diminuído a gravidade das lesões. Com relação ao tempo de permanência das lesões, observou-se a importância do uso do laser no manejo da mucosite (p = 0,0106).

Background: The oral mucositis is one of the most frequent side effects of oncology treatment and is responsible for the largest decline in quality of life of patients and causing significant morbidity. Objective: This study aimed to evaluate the preventive effect of chlorhexidine and treatment of low-energy laser in patients under antineoplastic therapy in three oncology centers in the city of Feira de Santana, Bahia. Material and method: 74 patients were evaluated on chemotherapy or radiotherapy treatment, divided into four groups: experimental group I (n = 37), patients undergoing mouthwash with chlorhexidine digluconate; experimental group II (n = 07), patients with oral mucositis undergoing mouthwashes with chlorhexidine digluconate and low laser power, control group I (n = 37), submitted to the protocol of the centers of oncology and control group II (n = 15) patients with mucositis protocol submitted to the centers of oncology. Each patient was evaluated at the end of treatment by local examination for the detection of oral mucositis. Result: From 74 patients, 22 developed mucositis, where 07 of the control groups and 15 of experimental groups. From patients who developed mucositis, 07 were treated by laser. Conclusion: The chlorhexidine did not prevent the installation of oral mucositis, although it decreased the severity of injuries. Regarding the time of permanence of the injuries, the value found (p = 0.0106) demonstrated the importance of laser using in the management of oral mucositis.