Floristic Similarities between the Lichen Flora of Both Sides of the Drake Passage: A Biogeographical Approach.

This paper analyses the lichen flora of Navarino Island (Tierra del Fuego, Cape Horn Region, Chile), identifying species shared with the South Shetland Islands (Antarctic Peninsula). In this common flora, species are grouped by their biogeographic origin (Antarctic-subantarctic endemic, austral, bipolar, and cosmopolitan), their habitat on Navarino Island (coastal, forest, and alpine), their morphotype (crustaceous, foliaceous, fruticulose, and cladonioid), and the substrate from which they were collected (epiphytic, terricolous and humicolous, and saxicolous). A total of 124 species have been recognised as common on both sides of the Drake Passage, predominantly bipolar, crustaceous, and saxicolous species, and with an alpine distribution on Navarino Island. The most interesting fact is that more than 30% of the flora is shared between the southern tip of South America and the western Antarctic Peninsula, which is an indication of the existence of a meridian flow of propagules capable of crossing the Antarctic polar front.

Retinal pigment epithelium degeneration caused by aggregation of PRPF31 and the role of HSP70 family of proteins.

BACKGROUND: Mutations in pre-mRNA splicing factor PRPF31 can lead to retinitis pigmentosa (RP). Although the exact disease mechanism remains unknown, it has been hypothesized that haploinsufficiency might be involved in the pathophysiology of the disease. METHODS: In this study, we have analyzed a mouse model containing the p.A216P mutation in Prpf31 gene. RESULTS: We found that mutant Prpf31 protein produces cytoplasmic aggregates in the retinal pigment epithelium and decreasing the protein levels of this splicing factor in the nucleus. Additionally, normal protein was recruited in insoluble aggregates when the mutant protein was overexpressed in vitro. In response to protein aggregation, Hspa4l is overexpressed. This member of the HSP70 family of chaperones might contribute to the correct folding and solubilization of the mutant protein, allowing its translocation to the nucleus. CONCLUSIONS: Our data suggests that a mechanism haploinsufficiency and dominant-negative is involved in retinal degeneration due to mutations in PRPF31. HSP70 over-expression might be a new therapeutic target for the treatment of retinal degeneration due to PRPF31 mutations.

Comparison of visual outcomes after bilateral implantation of extended range of vision and trifocal intraocular lenses.

PURPOSE: To compare visual outcomes after cataract surgery with bilateral implantation of 2 intraocular lenses (IOLs): extended range of vision and trifocal. METHODS: Each group of this prospective study comprised 40 eyes (20 patients). Phacoemulsification followed by bilateral implantation of a FineVision IOL (group 1) or a Symfony IOL (group 2) was performed. The following outcomes were assessed up to 1 year postoperatively: binocular uncorrected distance visual acuity (UDVA), binocular uncorrected intermediate visual acuity (UIVA) at 60 cm, binocular uncorrected near visual acuity (UNVA) at 40 cm, spherical equivalent (SE) refraction, defocus curves, mesopic and photopic contrast sensitivity, halometry, posterior capsule opacification (PCO), and responses to a patient questionnaire. RESULTS: The mean binocular values in group 1 and group 2, respectively, were SE -0.15 ± 0.25 D and -0.19 ± 0.18 D; UDVA 0.01 ± 0.03 logMAR and 0.01 ± 0.02 logMAR; UIVA 0.11 ± 0.08 logMAR and 0.09 ± 0.08 logMAR; UNVA 0.06 ± 0.07 logMAR and 0.17 ± 0.06 logMAR. Difference in UNVA between IOLs (p<0.05) was statistically significant. There were no significant differences in contrast sensitivity, halometry, or PCO between groups. Defocus curves were similar between groups from 0 D to -2 D, but showed significant differences from -2.50 D to -4.00 D (p<0.05). CONCLUSIONS: Both IOLs provided excellent distance and intermediate visual outcomes. The FineVision IOL showed better near visual acuity. Predictability of the refractive results and optical performance were excellent; all patients achieved spectacle independence. The 2 IOLs gave similar and good contrast sensitivity in photopic and mesopic conditions and low perception of halos by patients.

Diseño de un protocolo de enfermería para pacientes alérgicos al látex en nuestra unidad de hemodiálisis / No disponible

No disponible

Mastitis lúpica. Presentación de un caso / Lupus mastitis. A case report

Historia clínica: Mujer de 74 años con antecedentes deLupus Eritematoso Sistémico (LES) y de Lupus paniculitisque muestra lesiones clínica y radiológicamente sospechosasde malignidad en ambas mamas. Hallazgos patológicos:En la mama izquierda se diagnosticó un carcinomamucinoso y en ambas mamas cambios histológicos compatiblescon mastitis lúpica. Discusión: Se trata de una entidadrara. Se revisa la literatura (AU)

Case report: A 74 year old woman with systemic lupuserithematosus (SLE) and lupus panniculitis had clinicaland radiological findings suspicious of malignancy in bothbreasts. Pathology: A mucinous carcinoma was diagnosedin the left breast and histological changes suggestive oflupus mastitis were found in both breasts. Discussion: Thisunusual case is presented together with a review of the literature (AU)

[Neoplastic wounds. How nurses deal with them]. / Heridas neoplásicas. Abordaje desde enfermería.

The knowledge which nurses should have regarding the cicatrisation processes for neoplastic ulcers is important, as are the techniques and products designed for treatment of this type of lesions. On the other hand, we should be capable to provide positive reinforcement to increase the self-esteem of patients who undergo this type of wounds. This article was submitted at the VII National Symposium on Bed Sores and Chronic Wounds and at the First Latin American Congress on Ulcers and Wounds.

Heridas neoplásicas. Abordaje desde enfermería / Neoplastic Wounds, how nurses deal with them

Es importante el conocimiento que Enfermería debe tener sobre los procesos de cicatrización de las úlceras neoplásicas, así como de las técnicas y productos destinados para el cuidado de este tipo de lesiones. Por otro lado, debemos ser capaces de proporcionar refuerzos positivos para potenciar el autoconcepto y la autoestima de los pacientes que presentan este tipo de heridas. Este artículo fue expuesto en el VII Simposio Nacional de Úlceras por Presión y Heridas Crónicas y I Congreso Latinoamericano sobre Úlceras y Heridas(AU)

The knowledge which nurses should have regarding the cicatrisation processes for neoplastic ulcers is important, as are the techniques and products designed for treatment of this type of lesions. On the other hand, we should be capable to provide positive reinforcement to increase the self-esteem of patients who undergo this type of wounds. This article was submitted at the VII National Symposium on Bed Sores and Chronic Wounds and at the First Latin American Congress on Ulcers and Wounds(AU)

Diseño de estrategias de optimización del volumen de reinfusión en hemodiafiltración en línea / Design of strategies to optimize the reinfusion volume in online haemodiafiltration

El diseño de algoritmos clínicos para la optimización del volumen de reinfusión en Hemodiafiltración en línea en 16 pacientes con insuficiencia renal crónica ha permitido incrementar este parámetro relacionado con la eficacia de la técnica, creando un lenguaje intermedio entre los diferentes especialistas que intervienen en el problema. Una de las consecuencias más importantes ha sido la disminución de la variabilidad de la práctica clínica y de enfermería a la hora de establecer en estos pacientes el QI óptimo. A consecuencia de estas estrategias, los resultados preliminaries se ajustan al objetivo propuesto (AU)

The design of clinical algorithms to optimize the volume of reinfusion in online haemodiafiltration in 16patients with chronic renal insufficiency has made it possible to increase this parameter related to the efficacy of the technique, creating an intermediate language among the different specialists involved in the problem. One of the most important consequences has been to reduce the variability of clinical and nursing practice in establishing the optimum QI in such patients. As a result of these strategies, the preliminary results respond to the proposed aim (AU)