Tumor de células yuxtaglomerulares como causa de hipertensión curable: presentación de un caso / Juxtaglomerular cell tumour as a curable cause of hypertension: case presentation

La hipertensión arterial es una enfermedad de alta prevalencia y siempre deben tenerse en cuenta las causas secundarias que pueden originarla, debido a que el tratamiento y el pronóstico difieren entre estas y la hipertensión esencial. Presentamos el primer caso reportado en Argentina de una paciente de 21 años con hipertensión arterial e hipopotasemia, debido a un tumor de células yuxtaglomerulares productor de renina, el cual fue diagnosticado tras siete años de evolución (AU)

Arterial hypertension is a highly prevalent disease and its secondary causes must always be kept in mind because the treatment and prognosis differ between these and essential hypertension. Here we present the first reported case in Argentina of a 21-year-old patient with arterial hypertension and hypokalaemia due to a renin-secreting juxtaglomerular cell tumour, which was diagnosed after seven years of development (AU)

Juxtaglomerular cell tumour as a curable cause of hypertension: case presentation.

Arterial hypertension is a highly prevalent disease and its secondary causes must always be kept in mind because the treatment and prognosis differ between these and essential hypertension. Here we present the first reported case in Argentina of a 21-year-old patient with arterial hypertension and hypokalaemia due to a renin-secreting juxtaglomerular cell tumour, which was diagnosed after seven years of development.

Timoma esclerosante (antiguo): Un tumor poco frecuente de mediastino anterior. Presentación de un caso / Sclerosing thymoma: A rare anterior mediastinal tumour. A case report

El timoma esclerosante es un tumor muy poco frecuente de mediastino anterior que representa menos del 1% de los timomas. Se presenta el caso de un hombre de 46 años, asintomático, al cual se le diagnosticó un tumor mediastínico en una radiografía torácica de control. Se realizó una biopsia transtorácica que no fue concluyente. En la cirugía se observó un tumor sólido adherido a la pared anterior del tórax, pleura y pericardio. Microscópicamente la neoplasia presentaba un 90% de estroma fibrocolagenoso con aisladas células epiteliales sin atipia y abundantes linfocitos, diagnosticándose un timoma esclerosante. El paciente evolucionó favorablemente. Existen importantes diagnósticos diferenciales a considerar en lesiones mediastínicas esclerosantes, como una mediastinitis esclerosante, un tumor fibroso solitario yalgunos linfomas. Para un correcto diagnóstico histopatológico es necesario un amplio muestreo del tumor y realizar estudios de inmunohistoquímica (AU)

Sclerosing thymoma is a very rare anterior mediastinal tumour accounting for less than 1% of all thymomas. We report a case of an asymptomatic 46 year-old man with a mediastinal tumour discovered on a routine chest x-ray. A transthoracic tumour biopsy was inconclusive. Surgery revealed a tumour attached to the anterior thoracic wall, pleura and pericardium. Histologically, 90% of the neoplasm consisted of a fibrocollagen stroma with isolated epithelial cells which showed no atypia; lymphoid cells were not abundant. A diagnosis of sclerosing thymoma was made and the patient recovered well. The most important differential diagnoses to be considered in sclerosing lesions of the anterior mediastinum are sclerosing mediastinitis, solitary fibrous tumour and lymphomas. For a correct histopathological diagnosis, extensive tumour sampling is necessary and the immunohistochemistry must be studied (AU)

Tumor de células granulosas en vulva: reporte de un caso / Granular cell tumor of the vulva: case report

El tumor de células granulosas (TCG) es una entidad infrecuente de la piel y tejidos blandos. Ocurre con más frecuencia en mujeres de raza negra, entre la segunda y sexta década de vida. La localización habitual es la cavidad oral, pero pueden aparecer en otros sitios. El compromiso vulvar ha sido reportado en el 5-16%. Aunque la mayoría son benignos, existe una rara variante maligna agresiva. El tratamiento de elección es la escisión quirúrgica amplia. Presentamos un caso de TCG en la vulva de una mujer de 65 años de edad y revisamos la literatura.

Granulosa cell tumor (GCT) is an uncommon skin and soft tissues disease. It occurs most often in black women between secondand sixth decade of life. Usual location involves oral cavity, but may appear in other sites. Vulvar commitment has been reportedin 5-16% of the cases. Mostly benign, but there is a rare aggressive malignant variant. Treatment choice is wide surgical excision.We report a 65-year-old woman with GCT of the vulva and review the literature.

[Primary hydatid disease of the tibia. case report]. / Hidiatidosis osea primaria de tibia: presentación de un caso.

Hydatidosis is an endemic disease in different parts of the world. Its causal agent is the cestode from the genus Echinococcus. The most commonly affected organs in humans are liver and lung. Bone hydatid disease is a very rare entity, accounting for 0.5 to 4% of total cases. We report a case of a 58 year-old woman from La Rioja, Argentina, who consulted for left infapatellar pain and walking disability of eight months duration. Imaging studies showed a cystic lesion which involved metaphysis and diaphysis of left proximal tibia. Surgical resection was performed and histopathological study confirmed that it was a hydatid cyst. The patient did well and completed three cycles of treatment with albendazole. Currently, she has no evidence of disease and she recovered motility of her left leg. Primary hydatid bone disease, where there is no evidence of systemic disease, is even more unusual. Tibia involvement occurs in up to 15% of the cases. These lesions clinically manifest when they suffer any type of complications. Preoperative diagnosis is mainly made by imaging studies. Lesions are usually osteolytic and can involve cortical bone and extend to soft tissues. Differential diagnosis with inflammatory processes and bone tumors should is mandatory. Treatment is surgical and prognosis is poor due to its high morbi-mortality rate and recurrence risk from 70 to 80%.