Excellent response to mesotherapy as adjunctive treatment in male androgenetic alopecia.

Androgenetic alopecia (AGA) is the most common type of alopecia. Currently, only topical minoxidil and oral finasteride, for men, are approved for its treatment. We report a case of a patient with male pattern AGA treated with topical minoxidil and oral finasteride for 2 years, with partial improvement. At this point, we added mesotherapy to the previous treatment. The patient had 20 sessions of sterile mesotherapy blend, containing minoxidil, finasteride, biotin, and D-panthenol. We did the injections every two weeks and made the response assessment with global clinical photographs at the 10th and the 20th sessions when we noted a significant visible improvement in hair density and thickness. Mesotherapy or intradermotherapy is defined as a technique that involves the use of multiple intradermal injections of a mixture of compounds in low doses, at many points, near/over the affected sites. In our case, the patient had an excellent response to intradermotherapy as an adjunctive treatment, with no side effects. Although we still need additional clinical trials to standardize the therapy and treatment guidelines, mesotherapy seems to be a therapeutic option in the treatment of AGA, especially if the procedure happens in a medical facility, with correct indication and adequate execution of this promising technique.

Perfil clínico e epidemiológico de pacientes com fibrilação atrial / Clinical and epidemiological profile in atrial fibrillation

O objetivo deste estudo foi verificar o perfil clínico eepidemiológico em pacientes portadores de fibrilaçãoatrial (FA). Foi realizado estudo transversal com aplicaçãode questionário através de entrevistas aos pacientesno período de 01/08/2010 a 31/07/2011. A casuísticafoi composta de 99 pacientes, com idade médiade 64,8 ± 12,5 anos, predominância do sexo masculino(59,6%), maioria de etnia branca (90,9%) e encontravam-se em regime de internação hospitalar (85,8%).Doença de base mais prevalente foi a hipertensão arterialsistêmica (79,8%) e FA do tipo permanente foi amais encontrada. A estratégia de tratamento mais utilizadafoi o controle da frequência cardíaca e, emboraalguns pacientes tivessem indicação do uso de anticoagulante,esse tratamento não era utilizado por todos.

The aim of this study was to evaluate the clinical andepidemiological profile in patients with atrial fibrillation(AF). Sectional study was performed with a questionnairethrough interviews with patients in the periodfrom 01/08/2010 to 31/07/2011. The sample consistedof 99 patients, mean age 64.8 ± 12.5 years, malepredominance (59.6%), most were white (90.9%) andwere in inpatients hospital (85.8%). Underlying diseasewas more prevalent hypertension (79.8%) and permanenttype of AF was the most common. The most widelyused treatment strategy was the heart rate control and,although some patients had indication of the use of anticoagulants,such treatment was not used by everyone.