Tractable Bayes of skew-elliptical link models for correlated binary data.

Correlated binary response data with covariates are ubiquitous in longitudinal or spatial studies. Among the existing statistical models, the most well-known one for this type of data is the multivariate probit model, which uses a Gaussian link to model dependence at the latent level. However, a symmetric link may not be appropriate if the data are highly imbalanced. Here, we propose a multivariate skew-elliptical link model for correlated binary responses, which includes the multivariate probit model as a special case. Furthermore, we perform Bayesian inference for this new model and prove that the regression coefficients have a closed-form unified skew-elliptical posterior with an elliptical prior. The new methodology is illustrated by an application to COVID-19 data from three different counties of the state of California, USA. By jointly modeling extreme spikes in weekly new cases, our results show that the spatial dependence cannot be neglected. Furthermore, the results also show that the skewed latent structure of our proposed model improves the flexibility of the multivariate probit model and provides a better fit to our highly imbalanced dataset.

Flexible cloglog links for binomial regression models as an alternative for imbalanced medical data.

The complementary log-log link was originally introduced in 1922 to R. A. Fisher, long before the logit and probit links. While the last two links are symmetric, the complementary log-log link is an asymmetrical link without a parameter associated with it. Several asymmetrical links with an extra parameter were proposed in the literature over last few years to deal with imbalanced data in binomial regression (when one of the classes is much smaller than the other); however, these do not necessarily have the cloglog link as a special case, with the exception of the link based on the generalized extreme value distribution. In this paper, we introduce flexible cloglog links for modeling binomial regression models that include an extra parameter associated with the link that explains some unbalancing for binomial outcomes. For all cases, the cloglog is a special case or the reciprocal version loglog link is obtained. A Bayesian Markov chain Monte Carlo inference approach is developed. Simulations study to evaluate the performance of the proposed algorithm is conducted and prior sensitivity analysis for the extra parameter shows that a uniform prior is the most convenient for all models. Additionally, two applications in medical data (age at menarche and pulmonary infection) illustrate the advantages of the proposed models.

On a new type of Birnbaum-Saunders models and its inference and application to fatigue data.

The Birnbaum-Saunders distribution is a widely studied model with diverse applications. Its origins are in the modeling of lifetimes associated with material fatigue. By using a motivating example, we show that, even when lifetime data related to fatigue are modeled, the Birnbaum-Saunders distribution can be unsuitable to fit these data in the distribution tails. Based on the nice properties of the Birnbaum-Saunders model, in this work, we use a modified skew-normal distribution to construct such a model. This allows us to obtain flexibility in skewness and kurtosis, which is controlled by a shape parameter. We provide a mathematical characterization of this new type of Birnbaum-Saunders distribution and then its statistical characterization is derived by using the maximum-likelihood method, including the associated information matrices. In order to improve the inferential performance, we correct the bias of the corresponding estimators, which is supported by a simulation study. To conclude our investigation, we retake the motivating example based on fatigue life data to show the good agreement between the new type of Birnbaum-Saunders distribution proposed in this work and the data, reporting its potential applications.