Migration of formaldehyde and melamine from melaware and other amino resin tableware in real life service.

The migration of formaldehyde and melamine monomers has been measured on 90 samples of plastic tableware in three different situations - new articles, already used articles and artificially aged articles - by using simulant, contact times and temperatures prescribed by Commission Regulation (EU) No. 10/2011. Formaldehyde was determined by ultraviolet spectroscopy analysis of the coloured complex obtained by reaction with chromotropic acid. Melamine was measured by an ultra high performance liquid chromatography method. Fourier Transformed - Infrared Analysis was applied to characterise the plastic. The results highlighted the presence of different amino resins based on formaldehyde-melamine, urea-formaldehyde or melamine-urea-formaldehyde with different migration behaviour. The migration of monomers was related to progressive degradation of the resins. Ageing studies demonstrated that the potential degradation of the resins and the consequent migration of the monomers may continue throughout the service life of the product. The specific migration limit (SML) of melamine was exceeded after ageing.

Short-Term Repeatability of Magnetic Resonance Elastography at 3.0T: Effects of Motion-Encoding Gradient Direction, Slice Position, and Meal Ingestion.

PURPOSE: Magnetic resonance elastography (MRE) can estimate liver stiffness (LS) noninvasively. We prospectively assessed whether motion-encoding gradient (MEG) direction, slice position, or high-caloric food intake affects the repeatability of MRE measurements of LS. MATERIALS AND METHODS: Twenty healthy volunteers (8 women, 12 men; age, 48 ± 12 years) were imaged in a 3.0T scanner at four timepoints: twice after overnight fasting (B1 , B2 ) and twice after consuming a 1050-calorie standardized meal (A1 , A2 ; after 30 and 60 min, respectively). Each session comprised sequential MRE acquisitions in which MEG was applied in three orthogonal directions with three slices positioned over the liver for each. Between sessions, the participants were repositioned to assess test-retest reproducibility. RESULTS: The LS measurements before/after food intake were 3.36 ± 1.31 kPa/3.22 ± 1.03 kPa, 2.04 ± 0.33 kPa/2.27 ± 0.38 kPa, and 2.47 ± 0.50 kPa/2.64 ± 0.76 kPa for MEG superimposed along the anterior-posterior (AP), foot-head (FH), and right-left (RL) directions, respectively. Before and after food intake, LS estimates were lower and more reproducible (<10% coefficient of variation) when the MEG was in the FH direction, not the AP or RL direction. Liver stiffness estimates were significantly elevated after meal consumption when the MEG was in the FH direction (P < 0.05 for B1 vs. A1 , B1 vs. A2 , B2 vs. A1 , and B2 vs. A2 ). CONCLUSION: MRE estimates of LS were highly reproducible, particularly when MEG was applied in the FH direction, suggesting that this method could be used for long-term monitoring of antifibrotic therapy without repeated biopsies. High-caloric food intake resulted in slightly elevated LS on MRE.

A simulation/optimization model for selecting infrastructure alternatives in complex water resource systems.

The paper introduces a simulation/optimization procedure for the assessment and the selection of infrastructure alternatives in a complex water resources system, i.e. in a multisource (reservoirs) multipurpose bulk water supply scheme. An infrastucture alternative is here a vector X of n decision variables describing the candidate expansions/new plants/water transfers etc. Each parameter may take on a discrete number of values, with its own investment cost attached. The procedure uses genetic algorithms for the search of the optimal vector X through operators mimicking the mechanisms of natural selection. For each X, the value of the objective function (O.F.) is assessed via a simulation model. Simulation is necessary as the O.F. contains, besides investment costs, also incremental operation costs and benefits that depend on the incremental water amounts which the alternative can provide. The simulation model transforms a thirty-year hydrologic input at daily/monthly scale in water allocations, accounting for the usual nonnegativity constraints and using some simple, sytem-specific rules aimed at reducing spills and at sharing water deficits among demand centres. Different O.Fs and constraints have been tested, such as incremental financial cost/benefit minimization under various maximum water deficit constraints scenarios or cost/benefit mimization including scarcity costs. This latter approach has the advantage of implicitly allowing for the magnitude of deficits, but requires the assessment of deficit-scarcity cost relationships. The application of the procedure to a water resources system in south-western Sicily shows that the model is able to converge to results that are consistent with the planning options expressed by the selected O.Fs.