RESUMO
The Pick's disease categorization as a entity founded in its clinical presentation is a polemical matter of discussion between continental european and anglosaxon groups. We present a clinical case which support a characteristic pathochrony, anatomical localization and initial symptomatology of Pick's disease, which possibility its clinical differentiation with other dementias.
Assuntos
Transtornos Cognitivos/complicações , Transtornos Cognitivos/diagnóstico , Demência/complicações , Feminino , Humanos , Pessoa de Meia-Idade , Testes NeuropsicológicosRESUMO
The aim of this paper is to review the question of depression in patients with multiple sclerosis (MS). Morbidity and methodological difficulties in the investigation of depressive states in MS are analyzed. Prevalence of depression in MS in previous series is critically compared. The role of chronic invalidity and topography of demyelinating lesions in the development of depression are considered. We also review the treatment of depressive states and future guidelines for investigation of this topic.
Assuntos
Depressão/etiologia , Esclerose Múltipla/psicologia , Encéfalo/fisiopatologia , Doenças Desmielinizantes/psicologia , Depressão/epidemiologia , Depressão/terapia , Transtorno Depressivo/epidemiologia , Transtorno Depressivo/etiologia , Transtorno Depressivo/fisiopatologia , Transtorno Depressivo/terapia , Humanos , Transtornos do Humor/epidemiologia , Transtornos do Humor/etiologia , Transtornos do Humor/fisiopatologia , Esclerose Múltipla/fisiopatologia , Prevalência , Estudos Retrospectivos , Medula Espinal/fisiopatologiaRESUMO
A consecutive sample of 50 patients with a diagnosis of definite multiple sclerosis was evaluated by means of the Clinical Interview Schedule (CIS) and other psychopathological instruments. A global prevalence of psychopathology of 54% was found, with the prevalence of depression being 22%. Moreover, 46% of the sample presented signs indicative of neuropsychological deterioration in the Benton Visual Retention Test. The association between the presence of psychopathology and the social and neurological characteristics of the sample was also investigated, with results of low significance.
Assuntos
Transtornos Mentais/diagnóstico , Esclerose Múltipla/psicologia , Adolescente , Adulto , Transtorno Depressivo/diagnóstico , Transtorno Depressivo/epidemiologia , Feminino , Humanos , Masculino , Transtornos Mentais/epidemiologia , Pessoa de Meia-Idade , Esclerose Múltipla/complicações , Transtornos Neurocognitivos/diagnóstico , Transtornos Neurocognitivos/epidemiologia , Testes Neuropsicológicos , Prevalência , Escalas de Graduação PsiquiátricaRESUMO
The objective of this paper is to present the results of the translation and adaptation into Spanish of a questionnaire (The Sickness Impact Profile --SIP--) for measuring the physical and psychosocial dysfunctions generated by a disease. For this the SIP, together with some clinical measures of physical and psychosocial status were administered to a series of 50 patients afflicted by multiple sclerosis. We found not only that the SIP could be considered a good instrument for measuring the physical and psychosocial impact of illness, but also that it is adequate to differentiate in it a physical and a psychosocial dimensions.
