Association of indoor air quality and preschool children's respiratory symptoms.

BACKGROUND: This study aimed to assess the association between exposure to indoor air pollution in DCCs (Child Day Care Centers) and the respiratory symptoms of children under 6 years old. METHODS: Air quality data were collected three times regarding to seasonal variation. Pollutants measured in 11 DCCs included PM10, CO, NO2, SO2, O3, benzene, bacteria, fungi, and dust mite. The frequencyof respiratory symptoms including coughing, rhinitis, and dyspnea were recorded via teacher and parent-report questionnaires. Fractional exhaled nitric oxide (FENO) levels were measured to assess airway inflammation. RESULTS: 436 children participated in the study. 83% completed data collection in all 3 seasons. The frequency of rhinitis correlated with PM10 (IRR=70.3, 95%CI=12.4-399.7, p<0.001), CO (IRR=3.2, 95%CI=2.4-4.2, p<0.001), benzene (IRR=2.3, 95%CI=1.8-3.2, p<0.001) and D.Pteronyssinus level (IRR=2.1, 95%CI=1.7-2.7, p<0.001). The frequency of coughingcorrelated with levels of PM10 (IRR=15.2, 95%CI=3.0-78.2, p<0.001), CO (IRR=2.8, 95%CI=2.1-3.7, p<0.001), benzene (IRR=1.4, 95%CI=1.1-1.9, p=0.02). The frequency of dyspnea correlated with D.Pteronyssinus level (IRR=3.9, 95%CI=1.7-9.1, p=0.001). FENO levels associated with high benzene levels (OR=5.9, 95%CI=1.5-22.9, p=0.01). The majority of DCCs had at least one PM10 measurement above the standard level, and these high levels were noted in all 3 seasons. Three DCCs had PM10 levels above the standard level in all seasons. 64% of the DCCs had indoor bacterial counts above the standard level in all seasons. CONCLUSIONS: PM10 and bacterial count is a significant problem in Bangkok metropolitan DCCs. The respiratory symptoms of children positively associated with PM10, CO, benzene and dust mite levels.

Pattern of Uveitis in a Tertiary Ophthalmology Center in Thailand.

PURPOSE: To study the etiology and pattern of uveitis in a tertiary ophthalmology center in Thailand. METHODS: A cross-sectional study was conducted on uveitis patients presenting to a uveitis clinic at Ramathibodi Hospital, Thailand, between February 2014 and January 2015. RESULTS: A total of 758 uveitis patients were enrolled into this study. The most common identified cause was herpetic uveitis (17.2%), followed by Vogt-Koyanagi-Harada disease (13.5%), cytomegalovirus uveitis (12.7%), and HLA-B27/spondyloarthropathy-associated uveitis (12.4%). CONCLUSIONS: Herpetic uveitis was the commonest form of infectious uveitis, whereas Vogt-Koyanagi-Harada disease was most frequently seen as the non-infectious cause of uveitis in Thailand.