[Content of carcinogenic nitroso compounds in food products]. / Soderzhanie kantserogennykh nitrozosoedinenii v pishchevykh produktakh.

The data are provided on the content of carcinogenous N-nitroso compounds in foods manufactured in a region with a high gastric carcinoma incidence. It was found that foods under analysis have a high content of carcinogenous nitroso compounds. The foods were also found to contain N-nitrosopiperidine, a carcinogen inducing tumors of the gastrointestinal tract.

[Carcinogenic nitrosamine content of food products of the Moldavian SSR]. / Soderzhanie kantserogennykh nitrozaminov v pishchevykh produktakh Moldavskoi SSR.

The authors provide data concerning the content of carcinogenous N-nitrosocompounds in foods manufactured in the Moldavian SSR. Over 100 samples of foods of both vegetable and animal origin have been analyzed. It has been found that foods manufactured in the Moldavian SSR are contaminated with carcinogenous N-nitrosamines but to an insignificant degree. It is concluded that the degree of a relative risk may be regarded as negligible.

[N-nitroso compounds in the food products in regions with a high stomach cancer morbidity]. / N-nitrozosoedineniia v pishchevykh produktakh raionov s povyshennoi zabolevaemost'iu rakom zheludka.

The content of cancerogenous N-nitrosamines (NA) was examined in food marketed in the regions with the increased gastric carcinoma incidence. The food was analyzed by means of the fluorescent technique. Some of food products, such as lard, corned beef, dried mushrooms were found to be contaminated with volatile NA, while vegetable and milk products contained negligible amounts of NA or did not contain them at all.

[Role of food and other modifying factors in the development of stomach cancer]. / Rol' pishchevykh i drugikh modifitsiruiushchikh faktorov v razvitii raka zheludka.

The effect of the alimentary, nervous, hormonal and drug factors on gastric secretion and resistance to the action of chemical cancerogenic substances was studied in four experiments. It was established that all these factors affecting gastric secretion for a long time, exert through it an effect on gastric resistance to the action of chemical cancerogenic substances. It was shown as well that gastric resistance to cancerogenic effects correlated directly with the rate of gastric secretion. The higher it was the stronger resistance the stomach exhibited to the action of chemical cancerogenic substances. Decreased gastric secretion is a factor predisposing to cancer of the stomach rather than an obligatory precancerous condition.

[The secretory function of the stomach in pre-tumorous conditions and tumors]. / Sekretornaia funktsiia zheludka pri predopukholevykh sostoianiiakh i opukholiakh

The effect of 3-methylcholanthrene, pretumor and tumor changes in the stomach on its secretory function was studied on 38 rats. Gastric secretion was not found to change due to the presence of the carcinogen in the stomach or due to developing pre-tumor changes in it. However, the developing tumor would produce considerable shifts in gastric secretion towards achylia. Such a reduction in the secretion results from a diminished functional area of the stomach and, presumably, from toxemia phenomena.